Methods for intravascularly-induced neuromodulation
First Claim
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1. A method for intravascularly-induced renal neuromodulation, the method comprising:
- intravascularly positioning a catheter comprising a balloon and a pair of bipolar electrodes within renal vasculature of a human patient;
expanding the balloon within the renal vasculature; and
delivering an electric field via the bipolar electrodes to induce renal neuromodulation,wherein inducing renal neuromodulation results in a therapeutically beneficial reduction in blood pressure of the patient.
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Abstract
Methods for intravascularly-induced renal neuromodulation. In some embodiments, a method can include positioning a pair of bipolar electrodes within renal vasculature of a human patient and expanding a balloon within the renal vasculature. The method can further include delivering an electric field via the bipolar electrodes.
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Citations
26 Claims
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1. A method for intravascularly-induced renal neuromodulation, the method comprising:
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intravascularly positioning a catheter comprising a balloon and a pair of bipolar electrodes within renal vasculature of a human patient; expanding the balloon within the renal vasculature; and delivering an electric field via the bipolar electrodes to induce renal neuromodulation, wherein inducing renal neuromodulation results in a therapeutically beneficial reduction in blood pressure of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for catheter-based renal denervation of a human patient, the method comprising:
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transluminally positioning a renal denervation catheter within a renal artery of the patient and adjacent to neural fibers that innervate a kidney of the patient, wherein the catheter includes a balloon and a pair of bipolar electrodes; inflating the balloon within the renal artery of the patient; and after inflating the balloon, at least partially ablating the neural fibers of the patient via energy from the bipolar electrodes, wherein at least partially ablating the neural fibers results in a therapeutically beneficial reduction in central sympathetic overactive of the patient. - View Dependent Claims (19, 20)
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21. A method for treating a human patient diagnosed with hypertension, the method comprising:
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positioning a catheter comprising a balloon and a pair of electrode poles within renal vasculature of the patient; expanding the balloon within the renal vasculature; and thermally inhibiting neural communication along neural fibers that innervate a kidney of the patient via an electric field from the electrode poles, wherein inhibiting the neural communication results in a therapeutically beneficial reduction in blood pressure of the patient. - View Dependent Claims (22, 23, 24, 25, 26)
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Specification