Light-based implants for treating Alzheimer's disease

• US 8,821,559 B2
• Filed: 08/29/2005
• Issued: 09/02/2014
• Est. Priority Date: 08/27/2004
• Status: Expired

• Current Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Original Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Inventors: DiMauro, Thomas, Attawia, Mohamed, Lilienfeld, Sean, Holy, Chantal, Ward, Michael, Sutton, Jeffrey K
• Primary Examiner(s): ROANE, AARON F
• Application Number:
  US11/214,445
• Publication Number:
  US 20060100679A1
• Time in Patent Office: 3,291 Days
• Field of Search: 128/898, 607 88- 94
• US Class Current: 607/88
• CPC Class Codes: A61N 2005/063 comprising light transmitting means, e.g. optical fibres
• CPC Class Codes: A61N 2005/0651 Diodes
• CPC Class Codes: A61N 2005/0659 infrared
• CPC Class Codes: A61N 2005/0661 ultraviolet
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body

Abstract

An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer'"'"'s Disease.

Claims

1. A method of treating a patient having Alzheimer'"'"'s Disease, comprising the steps of:

a) providing a device comprising an LED and a fiber optic cable having a proximal end portion and a distal end portion;

b) implanting the device into the patient so that the distal end portion of the fiber optic cable is located adjacent to the hippocampus, and

c) delivering light provided in a wavelength of between 600 nm and about 1000 nm from the LED through the proximal end portion of the fiber optic cable to the distal end portion of the cable, and

d) irradiating the hippocampus with an effective amount of the delivered light,

wherein the fiber optic cable and LED are located inside the patient'"'"'s skull,

wherein the distal end portion of the fiber optic cable does not directly contact the hippocampus.

2. A method of treating a patient having Alzheimer'"'"'s Disease, comprising the steps of:

a) providing a device comprising an LED and a fiber optic cable having a proximal end portion and a distal end portion;

b) implanting the device into the patient so that the distal end portion of the fiber optic cable is located adjacent to the hippocampus, and

c) delivering light provided in a wavelength of between 650 nm and about 1000 nm from the LED through the proximal end portion of the fiber optic cable to the distal end portion of the cable, and

d) irradiating the hippocampus with an effective amount of the delivered light,

wherein the fiber optic cable and LED are located inside the patient'"'"'s skull,

wherein the distal end portion of the fiber optic cable does not directly contact the hippocampus.