Visualization of electrophysiology data

• US 8,849,389 B2
• Filed: 07/01/2013
• Issued: 09/30/2014
• Est. Priority Date: 11/10/2008
• Status: Active Grant

• Current Assignee: CardioInsight Technologies Inc. (Medtronic Plc)
• Original Assignee: CardioInsight Technologies Inc. (Medtronic Plc)
• Inventors: Ramanathan, Charulatha, Wodlinger, Harold M., Gasparakis, Harris, Arless, Steven G., Anderson, John E., Bhojwani, Soniya
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): CAREY, MICHAEL JAMES
• Application Number:
  US13/932,523
• Publication Number:
  US 20140005563A1
• Time in Patent Office: 456 Days
• Field of Search: 600/508, 600/509, 600/523
• US Class Current: 600/523
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/339 Displays specially adapted therefor
• CPC Class Codes: A61B 5/726 using Wavelet transforms
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick

Abstract

A method for visualization of electrophysiology information can include storing electroanatomic data in memory, the electroanatomic data representing electrical activity on an anatomic region within a patient'"'"'s body over a time period. An interval within the time period is selected in response to a user selection. A visual representation of physiological information for the user selected interval can be generated by applying at least one analysis method to the electroanatomic data. The visual representation can spatially represented on a graphical representation of the anatomic region within the patient'"'"'s body.

Claims

1. A computer implemented method, comprising:

storing electroanatomic data in memory, the electroanatomic data representing electrical activity for an anatomic region within a patient'"'"'s body;

selecting a time interval for the electrical activity in response to a user selection, wherein the user selection specifies the interval based on interacting with a representation of a waveform of electrical activity for a given location of a plurality of locations for the anatomic region; and

responsive to the user selection of the time interval, automatically generating a visual representation of physiological information for the user selected time interval by applying at least one analysis method to the electroanatomic data for each of the plurality of locations of the anatomic region within the user selected interval, the visual representation of physiological information for the user selected time interval being spatially represented on a graphical representation of at least a portion of the anatomic region.

2. The method of claim 1, further comprising:

receiving a user input that modifies the user selected interval;

re-applying the at least one method to the electroanatomic data for each of the plurality of locations of the anatomic region to compute the at least one analysis method for each of a plurality of points across the anatomic region according to the modified user selected interval; and

dynamically modifying the visual representation based on the re-application of the at least one analysis method to the electroanatomic data for each of the plurality of locations of the anatomic region within the modified user selected interval.

3. The method of claim 2, wherein a plurality of activation times are computed for each of the plurality of points, the method further comprising:

determining a cycle length between sequential activation times for each of the plurality of points; and

generating the visual representation as spatial map indicative of at least one of cycle length and a number activation times for each of the plurality of points.

4. The method of claim 2, further comprising setting a user-defined cycle length in response to a user input;

and

generating the visual representation as a map superimposed on the predetermined region based on an auto-correlation of the user-defined cycle length and the activation times computed for each the plurality of points.

5. The method of claim 1, wherein the at least one analysis method is programmed to analyze frequency for a plurality of points on the predetermined anatomic region within the patient'"'"'s body by computing a frequency spectrum for each the plurality of points according to the user selected interval.

6. The method of claim 1, further comprising:

determining a dominant frequency in the frequency spectrum for each the plurality of points; and

generating the visualization to include a dominant frequency map on the graphical representation of the anatomic region.

7. The method of claim 1, further comprising selecting the at least one analysis method from a plurality of preprogrammed analysis methods in response to a user selection input, the plurality of preprogrammed methods comprising instructions programmed to determine at least two of activation time, frequency spectrum information, dominant frequency, voltage potential, and electrogram fractionation.

10. The method of claim 1, wherein the user selected interval defines a start time and an end time that span the time interval, the method further comprising dynamically modifying the visual representation in an animated manner to represent temporal changes in the physiological information within the time interval spatially depicted by the graphical representation of the anatomic region within the patient'"'"'s body.

11. The method of claim 10, further comprising generating an indication of a current time in the interval corresponding to the dynamically modified the visual representation.

12. The method of claim 11, wherein the interval is selected from an interactive graphical representation of temporal electrophysiology information for at least one point on the anatomic region within the patient'"'"'s body, the method further comprising repeatedly traversing the interval between the start time and the stop time and dynamically modifying the visual representation based on data associated with a current time during each traversal of the interval.

13. The method of claim 1, further comprising applying an inverse method to compute the electroanatomical data for the anatomic region within the patient'"'"'s body based on patient electrical data acquired for the patient via non-invasive body surface electrodes and geometry data.

14. The method of claim 13, wherein the geometry data comprises at least one of a generic representation of the anatomic region within the patient'"'"'s body or a patient-specific representation of the anatomic region within the patient'"'"'s body derived from imaging data for the patient.

15. The method of claim 1, further comprising:

preprocessing electrical data acquired from a patient, the preprocessing including selecting at least one sample interval for the acquired electrical data in response to a user input, the electroanatomic data being generated from the acquired electrical data for the selected at least one sample interval, and

wherein the selected interval is an analysis interval, the electroanatomic data being generated according to the electrical data acquired for the at least one sample interval, the visual representation of physiological information for the user selected interval being generated by applying the at least one analysis method to the electroanatomic data that is generated according to the at least one sample interval, such that the visual representation is variable and responsive to modifications in the analysis interval based on the user selection thereof, while the at least one sample interval remains fixed.

16. The method of claim 15, wherein the at least one sample interval comprises multiple non-temporally contiguous sample intervals, the method further comprising aggregating the acquired electrical data for each of the multiple non-temporally contiguous sample intervals to provide a spliced set of electrical data, the electroanatomic data being generated based on the spliced set of electrical data.

20. The method of claim 1, wherein the at least one method is programmed to dynamically identify one or more anatomical locations that meet user-defined criteria and to automatically generate the visual representation to include a virtual identifier at each location of the anatomic region that satisfies the user-defined criteria.

8. A computer implemented method, comprising:

storing electroanatomic data in memory, the electroanatomic data representing electrical activity for an anatomic region within a patient'"'"'s body;

,

receiving a user input that defines location data corresponding to a user-selected location for at least one virtual electrode on a graphical representation of the anatomic region within the patient'"'"'s body;

generating a corresponding waveform of electrical activity for each virtual electrode based on the location data and the electroanatomic data for the received user input;

selecting a time interval for the electrical activity in response to a user input, wherein the user input specifies the interval based on interacting with the corresponding waveform of electrical activity for the at least one virtual electrode; and

responsive to the user selection of the time interval, generating a visual representation of physiological information for the user selected time interval by applying at least one analysis method to the electroanatomic data for the anatomic region, the visual representation being spatially represented on a graphical representation of at least a portion of the anatomic region.

9. The method of claim 8, wherein the visual representation comprises a graphical representation of an electroanatomic map, the method further comprising superimposing a graphical representation of the at least one virtual electrode on the interactive graphical representation of the anatomic region within the patient'"'"'s body in response to the receiving of the user input.

17. A non-transitory computer readable medium having instructions for performing a method comprising:

preprocessing electrical data acquired from a patient, the preprocessing including selecting at least one sample interval for the acquired electrical data in response to a user input;

generating electroanatomic data for an anatomic region of interest based on the acquired electrical data for the selected at least one sample interval;

storing the electroanatomic data for an anatomic region of interest;

selecting an analysis time interval for the electrical activity in response to a user selection, wherein the user selection specifies the analysis time interval based on interacting with a representation of a waveform of electrical activity for a given location of the anatomic region;

selecting at least one analysis method in response to a user input; and

generating a visual representation of physiological information for the analysis time interval by applying the selected at least one analysis method to the electroanatomic data that is generated according to the selected at least one sample interval, such that the visual representation is variable and responsive to modifications in the analysis interval based on the user selection thereof, while the at least one sample interval remains fixed, the visual representation being spatially represented on a graphical representation of at least a portion of the anatomic region of interest.

18. The medium of claim 17, wherein the method further comprises applying an inverse method to compute the electroanatomical data for the anatomic region of interest based on the acquired electrical data for at least the selected at least one sample interval, the acquired electrical data being acquired for the patient via non-invasive body surface electrodes and geometry data, the geometry data corresponding to at least one of geometry of anatomy of the patient or mathematical model.

19. The medium of claim 17, wherein the at least one analysis method is selected from a set of preprogrammed analysis methods or is programmed in response to a user input.