Laboratory instrumentation information management and control network

• US 8,812,329 B2
• Filed: 04/04/2007
• Issued: 08/19/2014
• Est. Priority Date: 07/17/2003
• Status: Active Grant

• Current Assignee: Ventana Medical Systems Incorporated (Roche Holding AG)
• Original Assignee: Ventana Medical Systems Incorporated (Roche Holding AG)
• Inventors: Showalter, Wayne, Larson, Alain L.
• Primary Examiner(s): Lubin, Valerie
• Assistant Examiner(s): Reyes, Reginald R
• Application Number:
  US11/732,628
• Publication Number:
  US 20070196909A1
• Time in Patent Office: 2,694 Days
• Field of Search: 705/2
• US Class Current: 705/2
• CPC Class Codes: G01N 2035/00881 network configurations
• CPC Class Codes: G01N 35/00732 Identification of carriers, materials or components in automatic analysers
• CPC Class Codes: G06Q 10/00 Administration; Management
• CPC Class Codes: G06Q 10/06 Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
• CPC Class Codes: G06Q 10/10 Office automation; Time management
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis

Abstract

An interface point network (IPN) and a method for communication with a laboratory information system using an IPN, wherein the IPN includes at least one host computer in communication with at least one laboratory instrument, the laboratory information system and an interface point server in communication with the host computer and the laboratory information system, the interface point server being configured to function as a communication interface between the host computer and the laboratory information system in a manner responsive to a predetermined communication protocol. Use of bar code and RFID labels for tracking samples and in maintaining sample data is described.

Claims

1. A method for processing a sample in an anatomical pathology laboratory comprising:

providing a host controlling at least one instrument in the anatomical pathology laboratory, said host being configured to have at least one local data element and at least one global data element and said host being configured to identify samples in the laboratory using radio frequency identification labels associated with the samples, said at least one global data element having a common data definition and data value used by said host and at least one other host connected to said host, said at least one local data element having a data definition and data value used only by said host, wherein said at least one instrument controlled by the host includes a first stainer that uses a first reagent, wherein said at least one global data element includes a first global data element that is associated with the first reagent and indicates the first reagent is currently owned by the host thereby indicating that the first reagent physically resides at an instrument controlled by the host;

receiving a first of said samples, said first sample being a tissue sample associated with a radio frequency identification label encoded with a tissue sample identifier including a first part representing a tissue source, a second part representing a year associated with the tissue sample, and a tissue sequence number;

partitioning the first sample into one or more blocks, each of said blocks associated with a different block identifier;

preparing a set of one or more slides from said first sample, each of said one or more slides having a portion of said first sample on a surface of said each slide and being cut from one of said blocks;

preparing a radio frequency identification label for each of said one or more slides in the set, said radio frequency identification label being affixed to said each slide and having a slide identifier encoded thereon that uniquely identifies said each slide, wherein said slide identifier for said each slide having the portion of the first sample thereon includes the tissue sample identifier, a block identifier associated with one of the blocks from which the portion was cut, and a slide sequence number;

performing one or more processing steps in said laboratory to at least a first slide of said set of one or more slides, wherein said performing includes;

reading the slide identifier from the radio frequency identification label for said first slide;

accessing information for said first slide in a database using said slide identifier of the first slide, wherein said accessing is performed by a computer using said slide identifier and obtains information including a first staining protocol which indicates to perform staining of the first slide using one or more reagents including said first reagent;

staining said first slide in accordance with the first staining protocol using said first stainer controlled by the first host; and

writing to said radio frequency identification label of said first slide by encoding said radio frequency identification label with information related to at least one of said one or more processing steps as said first slide is processed.

2. The method of claim 1, wherein said information written to said radio frequency identification label of said first slide includes at least one of patient information, hospital accession information, test information, and batch information used to identify at least one other slide and said each slide as being from a same processing batch.

3. The method of claim 1, wherein said information includes test information about at least one test performed on said first slide in one of the processing steps in the anatomical pathology laboratory.

4. The method of claim 3, further comprising:

reading said test information from said radio frequency identification label of said first slide in connection with a test to be performed to said first slide as a step in laboratory processing, said reading being performed prior to performing said test in order to verify processing for said test.

5. The method of claim 4, further comprising:

writing to said radio frequency identification label of said first slide by encoding said radio frequency identification label of the first slide with additional information about said test, said additional information including at least one of;

time, date, test parameters, filename, test results, information about a reagent used in testing, information about a technician performing a processing step, and information about an instrument used to process said first slide.

6. The method of claim 5, wherein said filename identifies an image file.

7. The method of claim 5, further comprising:

reading at least a portion of said additional information;

determining a diagnosis in accordance with said portion; and

encoding said radio frequency identification label of said first slide with data about said diagnosis.

8. The method of claim 2, wherein said information written to said radio frequency identification label of the first slide includes batch information, and the method further comprising:

determining a plurality of slides belonging to a same group in accordance with said batch information encoded on radio frequency identification labels of said plurality of slides.

9. The method of claim 1, further comprising:

writing information to said radio frequency identification label of said first slide in the anatomical pathology laboratory at a processing point when said staining is performed to said first slide.

10. The method of claim 1, further comprising:

receiving, by said radio frequency identification label associated with the first slide, an interrogator signal;

transmitting, by said radio frequency identification label associated with the first slide in response to said interrogator signal, an electromagnetic response signal including at least a first slide identifier used by said host for uniquely identifying said first slide.

11. The method of claim 10, wherein said electromagnetic response signal is produced using information encoded in said first radio frequency identification label associated with said first slide.

12. The method of claim 11, further comprising:

determining a location of said first slide in said anatomical pathology laboratory in accordance with said electromagnetic response signal.

13. The method of claim 1, further comprising:

receiving, by said radio frequency identification label associated with said first sample, an interrogator signal;

transmitting, by said radio frequency identification label associated with said first sample in response to said interrogator signal, an electromagnetic response signal including at least a first portion used by said host for uniquely identifying said first sample.

14. The method of claim 1, further comprising:

comparing, as part of a quality control check at a processing point in the anatomical pathology laboratory, a portion of information read from the radio frequency identification label associated with the first sample to other information stored in a database used by said host.

15. The method of claim 1, wherein said slide identifier associated with said each slide is used to access from the database one or more data elements associated with said each slide, said one or more data elements including a global data element.

16. The method of claim 15, wherein said global data element is any of a case identifier, a staining protocol used to process said each slide, a reagent used to process said each slide, and a location of an image file containing image results for said each slide.

17. The method of claim 1, wherein said first part of the tissue sample identifier includes a first letter of an alphabet if said tissue source is surgery, a second letter of an alphabet if said tissue source is bone marrow, and another letter of an alphabet if otherwise.

18. The method of claim 1, wherein said host and said at least one other host are in communication with an interface point server that facilitates synchronization and replication of said at least one global data element between said host and said at least one other host.