Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
First Claim
1. A therapy system for treating a patient'"'"'s pain, comprising:
- a pulse generator coupled to a signal delivery element to transmit multiple electrical stimulation signals to the signal delivery element, the signal delivery element comprising a lead body including one or more electrodes; and
a machine-readable medium within the pulse generator, the machine-readable medium containing instructions that, when executed, cause the pulse generator to transmit the multiple electrical stimulation signals to multiple neurons of a target sensory neural population via the signal delivery element, wherein the multiple electrical stimulation signals have a target stimulation frequency that is in a range from 3.0 kHz to 10 kHz, and wherein the multiple electrical stimulation signals produce an asynchronous sensory neuron response.
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Abstract
Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.
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Citations
24 Claims
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1. A therapy system for treating a patient'"'"'s pain, comprising:
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a pulse generator coupled to a signal delivery element to transmit multiple electrical stimulation signals to the signal delivery element, the signal delivery element comprising a lead body including one or more electrodes; and a machine-readable medium within the pulse generator, the machine-readable medium containing instructions that, when executed, cause the pulse generator to transmit the multiple electrical stimulation signals to multiple neurons of a target sensory neural population via the signal delivery element, wherein the multiple electrical stimulation signals have a target stimulation frequency that is in a range from 3.0 kHz to 10 kHz, and wherein the multiple electrical stimulation signals produce an asynchronous sensory neuron response. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for configuring a spinal cord stimulation device for treating a patient'"'"'s pain, the method comprising:
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selecting a target stimulation frequency that is above a threshold frequency corresponding to a refractory period for neurons of a target sensory neural population, wherein the target stimulation frequency is in a range from 3.0 kHz to 10 kHz; and programming the device to deliver multiple electrical stimulation signals, wherein the multiple electrical stimulation signals together produce the target stimulation frequency and an asynchronous sensory neuron response in the target sensory neural population. - View Dependent Claims (18, 19, 20)
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21. A therapy system for delivering multiple electrical stimulation signals to a patient'"'"'s spinal cord region, the system comprising:
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an implantable lead having a plurality of electrodes, wherein the lead is positionable to deliver the multiple electrical stimulation signals to a target neural population of the patient; an implantable pulse generator coupleable to the implantable lead to transmit the multiple electrical stimulation signals to the implantable lead; and a machine-readable medium containing instructions that, when executed, cause the implantable pulse generator to transmit the multiple electrical stimulation signals to the patient'"'"'s spinal cord region via the implantable lead, wherein the multiple electrical stimulation signals have a target stimulation frequency that is in a range from 3.0 kHz to 10 kHz, and wherein the multiple electrical stimulation signals produce an asynchronous sensory neuron response. - View Dependent Claims (22, 23, 24)
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Specification