Multi-position sampling valve

• US 8,840,852 B2
• Filed: 12/02/2008
• Issued: 09/23/2014
• Est. Priority Date: 12/07/2007
• Status: Expired due to Fees

• Current Assignee: Horiba Abx SAS (Horiba Limited)
• Original Assignee: Horiba Abx SAS (Horiba Limited)
• Inventors: Bouchentouf, Olivier
• Primary Examiner(s): Xu, Robert
• Application Number:
  US12/746,566
• Publication Number:
  US 20110281373A1
• Time in Patent Office: 2,121 Days
• Field of Search: None
• US Class Current: 422/538
• CPC Class Codes: G01N 1/18 with provision for splitting samples into portions G01N1/12, G01N1/14 take precedence; fraction-collection apparatus for chromatography B01D15/08
• CPC Class Codes: G01N 35/1097 characterised by the valves valves in general F16K
• CPC Class Codes: Y10T 436/2575 Volumetric liquid transfer

Abstract

The invention relates to a sampling valve, for taking samples of fluid from a common collecting vessel in order to perform a plurality of analyses using reagents. The valve of the invention comprises two members that are movable relative to each other, comprising a sampling member having sampling loops, each intended to receiving an aliquot of fluid, and a connection member capable of assuming at least three functional positions relative to the sampling member. These three positions enable the delayed access to two separate sampling circuits in order to fill them and to dispense reagents to the loops that make them up.

Claims

1. A sampling valve for taking a fluid for a plurality of analyses using reagents from a single collecting vessel, said valve comprising two members in contact with each other via respective ones of their faces referred to as “

contact”

faces, the two members being movable relative to each other, each member having a network of fluid-flow channels, at least some of which open out into the contact face thereof, wherein the network of channels of one of said members, referred to as a so-called sampling member, comprises at least three independent sampling loops, each suitable for containing an aliquot of the fluid, the sampling valve having at least as many reagent-dispenser channels and aliquot-outlet channels as it has loops, the other member, referred to as a so-called connection member, being capable of taking at least three distinct functional positions relative to the sampling member;

a first position enabling a fluid inlet into the valve to be connected to a first sampling circuit comprising a plurality of sampling loops that are then connected to one another via channels of the network of channels of the connection member that are then specifically in alignment with each of the loops, said first position also serving to connect, via one or more channels of the network of channels of the connection member, at least one loop of a second sampling circuit, having at least one sampling loop, to a reagent-dispenser channel and to an aliquot-outlet channel;

a second position enabling the fluid inlet to be connected to the second sampling circuit, while, in said second position, at least one sampling loop of the first sampling circuit is isolated from each of the fluid inlet, the reagent-dispenser channels and the aliquot-outlet channels; and

a third position in which said at least one sampling loop of the first sampling circuit is connected via channels of the network of channels of the connection member to a reagent-dispenser channel and to an aliquot-outlet channel, while, in said third position, said at least one sampling loop of the second sampling circuit is isolated from each of the fluid inlet, the reagent-dispenser channels and the aliquot-outlet channels.

2. A sampling valve according to claim 1, wherein, in the third position, all of the loops of the first circuit are each connected, via channels of the network of channels of the connection member to a respective reagent-dispenser channel and to a respective aliquot-outlet channel.

3. A sampling valve according to claim 1, wherein the connection member is designed to take a third position such that a fraction only of the sampling loops of the first circuit are each connected, via channels of the network of channels of the connection member, to a respective reagent-dispenser channel and to a respective aliquot-outlet channel, and to take at least other functional position such that at least one other distinct fraction of the sampling loops of the first circuit are each connected, via channels of the network of channels of the connection member, to a respective reagent-dispenser channel and to a respective aliquot-outlet channel.

4. A sampling valve according to claim 3, wherein the second position for connecting the fluid inlet to the second sampling circuit is also another functional position such that at least one other fraction of the sampling loops of the first circuit are each connected via channels of the network of channels of the connection member to a respective reagent-dispenser channel and to a respective aliquot-outlet channel.

5. A sampling valve according to claim 3, wherein each of the sampling loop fractions is constituted by a pair of sampling loops.

6. A sampling valve according to claim 3, wherein each sampling loop fractions is constituted by a single sampling valve loop.

7. A sampling valve according to claim 1, wherein the connection member is also a dispenser member carrying the reagent-dispenser channels and the aliquot-outlet channels of the sampling valve.

8. A sampling valve according to claim 1, wherein the sampling member is also a dispenser member carrying the reagent-dispenser channels and the aliquot-outlet channels of the sampling valve.

9. A sampling valve according to claim 1, wherein the members are disks that are movable in rotation relative to each other.

10. A sampling valve according to claim 1, wherein the connection member carries a channel constituting the fluid inlet to the valve.

11. A sampling valve according to claim 1, wherein the sampling member carries a channel constituting the fluid inlet into the valve.

12. A sampling valve according to claim 1, wherein the fluid is a biological fluid and the first circuit is dedicated to routine analyses and the second circuit is dedicated to particular analyses.

13. A fluid analysis appliance implementing at least one sampling valve according to claim 1.