Method and device for left atrial appendage occlusion

• US 8,834,519 B2
• Filed: 11/18/2011
• Issued: 09/16/2014
• Est. Priority Date: 11/06/1998
• Status: Expired due to Fees

• Current Assignee: Artritech Incorporated
• Original Assignee: Artritech Incorporated
• Inventors: van der Burg, Erik J., De Cicco, Dino, Frazier, Andrew G. C., Khairkhahan, Alexander K., Kreidler, Marc S., Lesh, Michael D., Roue, Chad C.
• Primary Examiner(s): Erezo, Darwin
• Assistant Examiner(s): HOLLM, JONATHAN A
• Application Number:
  US13/299,796
• Publication Number:
  US 20120065662A1
• Time in Patent Office: 1,033 Days
• Field of Search: 606/151, 606/157, 606/200, 606/213
• US Class Current: 606/213
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/12195 comprising a curable material
• CPC Class Codes: A61B 17/122 Clamps or clips , e.g. for the umbilical cord for the vas deferens A61F6/206
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00557 inflatable A61B2017/22051 takes precedence
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00579 Barbed implements
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/00601 Implements entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2017/00615 Implements with an occluder on one side of the opening and holding means therefor on the other
• CPC Class Codes: A61B 2017/00619 Locking means for locking the implement in expanded state
• CPC Class Codes: A61B 2017/00632 Occluding a cavity, i.e. closing a blind opening
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/081 : Tissue approximator A61B2017/1103, A61B17/8866 take precedence
• CPC Class Codes: A61B 2017/1205 : Introduction devices
• CPC Class Codes: A61F 2/01 : Filters implantable into blood vessels
• CPC Class Codes: A61F 2002/018 : made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 : circular
• CPC Class Codes: A61F 2230/0069 : cylindrical
• CPC Class Codes: A61F 2230/0071 : spherical
• CPC Class Codes: A61F 2230/008 : paraboloidal
• CPC Class Codes: A61M 2025/1054 : having detachable or disposable balloons
• CPC Class Codes: A61M 2210/125 : Heart
• CPC Class Codes: A61M 25/10 : Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00

Abstract

A device and method for obliterating or occluding a body cavity or passageway, in particular, the left atrial appendage of a patient'"'"'s heart. The procedure can be carried out intraoperatively, but is preferably carried out percutaneously by use of a delivery catheter to position an occluding device adjacent a patient'"'"'s left atrial appendage. The occluding device may prevent the passage of embolic or other material to or from the left atrial appendage by volumetrically filling the appendage, closing the opening of the appendage with an occluding member, or pulling the tissue around the opening of the appendage together and fixing it in a closed state.

Claims

1. A method of preventing passage of embolic material from a left atrial appendage, comprising:

advancing a catheter having a proximal end and a distal end through the patient until the distal end is disposed adjacent the opening of the patient'"'"'s left atrial appendage; and

releasing a device from the distal end of the catheter to deploy the device within the left atrial appendage, the device configured to block an opening to the left atrial appendage to prevent passage of embolic material from the left atrial appendage.

2. The method of claim 1, wherein the device is positioned within an inner lumen of the catheter, and releasing the device comprises applying axial force in a distal direction to the device to deploy it.

3. The method of claim 1, wherein the device is biased to a radially expanded position, and wherein the device radially expands within the left atrial appendage during the releasing step.

4. The method of claim 1, wherein the device is biased to press against an inner wall of the left atrial appendage subsequent to the releasing step.

5. The method of claim 1, wherein releasing the device from the catheter comprises detaching the device from the distal end of the catheter.

6. The method of claim 1, wherein the device comprises an expandable frame.

7. The method of claim 6, wherein the device comprises a barrier membrane attached to the expandable frame.

8. The method of claim 7, wherein the barrier membrane comprises a mesh material.

9. The method of claim 6, wherein the expandable frame comprises a plurality of strut members.

10. The method of claim 9, wherein the barrier membrane envelopes at least a proximal portion of the plurality of strut members.

11. The method of claim 9, wherein the barrier membrane comprises a proximal portion and a distal portion and wherein the distal portion is cylindrical.

12. The method of claim 6, wherein the expandable frame, when expanded, has a first portion that extends proximally and a second portion, attached to the first portion, that extends distally.

13. The method of claim 12, wherein the first portion extends radially outwardly.

14. The method of claim 13, wherein the second portion is substantially cylindrical.

15. The method of claim 12, wherein the expandable frame comprises a central hub attached to the first portion.

16. The method of claim 15, wherein the hub comprises a lumen.