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Apparatus for and method of processing biological samples

  • US 8,845,984 B2
  • Filed: 09/13/2012
  • Issued: 09/30/2014
  • Est. Priority Date: 08/27/2008
  • Status: Active Grant
First Claim
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1. A bioprocessing cartridge comprising:

  • a) at least one bioprocessing chamber configured to contain a solid support;

    b) a plurality of mesoscale and/or microscale process fluid channels in fluid communication with the bioprocessing chamber through at least one pump, wherein the at least one pump is included in or on the bioprocessing cartridge;

    c) a film or foil layer enclosing the at least one bioprocessing chamber, the plurality of mesoscale and/or microscale fluid channels, and the at least one pump; and

    d) a cartridge alignment guide configured to hold the bioprocessing cartridge in a cartridge holder of a bioprocessing device,wherein said cartridge comprises at least one access valve within a flow path defined by at least one of the plurality of process fluid channels, wherein each of said at least one access valves is located within a flow path between a process fluid connector and the at least one of the plurality of process fluid channels, each process fluid connector configured to fluidly connect the cartridge to one or more fluid containers and wherein said cartridge comprises more than one access valve, wherein each access valve is placed within a flow path between an independent process fluid connector and one of the plurality of process fluid channels, each independent process fluid connector configured to fluidly connect the cartridge to one or more fluid containers.

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