Infusion system

• US 8,821,442 B2
• Filed: 08/17/2009
• Issued: 09/02/2014
• Est. Priority Date: 02/24/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Haar, Hans-Peter
• Primary Examiner(s): Desanto, Matthew F
• Assistant Examiner(s): Zhang, Jenna
• Application Number:
  US12/542,047
• Publication Number:
  US 20100211011A1
• Time in Patent Office: 1,842 Days
• Field of Search: 604/131, 604151-155, 320124-128
• US Class Current: 604/151
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 2209/086 Docking stations
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/16854 by monitoring line pressure

Abstract

Disclosed is an infusion system for administering a liquid medicament, particularly insulin. Said infusion system comprises a cannula support unit which is properly attached to a patient'"'"'s body, an infusion cannula to be inserted into the patient'"'"'s body, and a pump unit that can be connected to the cannula support unit and encompasses a pump, a battery for supplying power to the pump, and a storage volume for the medicament that is to be administered. The pump unit and the cannula support unit are adapted to one another in such a way that the pump unit rests against the cannula support unit once the pump unit has been connected to the cannula support unit. The disclosed infusion system also comprises a charging station for the pump unit in order to recharge the battery of the pump unit.

Claims

1. An infusion system for administering a liquid medicinal agent, in particular insulin, comprising:

a cannula carrier unit comprising an upper side facing away from a body of a patient with a transfer cannula contained within the cannula carrier unit, an under side with an adhesive for directly securing the under side to the body of the patient and the under side is coupled to the transfer cannula, and an infusion cannula for puncturing into the body of the patient, the infusion cannula extending directly from the under side without being outside the perimeter of the under side;

a pump unit removably connected to the upper side of the cannula carrier unit using a positive-fit, the pump unit comprising a pump, a rechargeable battery for supplying energy to the pump, and a medicinal agent container being non-removable from the pump unit carried in a storage volume of the pump unit coupled to the transfer cannula, wherein the pump unit rests on the upper side of the cannula carrier unit after attachment of the pump unit to the cannula carrier unit; and

a charging station configured to receive the pump unit detached from the cannula carrier unit using a positive-fit to both recharge the rechargeable battery and refill the medicinal agent container with the liquid medicinal agent to be administered.

2. The infusion system according to claim 1, wherein the pump unit comprises two pump units configured to be charged in the charging station in an alternating manner.

3. The infusion system according to claim 1, wherein the charging station comprises a measuring device for determining an in vitro analyte concentration of a sample of body fluid.

4. The infusion system according to claim 1, wherein the pump unit has a pressure sensor for monitoring an infusion pressure of the liquid medicinal agent.

5. The infusion system according to claim 1, wherein the rechargeable battery is incorporated into the pump unit such as to be inaccessible for a user.

6. The infusion system according to claim 1, wherein the charging station is set up to take energy for charging the rechargeable battery of the pump unit coupled to the charging station from an internal energy storing facility.

7. The infusion system according to claim 1, wherein the pump unit has a sensor for monitoring the filling level of the storage volume.

8. The infusion system according to claim 1, wherein the storage volume comprises a refillable bellows bag for storing the liquid medicinal agent, the bellows bag comprises a front end with an opening for passage of the liquid medicinal agent and a back end with a coupling element for positive-fit coupling to a pump rod.

9. The infusion system according to claim 1, further comprising a refillable vial for storing the liquid medicinal agent, the refillable vial comprises a front end with an opening for passage of the liquid medicinal agent and a back end that is closed off by a shiftable plug, wherein a bellows is secured to the shiftable plug and protects internal walls of the vial from contamination when the shiftable plug is being pushed into the vial.

10. An infusion system for administering a liquid medicinal agent, in particular insulin, comprising:

two pump units, which each comprise a pump, a rechargeable battery, an a medicinal agent container that is non-removable carried in a storage volume of each pump unit, wherein each pump unit is removably attachable to a cannula carrier unit upper side using a positive-fit facing away from the body of a patient with a transfer cannula contained within the cannula carrier unit of the infusion system such that the pump rests on the cannula carrier unit after attachment of the pump unit to the cannula carrier unit; and

a charging station configured to receive each of the pump unit in an alternating manner such that when one of the pump unit is received in the charging station using a positive-fit, the charging station both recharge the rechargeable battery and refill the medicinal agent of the pump unit.

11. The infusion system according to claim 10, wherein the storage volume comprises a refillable bellows bag for storing a liquid medicinal agent, the bellows bag comprises a front end with an opening for passage of the medicinal agent and a back end with a coupling element for positive-fit coupling to a pump rod.

12. The infusion system according to claim 10, further comprising a refillable vial for storing a liquid medicinal agent, the refillable vial comprises a front end with an opening for passage of the medicinal agent and a back end that is closed off by a shiftable plug, wherein a bellows is secured to the plug and protects internal walls of the vial from contamination when the plug is being pushed into the vial.

13. The infusion system according to claim 10, wherein the cannula carrier unit is secured to the body of a patient and comprises an infusion cannula for puncturing into the body of the patient.

14. A rechargeable modular insulin infusion system having a fully enclosed infusion line wearable infusion pump, comprising:

a cannula carrier configured to be directly secured to a body of a patient with an adhesive;

an infusion cannula carried in the cannula carrier being a few centimeters long, the infusion cannula having a distal end positioned within the cannula carrier and a proximal end in the form of a hollow needle configured for puncturing the body of the patient wherein the proximal end extends directly from an under side of the cannula carrier without being outside the perimeter of the under side;

a pump unit removably connected to the cannula carrier using a positive-fit, the pump unit having a pump coupled to the infusion cannula distal end and a medicinal agent container non-removable from the pump unit carried in a storage volume of the pump unit having a replenishment connector, and the pump being electrically connected to a rechargeable battery having a recharging connector; and

a charging station configured to the pump unit removed from the cannula carrier using a positive-fit and both recharge the rechargeable battery and refill the medicinal agent container, the charging station comprising;

a plug connector for external power that is electrically coupled to a charging connector that is coupled to the recharging connector to recharge the rechargeable battery, and

a receiving compartment for a storage container containing the medicinal agent, and a charging pump for pumping the medical agent from the storage container into the medicinal agent container carried in the pump unit.

15. The rechargeable modular insulin infusion system as in claim 14 wherein the storage volume comprises two medicinal agent containers with each medicinal agent container holding less than or equal to a 12 hour supply of medicinal agent and configured so when one of the two medicinal agent containers is empty the medicinal agent container that is empty can be replaced during a window of time comprising less than 12 hours while the infusion system continues operating using the medicinal agent container that is not empty.

16. The rechargeable modular insulin infusion system as in claim 14 wherein the cannula carrier remains on the body of the patient while the pump unit is placed in the charging station to replenish the medicinal agent.