Method and device for effecting anastomosis of hollow organ structures using adhesive and fasteners

• US 8,834,498 B2
• Filed: 11/10/2006
• Issued: 09/16/2014
• Est. Priority Date: 11/10/2006
• Status: Active Grant

• Current Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Byrum, Randal T., Gill, Robert P., Kelly, William D., Kolata, Ronald J., Ortiz, Mark S., Shelton, Frederick E. IV, Turner, Douglas J., Voegele, James W.
• Primary Examiner(s): Dornbusch, Dianne
• Assistant Examiner(s): ORKIN, ALEXANDER J
• Application Number:
  US11/558,572
• Publication Number:
  US 20080114385A1
• Time in Patent Office: 2,867 Days
• Field of Search: 606/153, 606/154, 606/151
• US Class Current: 606/153
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0643 with separate closing member, e.g. for interlocking with staple
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 17/1114 of the digestive tract, e.g. bowels or oesophagus
• CPC Class Codes: A61B 17/115 Staplers for performing anastomosis in a single operation
• CPC Class Codes: A61B 17/1155 Circular staplers comprising a plurality of staples
• CPC Class Codes: A61B 17/1227 Spring clips
• CPC Class Codes: A61B 17/1285 for minimally invasive surgery
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/0641 having at least three legs as part of one single body
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11

Abstract

A method and devices for accomplishing the successful anastomosis of two hollow organ structures are disclosed. The method includes bringing the structures together, applying at least one fastener to hold the structures together and form a connection site, and applying, as alternatives or in conjunction, an adhesive, a wrap and/or a buttress about the connection site. Various examples of fasteners, fastener appliers, adhesives, adhesive initiators and buttress rings also are disclosed.

Claims

1. A method for effecting an anastomosis of a first and second hollow tubular organ structure, each hollow tubular organ structure having a severed end and an outside perimeter that defines a lumen in each hollow tubular organ structure, the method comprising:

placing a bead of material comprising adhesive around an edge of the severed end of the first hollow tubular organ structure;

placing a bead of material comprising adhesive initiator around an edge of the severed end of the second hollow tubular structure;

bringing the severed ends of said hollow tubular organ structures together such that the beads of material of said first and second hollow tubular organ structure meet to form an adhesive deposit and seal the connection of said first and second hollow tubular organ structures;

providing at least one transformable fastener, wherein the at least one transformable fastener comprises a pair of deformable ends operably configured to hold said hollow tubular organ structures together;

providing an applier operable to apply said at least one transformable fastener, wherein the applier comprises;

a first fastener transforming member having a first surface, wherein the first fastener transforming member contacts one of the pair of deformable ends of the at least one transformable fastener;

a second fastener transforming member having a second surface, wherein the second fastener transforming member contacts another one of the pair of deformable ends of the at least one transformable fastener; and

a mechanism holding said first fastener transforming member and said second fastener transforming member in operable positions with respect to each other;

wherein said mechanism may be actuated so as to cause said first surface to move toward said second surface, and during actuation said first and second surfaces exert at least partially opposing forces that cause transformation of said at least one transformable fastener such that the deformable ends face away from the longitudinal axis of the applier;

using said applier to apply said at least one transformable fastener to hold the severed ends of said hollow tubular organ structures together resulting in a connection of the severed ends and merging of the beads of material, thereby forming a connection site where said two hollow tubular organ structures are held together; and

placing a wrap comprising a hydrophilic material, a therapeutic material, and a dry adhesive over at least a portion of said connection site, wherein the dry adhesive is configured to be activated by one or both of contact with water drawn from the tissues or an initiator applied by a user and wherein the dry adhesive comprises a 1,1-disubstituted ethylene monomer.

2. The method of claim 1 wherein said wrap further comprises a material selected from the group consisting of an accelerator and an additive.

3. The method of claim 1 wherein said at least one transformable fastener comprises a material selected from the group consisting of a bioabsorbable material and a degradable material.