Fiducial-less tracking of a volume of interest
First Claim
Patent Images
1. A method comprising:
- generating, by a processing device, a plurality of digitally reconstructed radiograph (DRR) pairs from a plurality of volumes of four dimensional (4D) diagnostic imaging data showing a movable bony structure and a static bony structure of a patient, the generating comprising;
segmenting an image of the static bony structure from each of the plurality of volumes of 4D diagnostic imaging data, wherein the image of the static bony structure obstructs a view of the movable bony structure; and
removing the image of the static bony structure from the plurality of DRR pairs;
generating a pair of intra-operative images of a portion of the patient during treatment of a target region in the patient to show the movable bony structure of the patient, wherein the movable bony structure moves responsive to respiration of the patient;
comparing the pair of intra-operative images with the plurality of DRR pairs;
correlating a location of the movable bony structure in a particular volume of the plurality of volumes of 4D diagnostic imaging data with a location of the target region in the particular one of the plurality of volumes of 4D diagnostic imaging data, based on the comparing, to determine an intra-operative location of the target region in the patient using only the movable bony structure, wherein the 4D diagnostic imaging data shows the location of the target region; and
directing a treatment beam at the patient based on determining the intra-operative location of the target region.
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Abstract
A method and an apparatus for fiducial-less tracking of a volume of interest (VOI) have been presented. In some embodiments, a pair of intra-operative images of a portion of a patient is generated during treatment of a target region in the patient to show a bony structure of the patient. The bony structure shown is movable responsive to respiration of the patient. Then the pair of intra-operative images is compared with a set of digitally reconstructed radiograph (DRR) pairs, generated from volumes of four-dimensional (4D) diagnostic imaging data, to determine a location of the movable bony structure that corresponds to a particular volume of the 4D diagnostic imaging data.
31 Citations
14 Claims
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1. A method comprising:
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generating, by a processing device, a plurality of digitally reconstructed radiograph (DRR) pairs from a plurality of volumes of four dimensional (4D) diagnostic imaging data showing a movable bony structure and a static bony structure of a patient, the generating comprising; segmenting an image of the static bony structure from each of the plurality of volumes of 4D diagnostic imaging data, wherein the image of the static bony structure obstructs a view of the movable bony structure; and removing the image of the static bony structure from the plurality of DRR pairs; generating a pair of intra-operative images of a portion of the patient during treatment of a target region in the patient to show the movable bony structure of the patient, wherein the movable bony structure moves responsive to respiration of the patient; comparing the pair of intra-operative images with the plurality of DRR pairs; correlating a location of the movable bony structure in a particular volume of the plurality of volumes of 4D diagnostic imaging data with a location of the target region in the particular one of the plurality of volumes of 4D diagnostic imaging data, based on the comparing, to determine an intra-operative location of the target region in the patient using only the movable bony structure, wherein the 4D diagnostic imaging data shows the location of the target region; and directing a treatment beam at the patient based on determining the intra-operative location of the target region. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A non-transitory machine-readable storage medium that provides instructions that, when executed by a processing device, performs operations comprising:
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generating, by the processing device, a plurality of digitally reconstructed radiograph (DRR) pairs from a plurality of volumes of four dimensional (4D) diagnostic imaging data showing a movable bony structure and a static bony structure of a patient, the generating comprising; segmenting an image of the static bony structure from each of the plurality of volumes of 4D diagnostic imaging data, wherein the image of the static bony structure obstructs a view of the movable bony structure; and removing the image of the static bony structure from the plurality of DRR pairs; generating a pair of intra-operative images of a portion of the patient during treatment of a target region in the patient to show the movable bony structure of the patient, wherein the movable bony structure moves responsive to respiration of the patient; and comparing the pair of intra-operative images with the plurality of DRR pairs; correlating a location of the movable bony structure in a particular volume of the plurality of volumes of 4D diagnostic imaging data with a location of the target region in the particular one of the plurality of volumes of 4D diagnostic imaging data, based on the comparing, to determine an intra-operative location of the target region in the patient using only the movable bony structure, wherein the 4D diagnostic imaging data shows the location of the target region; and directing a treatment beam at the patient based on determining the intra-operative location of the target region. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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Specification