Signal processing warping technique

• US 8,840,562 B2
• Filed: 09/13/2010
• Issued: 09/23/2014
• Est. Priority Date: 09/24/2009
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: McKenna, Edward M., Peters, Daniel Jon
• Primary Examiner(s): Cheng, Jacqueline
• Assistant Examiner(s): Agahi, Puya
• Application Number:
  US12/880,306
• Publication Number:
  US 20110071378A1
• Time in Patent Office: 1,471 Days
• Field of Search: 600/364, 600/365, 600/368, 600500-504, 600/301, 600/336
• US Class Current: 600/500
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/6816 Ear lobe
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/726 using Wavelet transforms
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

Methods and systems are provided for using time-frequency warping to analyze a physiological signal. One embodiment includes applying a warping operator to the physiological signal based on the energy density of the signal. The warped physiological signal may be analyzed to determine whether non-physiological signal components are present. Further, the same warping operator may be applied to signal quality indicators, and the warped physiological signal may be analyzed based on the warped signal quality indicators. Non-physiological signal components, or types of non-physiological noise sources, may be identified based on a comparison of the physiological signal with the signal quality indicators. Non-physiological signal components may also be identified based on a neural network of known noise functions. In some embodiments, the non-physiological signal components may be removed to increase accuracy in estimating physiological parameters.

Claims

1. A method for measuring a physiological parameter of a human, comprising the acts of:

analyzing, by using a processor, an energy density of a signal having a physiological component and a non-physiological component to determine one or more changes in the energy density of the signal over time;

determining, by using the processor, based on the one or more changes in the energy density of the signal over time, a warping function configured to enable identification of characteristics of the signal corresponding to the non-physiological component;

stretching or compressing along a time scale, by using the processor, the signal having the physiological component and the non-physiological component by using the warping function to produce a warped signal;

stretching or compressing, by using the processor, a signal quality indicator by using the warping function to produce a warped signal quality indicator;

identifying, by using the processor, the non-physiological component of the signal based on an analysis of the warped signal with the warped signal quality indicator; and

using the physiological component of the signal and disregarding the non-physiological component of the signal to determine the physiological parameter.

2. The method, as set forth in claim 1, comprising warping a signal quality indicator with the warping function, and wherein identifying the non-physiological signal component is based on an analysis of the warped signal and a warped signal quality indicator.

3. The method, as set forth in claim 2, wherein the signal quality indicator comprises one or more signals derived from known physiological and non-physiological signal characteristics.

4. The method, as set forth in claim 2, wherein the signal quality indicator comprises one or more signals indicative of optical interference, undesired light modulation, physical movement of a patient, or improper sensor placement.

5. The method, as set forth in claim 1, wherein the signal comprises a plethysmographic signal or a spectrogram corresponding to the plethysmographic signal.

6. The method, as set forth in claim 1, comprising indicating the presence of the non-physiological component on a pulse oximeter measuring the signal.

7. The method, as set forth in claim 1, comprising indicating a source of the non-physiological component on a pulse oximeter measuring the signal.

8. The method, as set forth in claim 1, comprising using the non-physiological component in a neural network and identifying future occurrences of the non-physiological component based on the neural network.

21. The method, as set forth in claim 1, wherein analyzing the energy density of the signal comprises characterizing the signal over a time-frequency plane to generate a three dimensional time-frequency representation of the signal, and analyzing the three dimensional time-frequency representation of the signal to determine the spectral density of the signal with respect to time and frequency.

9. A method for measuring a physiological parameter of a human, comprising the acts of:

analyzing, by using a processor, an energy density of a signal having a physiological component and a non-physiological component to determine one or more changes in the energy density of the signal over time;

determining, by using the processor, based on the one or more changes in the energy density of the signal over time, a warping function configured to enable identification of characteristics of the signal corresponding to the non-physiological component;

stretching or compressing along a time scale, by using the processor, the signal having the physiological component and the non-physiological component by using the warping function to produce a warped signal;

stretching or compressing along a time scale, by using the processor, a signal quality indicator by using the warping function to produce a warped signal quality indicator;

analyzing, by using the processor, the warped signal and the warped signal quality indicator;

identifying, by using the processor, the non-physiological component of the signal based on the analysis of the warped signal and the warped signal quality indicator; and

using the physiological component of the signal and disregarding the non-physiological component of the signal to determine the physiological parameter.

10. The method, as set forth in claim 9, wherein analyzing the warped signal and the warped signal quality indicator comprises analyzing the two signals in a common time scale.

11. The method, as set forth in claim 10, wherein analyzing the warped signal and the warped signal quality indicator comprises cross-correlating the two signals.

12. The method, as set forth in claim 11, wherein identifying the non-physiological component comprises determining whether a cross-correlation of the two signals indicates a non-physiological component.

13. The method, as set forth in claim 12, wherein the non-physiological component is identifiable based on whether a portion of the cross-correlation surpasses a threshold.

14. The method, as set forth in claim 9, wherein identifying the non-physiological signal component comprises comparing a scalogram of the warped signal with a scalogram of the warped signal quality indicator.

15. A pulse oximetry system, comprising:

data processing circuitry configured to;

analyze a three dimensional time-frequency representation of a signal comprising a physiological component and a non-physiological component to determine one or more changes in the energy density of the signal over time, to determine, based on the one or more changes in the energy density of the signal over time, a warping operator configured to enable identification of the non-physiological component;

warp the signal, via the processor, with the warping operator to produce a warped signal;

warp a signal quality indicator, via the processor, with the warping operator to produce a warped signal quality indicator;

identify the non-physiological component of the signal based on a comparison of the warped signal and the warped signal quality indicator; and

determine a physiological parameter by disregarding the non-physiological component of the signal and by using the physiological component of the signal.

16. The pulse oximetry system of claim 15, wherein the signal comprises a plethysmographic signal or a spectrogram corresponding to the plethysmographic signal.

17. The pulse oximetry system of claim 15, wherein the data processing circuitry is further configured to warp a signal quality indicator with the warping operator to produce a warped signal quality indicator.

18. The pulse oximetry system of claim 17, wherein the data processing circuitry is configured to compare the warped signal and the warped signal quality indicator to identify the non-physiological component of the signal.

19. The pulse oximetry system of claim 15, wherein the warping operator comprises an operator for stretching the signal along the time scale or a compressing operator for compressing the signal along the time scale.

20. The pulse oximetry system of claim 15, comprising a display on which the data processing circuitry displays an indication of the type or presence of the identified non-physiological component.