Methods of treating traveler's diarrhea and hepatic encephalopathy
DCFirst Claim
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1. A method of treating a patient having hepatic encephalopathy (HE) comprising:
- identifying a subject having Travelers'"'"' Diarrhea (TD) that also has hepatic insufficiency;
determining if the subject'"'"'s Child-Pugh score is Child-Pugh Class C or if the subject'"'"'s model end stage liver disease (MELD) score is 25 or greater; and
administering between 1000 and 1200 mg of rifaximin daily and cautiously to the subject if the subject'"'"'s Child-Pugh score is Child-Pugh Class C or if the subject'"'"'s MELD score is 25 or greater.
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Abstract
Treatment of traveler'"'"'s diarrhea using in subjects having hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin.
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Citations
23 Claims
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1. A method of treating a patient having hepatic encephalopathy (HE) comprising:
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identifying a subject having Travelers'"'"' Diarrhea (TD) that also has hepatic insufficiency; determining if the subject'"'"'s Child-Pugh score is Child-Pugh Class C or if the subject'"'"'s model end stage liver disease (MELD) score is 25 or greater; and administering between 1000 and 1200 mg of rifaximin daily and cautiously to the subject if the subject'"'"'s Child-Pugh score is Child-Pugh Class C or if the subject'"'"'s MELD score is 25 or greater. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method of treating a patient suffering from hepatic encephalopathy (HE) comprising:
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identifying a subject having Traveler'"'"'s Diarrhea (TD) that also has HE; determining the severity of the subject'"'"'s HE; and administering between 1000 and 1200 mg of rifaximin daily and cautiously to the subject if the HE is severe. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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Specification