Identifying heart failure patients suitable for resynchronization therapy using QRS complex width from an intracardiac electrogram
First Claim
1. A system comprising:
- a signal analyzer configured to provide an atrio-ventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval is indicative of whether a wide QRS interval is present in the QRS interval for the patient; and
a controller coupled to the signal analyzer and configured to set a paced atrioventricular delay to be substantially less than an atrio-ventricular delay of the patient when the wide QRS interval is present.
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Abstract
Methods and systems are disclosed for determining whether a patient is a responder to cardiac resynchronization therapy. The beginning and ending of the intrinsic ventricular depolarization are determined through signals measured from one or more electrodes implanted in the patient'"'"'s heart. An interval between the beginning and ending of the intrinsic ventricular depolarization is computed and is compared to a threshold. The threshold may be determined empirically. The pacing parameters of a heart stimulation device, such as a pacemaker, may then be configured, for example, by setting the paced atrio-ventricular delay based on whether the patient responds positively to cardiac resynchronization therapy.
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Citations
20 Claims
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1. A system comprising:
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a signal analyzer configured to provide an atrio-ventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval is indicative of whether a wide QRS interval is present in the QRS interval for the patient; and a controller coupled to the signal analyzer and configured to set a paced atrioventricular delay to be substantially less than an atrio-ventricular delay of the patient when the wide QRS interval is present. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A system comprising:
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a signal analyzer configured to provide an atrioventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval is indicative of whether a wide QRS interval is present in the QRS interval for the patient; and a controller coupled to the signal analyzer and configured to set a paced atrioventricular delay to one-half of an atrio-ventricular delay of the patient when the wide QRS interval is present. - View Dependent Claims (18)
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19. A system comprising:
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a signal analyzer configured to provide an atrio-ventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval is indicative of whether a wide QRS interval is present in the QRS interval for the patient; and a controller coupled to the signal analyzer and configured to set a paced atrio-ventricular delay to approximately 30 milliseconds less than an atrio-ventricular delay of the patient when the wide QRS interval is not present; and set a paced atrioventricular delay to about one-half of an atrio-ventricular delay of the patient when the wide QRS interval is present. - View Dependent Claims (20)
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Specification