Drug delivery device
First Claim
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1. An apparatus for delivering therapeutic fluid to a patient at an injection site, comprising:
- a fluid injection device having a housing, wherein the housing includes;
an injector for injecting the therapeutic fluid to a bodily tissue of the injection site; and
a reservoir for containing the therapeutic fluid; and
a treatment element comprising a heater coupled to the fluid injection device and configured to modify the temperature of the bodily tissue in a vicinity of the injection site to improve pharmacokinetic and/or pharmacodynamic property of the injected therapeutic fluid in the bodily tissue either a short time before, during and/or following injection of the therapeutic fluid into the patient, wherein the treatment element does not heat the therapeutic fluid above a predetermined limiting temperature.
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Abstract
The present disclosure presents systems, devices and methods for injection of drugs, substances and/or chemicals to a patient and for improving their effectiveness once they are injected are disclosed. Additional treatment can be applied to a tissue region on the patient into which a drug (e.g., insulin) is injected, to expose the tissue region to various forms of energy or a substance to improve the drug'"'"'s pharmacokinetic and/or pharmacodynamic profile.
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Citations
46 Claims
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1. An apparatus for delivering therapeutic fluid to a patient at an injection site, comprising:
a fluid injection device having a housing, wherein the housing includes;
an injector for injecting the therapeutic fluid to a bodily tissue of the injection site; and
a reservoir for containing the therapeutic fluid; and
a treatment element comprising a heater coupled to the fluid injection device and configured to modify the temperature of the bodily tissue in a vicinity of the injection site to improve pharmacokinetic and/or pharmacodynamic property of the injected therapeutic fluid in the bodily tissue either a short time before, during and/or following injection of the therapeutic fluid into the patient, wherein the treatment element does not heat the therapeutic fluid above a predetermined limiting temperature.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A method for delivering a therapeutic fluid to an injection site on a patient using a fluid delivery device having a fluid injection device having a housing, wherein the housing includes an injector for injecting the therapeutic fluid to a bodily tissue of the injection site and a reservoir for containing the therapeutic fluid, and a treatment element, comprising a heater, coupled to the fluid injection device and configured to apply treatment to the injection site, comprising the steps of:
- using the fluid injection device, injecting the therapeutic fluid at the injection site;
using the treatment element, applying a treatment to at least one of the injection site and adjacent the injection site, wherein the applying of the treatment element causes modification of the temperature of the bodily tissue in a vicinity of the injection site; and
improving, based on the applying of the treatment element, a pharmacokinetic and/or pharmacodynamic property of the therapeutic fluid upon application of the treatment. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
- using the fluid injection device, injecting the therapeutic fluid at the injection site;
Specification