Cochlear implant using optical stimulation with encoded information designed to limit heating effects

• US 8,840,654 B2
• Filed: 07/21/2012
• Issued: 09/23/2014
• Est. Priority Date: 07/22/2011
• Status: Active Grant

• Current Assignee: Nurotone Medical Ltd.
• Original Assignee: Lockheed Martin Corporation (Martin Marietta Corporation)
• Inventors: Stafford, Ryan C., Stafford, James W.
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): PAHAKIS, MANOLIS Y
• Application Number:
  US13/555,095
• Publication Number:
  US 20130023963A1
• Time in Patent Office: 794 Days
• Field of Search: 607/137, 607 88- 89
• US Class Current: 607/89
• CPC Class Codes: A61N 1/0541 Cochlear electrodes
• CPC Class Codes: A61N 1/36039 fitting procedures
• CPC Class Codes: A61N 2005/0605 Ear
• CPC Class Codes: A61N 2005/0626 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 2005/0659 infrared
• CPC Class Codes: A61N 5/0622 Optical stimulation for exciting neural tissue
• CPC Class Codes: A61N 5/067 using laser light
• CPC Class Codes: F04C 2270/0421 Controlled or regulated

Abstract

Method and apparatus for optically stimulating neurons of a plurality of auditory nerve pathways of a person to provide auditory sensations for the person by generating a plurality of pulsed light signals having one or more successive pulses. The spectrum of a detected audio signal is divided into M channels. In some embodiments, an N-of-M coding strategy is employed, where, for any given time frame, only N of the M channels are selected and illuminated to stimulate the auditory nerves. In some embodiments, the M channels are organized into bins, where, for any given time frame, only a maximum number of channels are illuminated per bin. This limits the number of illuminated channels-per-length of cochlea and therefore prevents localized heating of the cochlea and reduces power consumption of the device.

Claims

1. An apparatus for optically stimulating neurons of a cochlea of a person, the apparatus comprising:

means for obtaining an audio signal having an audio spectrum;

means for generating a plurality of “

M”

audio channels of the audio spectrum for each of a plurality of successive time frames including a first, second, third and fourth time frame, each of the plurality of “

M”

audio channels for one of the plurality of time frames having a sub-portion of frequencies of the audio spectrum for a period of time corresponding to that one of the plurality of frames;

means for selecting for each of the plurality of time frames a subset of “

N”

audio channels selected from the “

M”

audio channels by an “

N of M”

coding strategy, wherein “

M” and

“

N”

are variables representing numbers of audio channels, wherein the “

M”

audio channels are divided into a plurality of bins including a first bin, a second bin, and a third bin, wherein the first bin includes a first plurality of adjacent audio channels of the “

M”

audio channels, wherein the second bin includes a second plurality of adjacent audio channels of the “

M”

audio channels, wherein the first plurality of adjacent audio channels and the second plurality of adjacent audio channels are mutually exclusive, wherein the third bin includes a third plurality of adjacent audio channels of the “

M”

audio channels, wherein the third plurality of adjacent audio channels partially overlaps the first plurality of adjacent audio channels and the second plurality of adjacent audio channels, wherein the means for selecting a subset of “

N”

audio channels includes a means for placing a quota on a maximum number of channels activated within each of the plurality of bins during each of the plurality of time frames in order to prevent localized overheating of the cochlea, wherein the quota is fewer than all channels within each of the plurality of bins;

means for generating for each of the plurality of time frames a corresponding pulsed light signal having one or more successive pulses for each one of the subset of “

N”

audio channels that, when applied to a neuron of a person, will each stimulate a nerve action potential (NAP) in the neuron; and

means for delivering for each of the plurality of time frames the generated corresponding pulsed light signals to a corresponding one of a plurality of frequency-specific locations in the cochlea of the person to optically stimulate one or more neurons in the cochlea in order to trigger NAPs in the one or more neurons of the cochlea.

2. The apparatus of claim 1, and wherein a first frequency range covered by the adjacent audio channels in the first bin partially overlaps with a second frequency range covered by adjacent audio channels in the third bin.

3. The apparatus of claim 1, wherein the means for selecting the subset of “

N”

audio channels includes selecting an individual one of the “

M”

audio channels at no more than two successive time frames during the plurality of successive time frames.

4. The apparatus of claim 1, wherein the means for selecting is further configured to select the subset of “

N”

audio channels, such that an individual one of the “

M”

audio channels is selected at no more than two successive time frames during the plurality of successive time frames.

5. The apparatus of claim 1, wherein the means for selecting is further configured to select the subset of “

N”

audio channels during the first time frame such that eleven audio channels corresponding to eleven portions of the audio spectrum having a strongest signal are selected from the “

M”

audio channels during the first time frame, and wherein the first time frame is in a range of approximately 4 milliseconds to 7.5 milliseconds.

17. The apparatus of claim 1, wherein the means for generating for each of the plurality of time frames a corresponding pulsed light signal includes a vertical-cavity surface emitting laser (VCSEL).

18. The apparatus of claim 1, wherein the means for generating for each of the plurality of time frames a corresponding pulsed light signal includes a plurality of vertical-cavity surface emitting lasers (VCSELs) arranged in an array.

6. An apparatus for optically stimulating neurons of a cochlea of a person, the apparatus comprising:

an audio sensor configured to obtain an audio signal having an audio spectrum;

an audio processor configured to generate a plurality of “

M”

audio channels of the audio spectrum for each of a plurality of successive time frames including a first, second, third and fourth time frame, each of the plurality of “

M”

audio channels for one of the plurality of time frames having a sub-portion of frequencies of the audio spectrum for a period of time corresponding to that one of the plurality of frames;

a channel mapper configured to select for each of the plurality of time frames a subset of “

N”

audio channels selected from the “

M”

audio channels by an “

N of M”

coding strategy, wherein “

M” and

“

N”

are variables representing numbers of audio channels, wherein the “

M”

audio channels are divided into a plurality of bins including a first bin, a second bin, and a third bin, wherein the first bin includes a first plurality of adjacent audio channels of the “

M”

audio channels, wherein the second bin includes a second plurality of adjacent audio channels of the “

M”

audio channels, wherein the first plurality of adjacent audio channels and the second plurality of adjacent audio channels are mutually exclusive, wherein the third bin includes a third plurality of adjacent audio channels of the “

M”

audio channels, wherein the third plurality of adjacent audio channels partially overlaps the first plurality of adjacent audio channels and the second plurality of adjacent audio channels, wherein the channel mapper places a quota on a maximum number of channels activated within each of the plurality of bins during each of the plurality of time frames in order to prevent localized overheating of the cochlea, wherein the quota is fewer than all channels within each of the plurality of bins;

an optical generator configured to output, for each of the plurality of time frames, a corresponding pulsed light signal having one or more successive pulses for each one of the subset of “

N”

audio channels that, when applied to a neuron of a person, will each stimulate a nerve action potential (NAP) in the neuron; and

an optical guide configured to deliver, for each of the plurality of time frames, the generated corresponding pulsed light signals to a corresponding one of a plurality of frequency-specific locations in the cochlea of the person to optically stimulate one or more neurons in the cochlea in order to trigger NAPs in the one or more neurons of the cochlea.

7. The apparatus of claim 6, wherein adjacent ones of the audio channels of the plurality of audio channels in each bin are directed towards neurons that, when triggered, are perceived by the person to be adjacent to each other in frequency.

8. The apparatus of claim 7, and wherein a first frequency range covered by the adjacent audio channels in the first bin partially overlaps with a second frequency range covered by adjacent audio channels in the third bin.

9. The apparatus of claim 6, wherein the channel mapper is further configured to select the subset of “

N”

audio channels, wherein the subset of “

N”

audio channels is selected such that an individual one of the “

M”

audio channels is selected at no more than two successive time frames during the plurality of successive time frames.

10. The apparatus of claim 6, wherein the selected subset of “

N”

audio channels during the first time frame includes eleven audio channels corresponding to eleven portions of the audio spectrum having a strongest signal selected from the “

M”

audio channels during the first time frame, and wherein the first time frame is in a range of approximately 4 milliseconds to 7.5 milliseconds.

11. The apparatus of claim 6, further comprising a temperature monitor placed inside the cochlea to monitor and feedback a temperature for use in limiting a stimulation rate of each corresponding pulsed light signal.

12. The apparatus of claim 6, further comprising a patient-activatable electromagnetic emergency-off mechanism.

13. The apparatus of claim 6, wherein the apparatus includes an implanted device and an externally worn device, wherein the externally worn device is configured to wirelessly communicate with the implanted device, and wherein the audio processor is contained at least in part within the externally worn device, the apparatus further comprising:

a fail-safe circuit configured to turn off the optical generator if and when communications are lost to the externally worn device.

14. The apparatus of claim 6, wherein the apparatus includes an implanted device and an externally worn device, wherein the externally worn device is configured to wirelessly communicate with the implanted device, and wherein the audio processor is contained at least in part within the externally worn device.

15. The apparatus of claim 6, wherein the apparatus includes an implanted device and an externally worn device, wherein the externally worn device is configured to wirelessly communicate with the implanted device, and wherein the audio sensor is contained within the externally worn device.

16. The apparatus of claim 6, wherein a stimulation rate of each corresponding pulsed light signal is greater than 150 pulses per second.

19. The apparatus of claim 6, wherein the optical generator includes a vertical-cavity surface emitting laser (VCSEL).

20. The apparatus of claim 6, wherein the optical generator includes a plurality of vertical-cavity surface emitting lasers (VCSELs) arranged in an array.