Delivery of biological compounds to ischemic and/or infarcted tissue
First Claim
1. A method of identifying a tissue region of interest for treatment, comprising:
- expanding a non-inflatable barrier or membrane defining an open area which is in fluid communication with an environment external to the barrier or membrane and projecting distally from a deployment catheter against the tissue region of interest;
urging a transparent fluid into the open area such that an opaque fluid is displaced therefrom;
visualizing the tissue region of interest through the transparent fluid;
assessing at least one parameter of the tissue region; and
treating the tissue region based upon an assessment of the at least one parameter.
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Accused Products
Abstract
The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.
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Citations
18 Claims
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1. A method of identifying a tissue region of interest for treatment, comprising:
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expanding a non-inflatable barrier or membrane defining an open area which is in fluid communication with an environment external to the barrier or membrane and projecting distally from a deployment catheter against the tissue region of interest; urging a transparent fluid into the open area such that an opaque fluid is displaced therefrom; visualizing the tissue region of interest through the transparent fluid; assessing at least one parameter of the tissue region; and treating the tissue region based upon an assessment of the at least one parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification