Method and system for patient-specific modeling of blood flow
First Claim
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1. A system for planning treatment for a patient, the system comprising:
- at least one computer system configured to;
receive patient-specific data regarding a geometry of an anatomical structure of the patient;
create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data;
determine a first blood flow characteristic within the anatomical structure of the patient based on the three-dimensional model and a physics-based model relating to the anatomical structure of the patient, the physics-based model having fewer than three dimensions;
modify the three-dimensional model; and
determine a second blood flow characteristic within the anatomical structure of the patient based on the modified three-dimensional model,wherein each of the first and second blood flow characteristics is chosen from blood pressure, blood velocity, blood flow rate, and fractional flow reserve within at least the portion of the anatomic structure.
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Abstract
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient'"'"'s heart, and create a three-dimensional model representing at least a portion of the patient'"'"'s heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient'"'"'s heart and determine a fractional flow reserve within the patient'"'"'s heart based on the three-dimensional model and the physics-based model.
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Citations
30 Claims
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1. A system for planning treatment for a patient, the system comprising:
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at least one computer system configured to; receive patient-specific data regarding a geometry of an anatomical structure of the patient; create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data; determine a first blood flow characteristic within the anatomical structure of the patient based on the three-dimensional model and a physics-based model relating to the anatomical structure of the patient, the physics-based model having fewer than three dimensions; modify the three-dimensional model; and determine a second blood flow characteristic within the anatomical structure of the patient based on the modified three-dimensional model, wherein each of the first and second blood flow characteristics is chosen from blood pressure, blood velocity, blood flow rate, and fractional flow reserve within at least the portion of the anatomic structure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method for planning treatment for a patient using a computer system, the method comprising:
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receiving, at least one computer system, patient-specific data regarding a geometry of an anatomical structure of the patient; creating, using the at least one computer system, a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data; determining, using the at least one computer system, a first blood flow characteristic within the anatomical structure of the patient based on the three-dimensional model and a physics-based model relating to the anatomical structure of the patient, the physics-based model having fewer than three dimensions; modifying, using the at least one computer system, the three-dimensional model; and determining, using the at least one computer system, a second blood flow characteristic within the anatomical structure of the patient based on the modified three-dimensional model, wherein each of the first and second blood flow characteristics is chosen from blood pressure, blood velocity, blood flow rate, and fractional flow reserve within at least the portion of the anatomical structure. - View Dependent Claims (11, 12, 13)
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14. A system for planning treatment for a patient, the system comprising:
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at least one computer system configured to; receive patient-specific imaging data regarding a geometry of at least a portion of an anatomical structure of the patient; create a three-dimensional model representing the portion of the anatomical structure based on the patient-specific imaging data, the three-dimensional model representing at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta; determine a first blood flow characteristic within at least the portion of the plurality of coronary arteries based on the three-dimensional model and at least one physics-based model, the at least one physics-based model having fewer than three dimensions; receive input from a user regarding a plan of treatment; modify the three-dimensional model based on the received input; and determine a second blood flow characteristic at a plurality of locations within at least the portion of the plurality of coronary arteries based on the modified three-dimensional model; wherein each of the first and second blood flow characteristics is chosen from blood pressure, blood velocity, blood flow rate, and fractional flow reserve within at least the portion of the plurality of coronary arteries. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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21. A method for planning treatment for a patient, the method comprising:
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receiving, at least one computer system, patient-specific imaging data regarding a geometry of at least a portion of an anatomical structure of the patient; creating, using the at least one computer system, a three-dimensional model representing the portion of the anatomical structure based on the patient-specific imaging data, the three-dimensional model representing at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta; determining, using the at least one computer system, a first blood flow characteristic within at least the portion of the plurality of coronary arteries based on the three-dimensional model and at least one physics-based model, the at least one physics-based model having fewer than three dimensions; inputting into the at least one computer system information regarding a plan of treatment, the plan of treatment indicating a change in geometry within the portion of the plurality of coronary arteries; modifying the three-dimensional model based on the information regarding the plan of treatment; and determining, using the at least one computer system, a second blood flow characteristic at a plurality of locations within at least the portion of the plurality of coronary arteries based on the modification; wherein each of the first and second blood flow characteristics is chosen from blood pressure, blood velocity, blood flow rate, and fractional flow reserve within at least the portion of the plurality of coronary arteries. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification