Indicator for fluid resuscitation

• US 8,834,379 B2
• Filed: 03/25/2011
• Issued: 09/16/2014
• Est. Priority Date: 03/26/2010
• Status: Active Grant

• Current Assignee: Dragerwerk AG & Company KGaA (FPS Vermögensverwaltung GmbH)
• Original Assignee: Drager Medical GmbH (FPS Vermögensverwaltung GmbH)
• Inventors: Van Houwelingen, Marc
• Primary Examiner(s): Kahelin, Michael
• Assistant Examiner(s): TRAN, THO Q
• Application Number:
  US13/071,983
• Publication Number:
  US 20110237959A1
• Time in Patent Office: 1,271 Days
• Field of Search: 600/484, 600/533, 600/529, 600/485, 600/481, 128/200.24, 128/200.18, 128/204.23
• US Class Current: 600/484
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/091 Measuring volume of inspired or expired gases, e.g. to determine lung capacity
• CPC Class Codes: A61M 16/00 Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes stimulating the respiratory movement by mechanical, pneumatic or electrical means, iron lungs combined with gas breathing means A61H31/00
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0084 self-reinflatable by elasticity, e.g. resuscitation squeeze bags
• CPC Class Codes: A61M 16/021 operated by electrical means A61M16/202 – A61M16/205 take precedence

Abstract

A system for providing an indication of cardiovascular function, includes a respiration input (1) for receiving a respiration-related signal indicative of a physical property of respiration gases administered to a patient. A hemodynamic input (2) is provided for receiving a hemodynamic-related signal indicative of a hemodynamic property. An inspiration detector (3) is provided for processing the respiration-related signal to detect times of inspiration and a measure of the size of the inspiration. A correlator (5) is provided for correlating the sizes of inspiration with the hemodynamic-related signal, to obtain the indication of cardiovascular function. The respiration-related signal is indicative of inspiration pressure, inspiration volume, or inspiration flow. The hemodynamic-related signal is indicative of blood pressure.

Claims

1. A system for providing an indication of cardiovascular function, the system comprising:

a respiration input for receiving a respiration-related signal indicative of a physical property of respiration gases administered to a patient;

a hemodynamic input for receiving a hemodynamic-related signal indicative of a hemodynamic property;

an inspiration detector for processing the respiration-related signal to detect times of inspiration and a measure of a size of inspiration;

a correlator for correlating the sizes of inspiration with the hemodynamic-related signal, to obtain the indication of cardiovascular function;

a variance detector for determining a variance in the size of inspiration of successive inspirations; and

a threshold means for comparing the variance of the size of inspiration with a threshold, wherein the correlator obtains the indication of cardiovascular function only if the variance exceeds the threshold.

2. A system according to claim 1, wherein the respiration-related signal is indicative of inspiration pressure, inspiration volume, or inspiration flow.

3. A system according to claim 1, wherein the hemodynamic-related signal is indicative of blood pressure.

4. A system according to claim 1, wherein the system automatically performs the processing, the determining, and the correlating based on newly received data while the respiration-related signal and the hemodynamic-related signal are being received.

5. A system according to claim 1, further comprising a display for displaying the indication of cardiovascular function.

6. A system according to claim 1, wherein the system handles a respiration-related signal indicative of nonmonotonically varying sizes of the inspiration in successive inspirations.

7. A system according to claim 1, further comprising:

a device comprising a blood pressure sensor for generating the hemodynamic-related signal and a respiration sensor for generating the respiration-related signal, wherein the respiration sensor is in fluid communication with a connector for connecting a measurement hose.

8. A system according to claim 1, wherein said variance corresponds to a variability of sizes of said successive inspirations in a given time span, said comparison of said variance of said size of inspiration with said threshold providing an indication as to whether an accurate cardiovascular function is obtainable from said respiration-related signal and said hemodynamic-related signal.

9. A device for providing mechanical ventilation to a patient, the device comprising

a handbag for manually administering air to a patient;

a respiration related sensor for generating a respiration-related signal indicative of a physical property of respiration gases administered to a patient, wherein the respiration-related signal is for a system for providing an indication of cardiovascular function, the system comprising a respiration input for receiving the respiration-related signal indicative of a physical property of respiration gases administered to a patient, a hemodynamic input for receiving a hemodynamic-related signal indicative of a hemodynamic property, an inspiration detector for processing the respiration-related signal to detect times of inspiration and a measure of a size of inspiration and a correlator for correlating the sizes of inspiration with the hemodynamic-related signal, to obtain the indication of cardiovascular function, said system further comprising a variance detector for determining a variance in the size of inspiration of successive inspirations and a threshold means for comparing the variance of the size of inspiration with a threshold, wherein the correlator obtains the indication of cardiovascular function only if the variance exceeds the threshold.

10. A device according to claim 9, wherein the respiration-related signal is indicative of inspiration pressure, inspiration volume, or inspiration flow.

11. A device according to claim 10, wherein the hemodynamic-related signal is indicative of blood pressure.

12. A device according to claim 11, wherein the system automatically performs the processing, the determining, and the correlating based on newly received data while the respiration-related signal and the hemodynamic-related signal are being received.

13. A device according to claim 12, further comprising a display for displaying the indication of cardiovascular function.

14. A device according to claim 12, wherein the system handles a respiration-related signal indicative of nonmonotonically varying sizes of the inspiration in successive inspirations.

15. A device according to claim 9, further comprising a device for generating the hemodynamic-related signal, wherein the respiration sensor is in fluid communication with a connector for connecting a measurement hose.

16. A device according to claim 9, wherein said variance corresponds to a variability of sizes of said successive inspirations in a given time span, said comparison of said variance of said size of inspiration with said threshold providing an indication as to whether an accurate cardiovascular function is obtainable from said respiration-related signal and said hemodynamic-related signal.

17. A method of providing an indication of cardiovascular function, the method comprising the steps of:

receiving a respiration-related signal indicative of a physical property of respiration gases administered to a patient;

receiving a hemodynamic-related signal indicative of a hemodynamic property;

processing the respiration-related signal to detect times of inspiration and a measure of the size of the inspiration;

determining a variance in the size of inspiration of successive inspirations;

comparing the variance of the size of inspiration with a threshold;

correlating the sizes of inspiration with the hemodynamic-related signal, to obtain the indication of cardiovascular function only if said variance exceeds said threshold;

providing a processor system and a computer program product comprising instructions for causing the processor system to perform the steps of receiving the respiration-related signal, receiving the hemodynamic-related signal, processing the respiration-related signal and correlating the sizes of inspiration with the hemodynamic-related signal.

18. A method according to claim 17, wherein said variance corresponds to a variability of sizes of said successive inspirations in a given time span, wherein said comparison of said variance of said size of inspiration with said threshold provides an indication as to whether an accurate cardiovascular function is obtainable from said respiration-related signal and said hemodynamic-related signal.

19. A method according to claim 17, wherein said variance corresponds to a maximal difference between any two sizes or a standard deviation of said sizes of inspiration of said successive inspirations.