Coatings for medical devices comprising a therapeutic agent and a metallic material
First Claim
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1. An implantable intravascular stent comprising:
- (a) a stent sidewall structure defining a surface; and
(b) a coating comprising(i) a first coating composition formed of a material selected from the group consisting of one or more therapeutic agents and one or more polymers, the first coating composition contacting at least a portion of the surface of the stent sidewall structure wherein the first coating composition has a first thickness measured from the surface of the stent sidewall structure; and
(ii) a second coating composition comprising a material different from the first coating composition, the second coating composition comprising a metallic material and being substantially free of any polymer, the second coating contacting at least a portion of the surface of the stent sidewall structure, at least a portion of the second coating composition being disposed adjacent to the first coating composition on the surface of the stent sidewall structure, wherein the second coating composition has a second thickness measured from the surface of the stent sidewall structure; and
wherein the second thickness of the second coating composition is the same as or greater than the first thickness of the first coating composition, with the proviso that the second coating composition does not overcoat the first coating composition and at least a portion of the first coating composition remains exposed.
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Abstract
The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable medical device, such as an intravascular stent, having a coating comprising a first coating composition comprising a therapeutic agent and, optionally, a polymer; and a second coating composition comprising a metallic material.
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Citations
22 Claims
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1. An implantable intravascular stent comprising:
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(a) a stent sidewall structure defining a surface; and (b) a coating comprising (i) a first coating composition formed of a material selected from the group consisting of one or more therapeutic agents and one or more polymers, the first coating composition contacting at least a portion of the surface of the stent sidewall structure wherein the first coating composition has a first thickness measured from the surface of the stent sidewall structure; and (ii) a second coating composition comprising a material different from the first coating composition, the second coating composition comprising a metallic material and being substantially free of any polymer, the second coating contacting at least a portion of the surface of the stent sidewall structure, at least a portion of the second coating composition being disposed adjacent to the first coating composition on the surface of the stent sidewall structure, wherein the second coating composition has a second thickness measured from the surface of the stent sidewall structure; and
wherein the second thickness of the second coating composition is the same as or greater than the first thickness of the first coating composition, with the proviso that the second coating composition does not overcoat the first coating composition and at least a portion of the first coating composition remains exposed. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification