Sealable attachment of endovascular stent to graft

• US 8,845,714 B2
• Filed: 06/14/2011
• Issued: 09/30/2014
• Est. Priority Date: 05/15/2003
• Status: Expired due to Fees

• Current Assignee: Lifeshield Sciences LLC (Acacia Research Corporation)
• Original Assignee: Lifeshield Sciences LLC (Acacia Research Corporation)
• Inventors: DiMatteo, Kristian, Spiridigliozzi, John, Thistle, Robert C.
• Primary Examiner(s): MCEVOY, THOMAS M
• Application Number:
  US13/160,105
• Publication Number:
  US 20110245906A1
• Time in Patent Office: 1,204 Days
• Field of Search: 623/1.15, 623 123- 125, 623/1.27, 623/1.35, 623/2.11, 623/1.26, 623/2.17, 623/1.36, 623/1.16
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable

Abstract

An endovascular prosthesis of the present invention includes an expandable stent and a means for sealably attaching a tubular graft to the stent within the stent'"'"'s lumen. The means of sealably attaching a graft includes membranes, foams, polymeric materials and combinations thereof. Additionally, the present invention includes methods of forming an endovascular prosthesis and methods of implanting an endovascular prosthesis within a vessel to provide sealable securement of a tubular graft within the stent'"'"'s lumen.

Claims

1. An endovascular prosthesis comprising:

a first stent, the first stent comprising a first end, a second end, and an inner surface defining an inner lumen;

a first graft, the first graft comprising a first end, a second end, and an outer surface;

a first membrane, the first membrane being non-planar with a first end having a first width sufficient to extend across an entirety of the inner lumen of the first stent;

a second end having a second width less than the first width where only the first end is engaged to the inner surface of the stent, the second end comprising a first peak formation comprising an apex, the apex comprising a first graft receiving member configured to receive a graft, wherein the first membrane is non-planar with and without a graft positioned within the first graft receiving member, the first membrane being engaged between the first and second ends of the first stent;

the first graft being positioned within the first graft receiving member, a first portion of the first peak formation conforming to a portion of the outer surface of the first graft, the apex of the first peak formation being closer to the first end of the first graft than the first portion of the first peak formation is to the first end of the first graft;

wherein the first end of the first stent, the first end of the first graft, and the apex of the first peak formation are directed in a first direction;

the second end of the first stent and the second end of the first graft are directed in a second direction opposite the first direction, the first end of the first graft being closer to the apex of the first peak formation than the second end of the first graft.

2. The endovascular prosthesis of claim 1, the first stent having a longitudinal length greater than a longitudinal length of the first membrane.

3. The endovascular prosthesis of claim 1, the first graft having a longitudinal length greater than a longitudinal length of the first stent, wherein the second end of the first graft is a distance away from the first stent.

4. The endovascular prosthesis of claim 1, the first stent further comprising a graft engaged to an outer surface of the first stent.

5. The endovascular prosthesis of claim 1, the first peak formation further comprising a second portion, the second portion longitudinally adjacent to the first portion, the second portion being at an angle to the outer surface of the first graft, the first portion forming a majority of a longitudinal length of the first membrane.

6. The endovascular prosthesis of claim 1, the first stent being a tubular stent with a single opening at the distal end and a single opening at the proximal end.

7. The endovascular prosthesis of claim 1, the endovascular prosthesis further comprising a second graft, the second graft comprising a first end and having a second longitudinal length greater than a first longitudinal length of the stent;

the first membrane further comprising a second peak formation, the second peak formation comprising a first portion and an apex, the apex comprising a second graft receiving member;

the second graft being positioned within the second graft receiving member, the first portion of the second peak formation conforming to a portion of the second graft, the apex being closer to the first end of the second graft than the first portion of the first peak formation.

8. The endovascular prosthesis of claim 7, the first membrane further comprising a fluid flow opening.

9. The endovascular prosthesis of claim 8, the fluid flow opening being positioned between the first graft receiving member and the second graft receiving member.

10. The endovascular prosthesis of claim 8, the fluid flow opening being a slit, a hole, or a fluid penetrable material.

11. The endovascular prosthesis of claim 7, the first graft comprising a porous portion positioned a first distance away from the first stent, and the second graft comprising a porous portion positioned a second distance away from the first stent.

12. An endovascular prosthesis comprising:

a first stent the first stent comprising a first end a second end and an inner surface defining an inner lumen;

a first graft, the first graft comprising a first end, a second end, and outer surface;

a first membrane, the first membrane being non-planar with a first end having a first width sufficient to extend across an entirety of the inner lumen of the first stent;

a second end having a second width less than the first width where only the first end is engaged to the inner surface of the stent, the second end comprising a first peak formation comprising an apex, the apex comprising a first graft receiving member configured to receive a graft, wherein the first membrane is non-planar with and without a graft positioned within the first graft receiving member;

the first graft being positioned within the first graft receiving member, a first portion of the first peak formation conforming to a portion of the outer surface of the first graft, the apex of the first peak formation being closer to the first end of the first graft than the first portion of the first peak formation is to the first end of the first graft;

the first graft further comprising a trunk, a first leg, and a second leg, the trunk forming the first end of the first graft, the first leg extending from the trunk and terminating in a second end, the second leg extending from the trunk and terminating in a third end, at least a portion of the trunk being positioned within the first graft receiving member and the first portion of the first peak formation conforming to a portion of the trunk.

13. An endovascular prosthesis comprising:

a stent comprising a distal end, a proximal end, a longitudinal length between the distal and proximal ends, an inner lumen; and

a membrane supported by said stent, the membrane traversing the entire inner lumen, the membrane having a thickness less than the longitudinal length of the stent, the membrane being a non-planar disk with a first end wider than a second end, the membrane comprising;

a first peak formation and a first graft receiving member for sealably receiving a first tubular graft, the first peak formation having an apex, forming a part of the second end of the membrane first graft receiving member being positioned at the apex of the first peak formation, wherein at least a portion of the first peak formation is configured to conform to a portion of a first tubular graft in a sealable manner and the first graft receiving member is configured to be closer to an end of the first tubular graft than the first peak formation is to the end of the first tubular graft;

wherein the membrane is non-planar disk with and without a tubular graft positioned within the first graft receiving member;

a first tubular graft, the first graft sealably engaged to the first membrane at the first peak formation, the first tubular graft comprising a proximal end and a distal end, the proximal end of the first tubular graft being closer to the apex of the first peak formation and to the proximal end of the stent than the distal end of the first tubular graft;

wherein the proximal ends of the stent and the first tubular graft are directed in a proximal direction;

the distal ends of the stent and the first tubular graft and directed in a distal direction; and

the apex of the first peak formation is directed in the proximal direction.

14. The endovascular prosthesis of claim 13, the membrane further comprising:

a second peak formation and a second graft receiving member for sealably receiving a second tubular graft, the second peak formation having an apex, the second graft receiving member being positioned at the apex of the second peak formation, wherein at least a portion of the second peak formation is configured to conform to a portion of a second tubular graft in a sealable manner and the second graft receiving member is configured to be closer to an end of the second tubular graft than the second peak formation.

15. The endovascular graft of claim 14, further comprising:

a second graft, the second graft sealably engaged to the first membrane at the second peak formation.