Polymeric topical compositions
First Claim
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1. A topical pharmaceutical composition comprising:
- (a) an antibacterial agent,(b) a polyvinylpyrrolidone-vinyl acetate (PVP/VA) co-polymer in an amount from about 30% to about 60% by weight,(c) water in an amount from about 20% to about 40% by weight, and(d) a volatile solvent in an amount from about 10% to about 25% by weight;
and optionally a gelling agent or other dermatologically acceptable excipients thereof.
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Abstract
The present invention relates to topical antibacterial compositions. The compositions comprise an antibacterial agent such as mupirocin, water, a polymer and a volatile solvent present in an amount of less than about 40%. The invention also relates to methods of treatment by administering the compositions to a patient in need thereof, and to the use of such compositions in the treatment of bacterial conditions.
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Citations
23 Claims
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1. A topical pharmaceutical composition comprising:
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(a) an antibacterial agent, (b) a polyvinylpyrrolidone-vinyl acetate (PVP/VA) co-polymer in an amount from about 30% to about 60% by weight, (c) water in an amount from about 20% to about 40% by weight, and (d) a volatile solvent in an amount from about 10% to about 25% by weight; and optionally a gelling agent or other dermatologically acceptable excipients thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A topical pharmaceutical composition comprising:
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(a) an antibacterial agent, (b) a polyvinylpyrrolidone-vinyl acetate (PVP/VA) co-polymer in an amount from about 30% to about 60% by weight, (c) water in an amount from about 20% to about 40% by weight, and (d) a volatile solvent in an amount from about 10% to about 25% by weight; (e) a co-solvent present in an amount of about 1% to about 30% by weight; and optionally a gelling agent or other dermatologically acceptable excipients thereof.
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Specification