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Pharmaceutical compositions and methods useful for modulating angiogenesis, inhibiting metastasis and tumor fibrosis, and assessing the malignancy of colon cancer tumors

  • US 8,815,823 B2
  • Filed: 03/09/2012
  • Issued: 08/26/2014
  • Est. Priority Date: 11/27/2002
  • Status: Expired due to Fees
First Claim
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1. A method of inhibiting angiogenesis in a subject, comprising:

  • administering to the subject a polynucleotide of at least 15 bases that specifically hybridizes under physiological conditions to a nucleic acid having the nucleotide sequence of SEQ ID NO;

    1,thereby inhibiting angiogenesis in the subject.

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