Device and a system for delivery of biological material

• US 8,821,447 B2
• Filed: 01/14/2011
• Issued: 09/02/2014
• Est. Priority Date: 06/06/2008
• Status: Expired due to Fees

• Current Assignee: Wockhardt Limited
• Original Assignee: Wockhardt Limited
• Inventors: Kodgule, Mandar, Yallambalsi, Sachidananda
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Hall, Deanna K
• Application Number:
  US13/006,489
• Publication Number:
  US 20110172610A1
• Time in Patent Office: 1,327 Days
• Field of Search: 604/173, 604/22, 604/272, 606/186
• US Class Current: 604/173
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/003 having a lumen
• CPC Class Codes: A61M 2037/0061 Methods for using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/2466 by piercing without internal pressure increase A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

The present invention provides a device and a system for the delivery of biological material across the biological tissue. The device may be for the programmed delivery of biological material through a needle or a micro-needle or micro-needles or biodegradable micro-needles.

Claims

1. A device for transport of biological materials across a biological barrier, wherein the device comprises a cartridge containing a fluid biological material, a needle cap and a single hollow micro-needle attached to a needle cap, wherein the said hollow micro-needle extends internally into the cartridge for establishing contact with the fluid biological material.

2. The device as claimed in claim 1, wherein the cross-sectional dimensions of micro-needle varies from about 1 μ

m to 500 μ

m and the length of the micro-needle is at least 100 μ

m.

3. The device as claimed in claim 1, wherein the micro-needle is made of one or more metals.

4. The device as claimed in claim 1, wherein the fluid biological material is selected from the group consisting of one or more of peptides, proteins, carbohydrates, nucleic acid molecules, lipids and other pharmaceutically active ingredients or combinations thereof.