Tissue penetration device
First Claim
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1. A method of injecting an agent into the tissue of a patient at a known predetermined depth, comprising:
- (a) driving an elongate injection shaft having a tissue penetrating outlet port configured to dispense an agent at a controllable time toward the patient'"'"'s target tissue;
(b) using a velocity control system in communication with a controllable driver to control a velocity of the elongate injection shaft while advancing the elongate injection shaft into the target tissue at a first velocity from the contact point over a displacement equal to the sum of an elastic recoil displacement value for the target tissue, the distance between a distal extremity of the elongate injection shaft and the outlet port, and the desired tissue depth of injection for agent deposition;
(c) injecting the agent; and
(d) accurately delivering the agent to a specific depth within a skin or tissue layer and provide for localized agent delivery, retracting the elongate injection shaft at a second velocity that is different that the first velocity.
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Abstract
An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft.
2991 Citations
6 Claims
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1. A method of injecting an agent into the tissue of a patient at a known predetermined depth, comprising:
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(a) driving an elongate injection shaft having a tissue penetrating outlet port configured to dispense an agent at a controllable time toward the patient'"'"'s target tissue; (b) using a velocity control system in communication with a controllable driver to control a velocity of the elongate injection shaft while advancing the elongate injection shaft into the target tissue at a first velocity from the contact point over a displacement equal to the sum of an elastic recoil displacement value for the target tissue, the distance between a distal extremity of the elongate injection shaft and the outlet port, and the desired tissue depth of injection for agent deposition; (c) injecting the agent; and (d) accurately delivering the agent to a specific depth within a skin or tissue layer and provide for localized agent delivery, retracting the elongate injection shaft at a second velocity that is different that the first velocity. - View Dependent Claims (2, 3, 4, 5)
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6. A method of injecting an agent into the tissue of a patient at a known predetermined depth, comprising:
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(a) driving an elongate injection shaft having a tissue penetrating outlet port configured to dispense an agent at a controllable time toward the patient'"'"'s target tissue; (b) determining a contact point between a distal extremity of the elongate injection shaft and the target tissue; (c) advancing the elongate injection shaft into the target tissue from the contact point over a displacement equal to the sum of an elastic recoil displacement value for the target tissue, the distance between a distal extremity of the elongate injection shaft and the tissue penetrating outlet port, and the desired tissue depth of injection for agent deposition; (d) injecting the agent;
(e) and wherein using a position feedback loop of a controllable driver coupled to the elongate injection shaft.
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Specification