Method for magnetic resonance imaging using stimulus induced rotary saturation with a contrast agent
First Claim
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1. A method for producing an image of a subject with a magnetic resonance imaging (MRI) system, the steps comprising:
- a) administering a contrast agent to the subject;
b) applying with the MRI system, a spin-lock radiofrequency (RF) field that establishes a spin-lock condition in transverse magnetization such that the transverse magnetization in the spin-lock condition is saturated by magnetic fields generated by oscillatory motion of the contrast agent, wherein the magnetic fields generated by the oscillatory motion of the contrast agent oscillate at a frequency of the oscillatory motion;
c) acquiring with the MRI system, image data from magnetic resonance signals that are indicative of the transverse magnetization in the spin-lock condition as it is saturated by the magnetic fields generated by the oscillatory motion of the contrast agent; and
d) reconstructing, from the acquired image data, an image indicative of the contrast agent.
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Abstract
A method and system for producing an image of a subject with a magnetic resonance imaging (MRI) system, in which the presence of a contrast agent is detected using a spin-lock pulse sequence, is described. More specifically, a contrast agent that induces saturation of magnetic resonance signals responsive to a spin-lock condition is administered to a subject. A spin-lock condition is subsequently established to saturate spins in proximity to the contrast agent. Image data is then acquired with an imaging pulse sequence and images indicative of the presence of the contrast agent are reconstructed.
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Citations
14 Claims
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1. A method for producing an image of a subject with a magnetic resonance imaging (MRI) system, the steps comprising:
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a) administering a contrast agent to the subject; b) applying with the MRI system, a spin-lock radiofrequency (RF) field that establishes a spin-lock condition in transverse magnetization such that the transverse magnetization in the spin-lock condition is saturated by magnetic fields generated by oscillatory motion of the contrast agent, wherein the magnetic fields generated by the oscillatory motion of the contrast agent oscillate at a frequency of the oscillatory motion; c) acquiring with the MRI system, image data from magnetic resonance signals that are indicative of the transverse magnetization in the spin-lock condition as it is saturated by the magnetic fields generated by the oscillatory motion of the contrast agent; and d) reconstructing, from the acquired image data, an image indicative of the contrast agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification