Integrated device for surface-contact sampling, extraction and electrochemical measurements
First Claim
1. A device for determining the presence of an analyte in a fluid sample comprising:
- a. a collection chamber containing an absorbent hydrogel material configured to absorb an analyte;
b. a fluidic channel connected to the collection chamber;
c. a sensing chamber connected to the fluidic channel;
d. a compressible housing configured to facilitate transfer of an extraction fluid contained in the sensing chamber to the collection chamber upon compression of said housing, the extraction fluid capable of dissolving the absorbed analyte, the compressible housing further configured to provide transfer of the analyte laden extraction fluid back to the sensing chamber upon release of said housing,wherein a material that specifically detects the analyte is contained in the fluidic channel or the sensing chamber, andwherein the sensing chamber is operably linked to a processor containing a potentiostat that allows detection of the analyte using electrochemical sensing.
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Abstract
The invention relates to a device and method for non-invasive detection of an analyte in a fluid sample. In one embodiment, the device comprises: a collection chamber containing an absorbent hydrogel material; a fluidic channel connected to the collection chamber; a sensing chamber connected to the fluidic channel, wherein the device is comprised of a compressible housing that allows transfer of fluid collected by the collection chamber to be transferred to be extracted and withdrawn to the sensing chamber upon compression of the device, wherein the sensing chamber contains a material that specifically detects the analyte and wherein the sensing chamber is operably linked to a processor containing a potentiostat that allows detection of the analyte using electrochemical sensing.
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Citations
18 Claims
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1. A device for determining the presence of an analyte in a fluid sample comprising:
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a. a collection chamber containing an absorbent hydrogel material configured to absorb an analyte; b. a fluidic channel connected to the collection chamber; c. a sensing chamber connected to the fluidic channel; d. a compressible housing configured to facilitate transfer of an extraction fluid contained in the sensing chamber to the collection chamber upon compression of said housing, the extraction fluid capable of dissolving the absorbed analyte, the compressible housing further configured to provide transfer of the analyte laden extraction fluid back to the sensing chamber upon release of said housing, wherein a material that specifically detects the analyte is contained in the fluidic channel or the sensing chamber, and wherein the sensing chamber is operably linked to a processor containing a potentiostat that allows detection of the analyte using electrochemical sensing. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification