Charged particle beam extraction method and apparatus used in conjunction with a charged particle cancer therapy system

• US 8,841,866 B2
• Filed: 05/21/2009
• Issued: 09/23/2014
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Yegorovich Balakin
• Inventors: Balakin, Vladimir Yegorovich
• Primary Examiner(s): Owens, Douglas W
• Assistant Examiner(s): LUONG, HENRY T
• Application Number:
  US12/994,126
• Publication Number:
  US 20110266455A1
• Time in Patent Office: 1,951 Days
• Field of Search: 315500-507
• US Class Current: 315/500
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: G21K 1/087 by electrical means
• CPC Class Codes: G21K 1/093 by magnetic means
• CPC Class Codes: G21K 1/14 using charge exchange devices, e.g. for neutralising or changing the sign of the electrical charges of beams producing or accelerating neutral particle beams H05H3/00
• CPC Class Codes: H05H 13/04 Synchrotrons
• CPC Class Codes: H05H 7/04 Magnet systems , e.g. undulators, wigglers free-electron laser H01S3/0903; Energisation thereof
• CPC Class Codes: H05H 7/08 Arrangements for injecting particles into orbits
• CPC Class Codes: H05H 7/10 Arrangements for ejecting particles from orbits

Abstract

The invention comprises a charged particle beam extraction method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors. The system uses a radio-frequency cavity system to induce betatron oscillation of a charged particle stream. Sufficient amplitude modulation of the charged particle stream causes the charged particle stream to hit a material, such as a foil. The foil decreases the energy of the charged particle stream, which decreases a radius of curvature of the charged particle stream in the synchrotron sufficiently to allow a physical separation of the reduced energy charged particle stream from the original charged particle stream. The physically separated charged particle stream is then removed from the system by use of an applied field and deflector.

Claims

1. An apparatus for extracting a circulating charged particle beam from a synchrotron, said synchrotron having a center, said apparatus comprising:

an extraction material;

at least a one kilovolt direct current field applied across a pair of extraction blades;

a deflector;

a patient respiration monitor generating a respiration signal; and

a main controller, wherein the circulating charged particle beam passes through said extraction material resulting in a reduced energy charged particle beam, wherein the reduced energy charged particle beam passes between said pair of extraction blades, wherein the direct current field redirects the reduced energy charged particle beam through said deflector, wherein said deflector yields an extracted charged particle beam, wherein said extraction material comprises a foil less than about one hundred fifty micrometers thick, wherein a radio frequency voltage applied across a first pair of blades is configured to induce a betatron oscillation on the circulating charged particle beam, wherein a first distance between said center of said synchrotron and said pair of extraction blades is less than a second distance between said center of said synchrotron and said pair of first blades, wherein the circulating charged particle beam comprises a radius of curvature passing through said first pair of blades, wherein the reduced energy charged particle beam, resulting from transmission through said extraction material, comprises a radius of curvature passing through said extraction blades, wherein timing of the extracted charged particle beam is synchronized to said respiration signal, and said main controller timing all of;

(1) particle beam injection, (2) particle beam acceleration, and (3) timing of said radio frequency voltage to synchronize with said respiration signal.

2. The apparatus of claim 1, wherein said extraction material consists essentially of atoms having six or fewer protons.

3. The apparatus of claim 2, wherein said deflector comprises a Lambertson magnet.

4. The apparatus of claim 1, wherein said extraction material comprises any of:

beryllium;

lithium hydride; and

carbon.

5. The apparatus of claim 1, wherein the circulating charged particle beam traverses said first pair of blades during acceleration.

6. The apparatus of claim 1, wherein an inner blade of said first pair of blades is in common with an outer blade of said pair of extraction blades.

7. The apparatus of claim 1, further comprising an intensity controller controlling intensity of the extracted charged particle beam via a feedback control.

8. The apparatus of claim 7, wherein an induced current results from the circulating charged particle beam passing through said extraction material, wherein the induced current comprises a feedback input to said intensity controller.

9. The apparatus of claim 1, wherein the extracted charged particle beam is synchronized in time to patient respiration using said respiration signal.

10. The apparatus of claim 1, further comprising an intensity controller controlling intensity of the extracted charged particle beam via a feedback control.

11. The apparatus of claim 10, wherein an induced current results from the circulating charged particle beam passing through said extraction material, wherein the induced current comprises a feedback input to said intensity controller.

12. The apparatus of claim 10, wherein said intensity controller alters an applied radio frequency inducing betatron oscillation on the circulating charged particle beam.

13. The apparatus of claim 1, further comprising at least one turning magnet.

14. The apparatus of claim 13, wherein said turning magnet comprises a magnetic field concentrating first magnet, wherein said first magnet comprises:

a gap through which the circulating charged particle beam circulates;

a first cross-section diameter not in contact with said gap; and

a second cross-sectional diameter proximate said gap, wherein said second cross-section diameter is less than seventy percent of said first cross-sectional diameter, wherein a magnetic field passing through said first cross-sectional diameter concentrates in said second cross-sectional diameter before crossing said gap.

15. An apparatus for extracting a circulating charged particle beam from a synchrotron, said synchrotron having a center, said apparatus comprising:

an extraction material;

at least a one kilovolt direct current field applied across a pair of extraction blades;

a deflector,

wherein the circulating charged particle beam passes through said extraction material resulting in a reduced energy charged particle beam,

wherein the reduced energy charged particle beam passes between said pair of extraction blades,

wherein the direct current field redirects the reduced energy charged particle beam through said deflector,

wherein said deflector yields an extracted charged particle beam,

wherein said extraction material comprises any of;

beryllium;

lithium hydride; and

carbon, and

wherein said extraction material comprises a foil of about thirty to one hundred micrometers thickness.

16. The apparatus of claim 15, further comprising a main controller, said main controller timing all of:

(1) particle beam injection,

(2) particle beam acceleration, and

(3) timing of said radio frequency voltage to synchronize with said respiration signal.

17. A method for extracting a circulating charged particle beam from a synchrotron, comprising the steps of:

transmitting the circulating charged particle beam through an extraction material, said extraction material yielding a reduced energy charged particle beam,

wherein said extraction material comprises any of;

beryllium;

lithium hydride; and

carbon, and

wherein said extraction material comprises a foil of about forty to sixty microns thickness;

applying at least five hundred volts across a first pair of blades; and

passing the reduced energy charged particle beam between said first pair of blades,

wherein said first pair of blades redirect the reduced energy charged particle beam to a deflector, and

wherein said deflector yields an extracted charged particle beam.

18. The method of claim 17, wherein said extraction material consists essentially of atoms having six or fewer protons.

19. The method of claim 17, further comprising the step of:

inducing betatron oscillation using a second pair of blades, wherein the circulating charged particle beam passes between said second pair of blades prior to said step of transmitting.

20. The method of claim 17, further comprising the step of:

applying a radio frequency voltage across a second pair of blades to alter the circulating path of the circulating charged particle beam.

21. The method of claim 17, wherein a first distance between said center of said synchrotron and said first pair of blades is less than a second distance between said center of said synchrotron and said second pair of blades,

wherein the circulating charged particle beam comprises a second radius of curvature passing through said second pair of blades,

wherein the reduced energy charged particle beam, resulting from transmission through said extraction material, comprises a first radius of curvature passing through said first pair of blades

wherein said reduced energy charged particle beam exits said synchrotron within an inner diameter of said circulating charged particle beam.

22. The method of claim 21, further comprising the step of:

controlling intensity of the extracted charged particle beam with an intensity controller using a feedback control.

23. The method of claim 22, wherein an induced current results from the circulating charged particle beam passing through said extraction material, wherein the induced current comprises a feedback input to said step of controlling intensity.

24. The method of claim 17, further comprising the step of:

controlling intensity of the extracted charged particle beam with an intensity controller using a feedback control.

25. The method of claim 24, wherein an induced current results from the circulating charged particle beam passing through said extraction material, wherein the induced current comprises a feedback input to said step of controlling intensity.

26. The method of claim 25, wherein said intensity controller alters duration of an applied radio frequency inducing altered trajectory of the circulating charged particle beam.

27. A method for extracting a circulating charged particle beam from a synchrotron, comprising the steps of:

providing a turning magnet in said synchrotron, said turning magnet wound by a winding coil and a correction coil;

providing a first current to said winding coil and a second current to said correction coil, said second current less than ten percent of said first current;

generating a feedback signal using a magnetic field sensor, said magnetic field sensor proximate said turning magnet;

stabilizing a magnetic field about said turning magnet using said feedback signal in control of said second current applied to said correction coil;

after said step of stabilizing the magnetic field, transmitting the circulating charged particle beam through an extraction material, said extraction material yielding a reduced energy charged particle beam;

applying a field of at least five hundred volts across a pair of extraction blades;

passing the reduced energy charged particle beam between said pair of extraction blades,

wherein said field redirects the reduced energy charged particle as an extracted charged particle beam.

28. The method of claim 27, further comprising the step of:

synchronizing said step of transmitting with a patient respiration signal.

29. The method of claim 27, further comprising the step of:

prior to said step of transmitting, inducing betatron oscillation on the circulating charged particle beam,

wherein said step of inducing occurs at a selected energy level of the circulating charged particle beam,

wherein the betatron oscillation increases average radius of curvature of the circulating charged particle beam until said step of transmitting yields the reduced energy charged particle beam,

wherein said step of inducing at said selected energy level yields an energy controlled extracted charged particle beam.

30. The method of claim 29, further comprising the step of:

controlling intensity of the energy controlled extracted charged beam with an intensity controller.

31. The method of claim 30, wherein said step of controlling comprises the steps of:

inputting a feedback signal to said intensity controller, said step of transmitting yielding emitted electrons in the process of the circulating charged particle beam striking said extraction material, wherein the emitted electrons are converted to said feedback signal;

comparing said feedback signal to an irradiation plan intensity;

adjusting betatron oscillation with said intensity controller until said feedback signal proximately equals said irradiation plan intensity,

wherein said energy controlled extracted charged particle beam comprises an independent intensity control.

32. The method of claim 27, further comprising the steps of:

inducing a change in radial movement of the circulating charged particle beam;

(1) after acceleration of the charged particle beam to a selected energy and (2) prior to said step of transmitting the circulating charged particle beam through said extraction material; and

controlling intensity of said extracted charged particle beam using an electron flow resultant from the charged particle beam transmitting through said extraction material.

33. The method of claim 32, wherein energy control of said extracted charged particle beam is independent of intensity control of said extracted charged particle beam.