System and method for tissue ablation in a body cavity

• US 8,814,796 B2
• Filed: 01/10/2012
• Issued: 08/26/2014
• Est. Priority Date: 01/10/2012
• Status: Active Grant

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Martin, Gregory T., Churchill, William L., Beaudet, Daniel, Rioux, Robert F.
• Primary Examiner(s): Cattungal, Sanjay
• Application Number:
  US13/347,501
• Publication Number:
  US 20130178738A1
• Time in Patent Office: 959 Days
• Field of Search: 600429-469, 606 22- 50, 607101-120
• US Class Current: 600/437
• CPC Class Codes: A61B 18/1485 having a short rigid shaft for accessing the inner body through natural openings
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/320069 for ablating tissue
• CPC Class Codes: A61B 2017/32007 with suction or vacuum means
• CPC Class Codes: A61B 2017/320071 with articulating means for working tip
• CPC Class Codes: A61B 2018/00559 Female reproductive organs
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00779 Power or energy
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00875 Resistance or impedance
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61B 8/0858 involving measuring tissue layers, e.g. skin, interfaces
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00

Abstract

A tissue ablation system and method of forming same includes an ablation device having a substrate with an outer surface and energy transport elements coupled to the outer surface. The substrate is configured to have a shape that approximates an interior shape of a uterus. The system and method further including an energy source electrically coupled to the energy transport elements and at least one ultrasonic transducer positioned in a lateral region of the uterus.

Claims

1. A tissue ablation system comprising:

an ablation device including an elongate support member, the elongate support member having a proximal end and a distal end and defining a lumen therethrough in communication with an opening in the distal end, a substrate carried by the distal end, the substrate having an outer surface and configured to have a shape that approximates an interior shape of a uterus; and

energy transport elements coupled to the outer surface of the substrate;

an energy source electrically coupled to the energy transport elements; and

at least one ultrasonic transducer coupled to the outer surface of the substrate so that when the substrate is positioned within the uterus, the at least one ultrasonic transducer is positioned in a lateral region of the uterus.

2. The tissue ablation system of claim 1, wherein at least two ultrasonic transducers are positioned on the outer surface of the substrate so that when the substrate is positioned within the uterus, the least two ultrasonic transducers are positioned in opposing lateral regions of the substrate.

3. The tissue ablation system of claim 1, further comprising at least one ultrasonic transducer positioned on the outer surface of the substrate so that when the substrate is positioned within the uterus, the at least one ultrasonic transducer is positioned in a medial region of the substrate.

4. The tissue ablation system of claim 1, wherein the substrate is an electrode carrier and the energy transport elements are electrodes.

5. The tissue ablation system of claim 1, wherein the energy source is a radiofrequency source.

6. The tissue ablation system of claim 1, further comprising a measurement system configured to generate a non-image based visual indication so that a user can track the progress of tissue removal during an ablation process.

7. The tissue ablation system of claim 6, wherein the measurement system is configured to modulate the energy source during the ablation process.

8. The tissue ablation system of claim 1, further comprising one or more sensors positioned near the lateral region of the substrate, the one or more sensors configured to sense a force applied to the outer surface of the substrate.

9. The tissue ablation system of claim 1, further comprising a spring coupled to the outer surface of the substrate, wherein the at least one ultrasonic transducer is coupled to the spring.

10. The tissue ablation system of claim 1, further comprising a processor coupled to the at least one ultrasonic transducer and coupled to the energy source, the processor configured to receive information from the at least one ultrasonic transducer in order to determine a parameter and configured to terminate power to the energy source based on the parameter, wherein the parameter includes ablation depth.

11. The tissue ablation system of claim 1, wherein the at least one ultrasonic transducer is fixedly coupled to the substrate.

12. The tissue ablation system of claim 1, further comprising a processor coupled to the at least one ultrasonic transducer, the processor configured to calculate a tissue thickness based on density information from the at least one ultrasonic transducer.

13. The tissue ablation system of claim 12, wherein the processor configured to calculate tissue thickness for a plurality of tissue layers.

14. The tissue ablation system of claim 1, wherein the shape includes right and left lateral regions that extend toward each fallopian tube.

15. A method of ablating tissue in a uterus, comprising:

accessing the uterus transcervically with an elongate tubular device;

distending the uterus with the elongate tubular device by expanding a working end of the elongate tubular device, wherein the working end includes a substrate and an ultrasonic transducer coupled to an outer surface of the substrate, and wherein expanding a working end of the elongate tubular device includes positioning the ultrasonic transducer in a lateral region of the uterus;

receiving an indication the ultrasonic transducer is in contact with the tissue to be ablated;

applying a vacuum to remove fluid through the tubular device;

receiving a non-image based visual indication of a thickness of the tissue to be ablated;

activating the elongate tubular device to ablating tissue in the uterus;

maintaining contact between the ultrasonic transducer and the tissue to be ablated during at least a portion of the ablating step; and

deactivating the elongate tubular device upon achieving a desired ablation depth.

16. The method of claim 15, further comprising

generating a non-image based indication of a thickness of the tissue to be ablated using the at least one ultrasonic transducer.

17. The method of claim 15, further comprising

modulating the ablation based on ablation depth.