Fertility status diagnosis system

• US 8,821,407 B2
• Filed: 04/09/2012
• Issued: 09/02/2014
• Est. Priority Date: 07/01/2002
• Status: Expired due to Fees

• Current Assignee: Vaclav Kirsner
• Original Assignee: Vaclav Kirsner
• Inventors: Kirsner, Vaclav
• Primary Examiner(s): TOWA, RENE T
• Application Number:
  US13/442,699
• Publication Number:
  US 20120209138A1
• Time in Patent Office: 876 Days
• Field of Search: 600/304, 600/309, 600/313, 600/332, 600/367, 600/376, 600/547, 600/549, 600551-552, 600554-555, 600/557, 600570-571, 600/587, 600/591, 600/593
• US Class Current: 600/551
• CPC Class Codes: A61B 10/0012 Ovulation-period determination for animals A61D17/002
• CPC Class Codes: A61B 2010/0016 based on measurement of electric currents, e.g. conductivity tests

Abstract

Methods and apparatus for interpreting vaginal measurement data by electronic means without the need for the user to take part in the data interpretation process. More specifically, an intelligent probe monitors folliculogenesis and correlates the ovarian function data to probe profile characteristics of the female reproductive cycle. A fertile window is defined with reference to the correlation between folliculogenesis and probe cyclic profiles.

Claims

1. An apparatus for diagnosing fertility status, comprising:

a) a probe configured to insert into a vagina of a female mammal, wherein said probe inserted into said vagina monitors a biophysical variable to generate ovarian function data of a female reproductive cycle; and

b) a data analyzer which processes said ovarian function data to generate a probe cyclic profile, wherein preovulatory features of said probe cyclic profile include a first peak and a second peak which correspondingly define a first minimum, a second minimum and a third minimum, and wherein said data analyzer analyzes configuration of said first peak and said second peak in said preovulatory features of said probe cyclic profile to determine a beginning of a fertile window occurring in a descending part of said first peak at an amplitude about equal to said first minimum of said first peak.

2. The apparatus of claim 1, wherein ovulation in said female reproductive cycle corresponds with occurrence of said third minimum of said probe cyclic profile.

3. The apparatus of claim 2, wherein said data analyzer analyzes configuration of said first peak and said second peak in said preovulatory features of said probe cyclic profile to determine occurrence of said ovulation in said female reproductive cycle.

4. The apparatus of claim 1, wherein said data analyzer determines said end of said fertile window within said female reproductive cycle as occurring in said probe cyclic profile upon elapse of one day subsequent to said ovulation.

5. The apparatus of claim 1, wherein said data analyzer analyzes said ovarian function data to determine as to each day within said reproductive cycle whether said day is one of a fertile day or an infertile day.

6. The apparatus of claim 5, wherein said data analyzer assesses ovarian function data as occurring in postovulatory features of said probe cyclic profile after elapse of one day of said third minimum, and wherein said data analyzer determines said day to be said infertile day.

7. The apparatus of claim 5, wherein said data analyzer assesses ovarian function data as occurring in said preovulatory features of said probe cyclic profile before said first peak, and wherein said data analyzer determines said day to be said infertile day.

8. The apparatus of claim 5, wherein said data analyzer assesses ovarian function data as occurring in said preovulatory features of said probe cyclic profile more than one day before said second minimum, and wherein said data analyzer determines said day to be said infertile day.

9. The apparatus of claim 5, wherein said data analyzer assesses ovarian function data as occurring in said preovulatory features of said probe cyclic profile in a descending part of said first peak at an amplitude about equal to said first minimum of said first peak, and wherein said data analyzer determines said day to be said fertile day.

10. The apparatus of claim 5, wherein said data analyzer assesses ovarian function data as occurring in said probe cyclic profile between said beginning of said fertile window at a descending part of said first peak at an amplitude about equal to said first minimum of said first peak and said end of said fertile window at elapse of one day after said ovulation, and wherein said data analyzer determines said day to be said fertile day.

11. The apparatus of claim 10, wherein said data analyzer further includes a fertility threshold, and wherein said data analyzer assesses an amplitude in said preovulatory features of said probe cyclic profile greater than said fertility threshold, and wherein said data analyzer determines said day to be said infertile day.

12. The apparatus of claim 10, wherein said data analyzer further includes an ovulation threshold, and wherein said data analyzer assesses an amplitude in said postovulatory features of said probe cyclic profile greater than said ovulation threshold, and wherein said data analyzer determines said day to be said infertile day.

13. The apparatus of claim 12, wherein said data analyzer further includes a reliability analysis element which assesses reliability of determination of said fertile day or said infertile day within said female reproductive cycle based upon one or more of:

number of data points used in analysis, conception statistics for day of cycle, reproducibility of data upon repetition, amplitude of probe cyclic profile with respect to said fertility threshold and said ovulation threshold, and uncertainty as to day of said female reproductive cycle.