Therapeutic methods and devices following myocardial infarction
First Claim
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1. A method for treating a chamber of a patient'"'"'s heart having a myocardial rupture or septal defect, comprising:
- identifying a region of the chamber of the patient'"'"'s heart exhibiting the myocardial rupture or septal defect;
delivering a device having a reinforced membrane to the patient'"'"'s heart chamber exhibiting the myocardial rupture or septal defect, the device being delivered to the patient'"'"'s heart chamber in an unexpanded configuration and the reinforced membrane having a distal facing side and a proximal facing side; and
deploying the device in the chamber of the patient'"'"'s heart by expanding the device to a deployed configuration within the heart chamber and with the distal facing side of the reinforced membrane facing the region of the chamber of the patient'"'"'s heart exhibiting the myocardial rupture or septal defect, wherein the device remains entirely within the chamber of the patient'"'"'s heart; and
isolating a portion of the chamber having the myocardial rupture or septal defect from a remainder of the chamber.
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Abstract
Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.
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Citations
22 Claims
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1. A method for treating a chamber of a patient'"'"'s heart having a myocardial rupture or septal defect, comprising:
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identifying a region of the chamber of the patient'"'"'s heart exhibiting the myocardial rupture or septal defect; delivering a device having a reinforced membrane to the patient'"'"'s heart chamber exhibiting the myocardial rupture or septal defect, the device being delivered to the patient'"'"'s heart chamber in an unexpanded configuration and the reinforced membrane having a distal facing side and a proximal facing side; and deploying the device in the chamber of the patient'"'"'s heart by expanding the device to a deployed configuration within the heart chamber and with the distal facing side of the reinforced membrane facing the region of the chamber of the patient'"'"'s heart exhibiting the myocardial rupture or septal defect, wherein the device remains entirely within the chamber of the patient'"'"'s heart; and isolating a portion of the chamber having the myocardial rupture or septal defect from a remainder of the chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for treating a chamber of a patient'"'"'s heart having a ventricular rupture or septal defect, comprising:
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identifying a region of a ventricle having the ventricular rupture or septal defect; delivering a partitioning device having a reinforced membrane to a patient'"'"'s ventricle exhibiting the ventricular rupture or septal defect; and deploying the partitioning device in the chamber of the patient'"'"'s ventricle, wherein the reinforced membrane is configured to form a recess in the reinforced membrane when the partitioning device is expanded to a deployed configuration; and partitioning the heart chamber into a productive portion and a nonproductive portion such that the ventricular rupture or septal defect is located in the nonproductive portion. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method for treating a chamber of a patient'"'"'s heart having a myocardial rupture or septal defect, comprising:
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identifying a region of a heart chamber wall surface exhibiting the myocardial rupture or septal defect; delivering to the patient'"'"'s heart chamber exhibiting the myocardial rupture or septal defect a device having a reinforced membrane and an outwardly biased strand secured to a periphery of the reinforced membrane; deploying the device in the chamber of the patient'"'"'s heart; sealing the periphery of the reinforced membrane to the heart chamber wall surface with the outwardly biased strand; and isolating the region of the chamber having the myocardial rupture or septal defect from a remaining portion of the chamber.
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Specification