Systems and methods for deriving relative physiologic measurements

• US 8,852,099 B2
• Filed: 08/01/2012
• Issued: 10/07/2014
• Est. Priority Date: 09/17/2004
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Von Arx, Jeffrey A., Mazar, Scott T., Chavan, Abhi
• Primary Examiner(s): Alter, Alyssa M
• Application Number:
  US13/564,332
• Publication Number:
  US 20120296177A1
• Time in Patent Office: 797 Days
• Field of Search: 607/60, 600/301, 600/485, 600/49
• US Class Current: 600/301
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61N 1/37217 characterised by the communication link, e.g. acoustic or tactile
• CPC Class Codes: A61N 1/37223 Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/37252 Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data

Abstract

One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines a physiologic parameter value within a patient'"'"'s body, and communicates the physiologic parameter value outside the patient'"'"'s body, for example, to the external computing device. Further, the external computing device receives the physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the physiologic parameter value and obtains an ambient condition value outside the body. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database.

Claims

1. A system for deriving relative physiologic measurement values, comprising:

an implantable medical device (“

IMD”

) operable to determine a physiologic parameter value within a patient'"'"'s body and communicate the physiologic parameter value outside the patient'"'"'s body, the IMD including a sensor operable to obtain a measured physiologic parameter value, wherein the measured physiologic parameter value comprises a value of a parameter measured within the patient'"'"'s body, and including a transmitter adapted to communicate the physiologic parameter value outside the patient'"'"'s body, wherein the physiologic parameter value comprises the measured physiologic parameter value or an absolute physiologic parameter value, wherein the absolute physiologic parameter value is based on the measured physiologic parameter value;

an external computing device including communication circuitry configured to wirelessly receive the physiologic parameter value and an integral sensor configured to sense an ambient condition value, wherein the ambient condition value comprises a value of the parameter measured outside the patient'"'"'s body, the external computing device comprising a single device operable to both;

wirelessly receive the physiologic parameter value from the IMD; and

sense the ambient condition value;

the external computing device or a backend computing system operable to calculate a relative physiologic parameter value from the ambient condition value and the physiologic parameter value; and

the external computing device or the backend computing system operable to store the calculated relative physiologic parameter value.

2. The system of claim 1, the IMD comprising a main body, the main body including a receiver in communication with the sensor, wherein the sensor comprises a remote sensor, the remote sensor operable to obtain the measured physiologic parameter value within the patient'"'"'s body and including a transmitter adapted to communicate the physiologic parameter value to the receiver.

3. The system of claim 1, wherein the external computing device is operable to communicate the relative physiologic parameter value to the IMD, and wherein the IMD is further operable to receive the relative physiologic parameter value and store it in a memory.

4. The system of claim 1, wherein the backend computing system comprises a database accessible by one or more health care providers, and wherein the one or more health care providers can obtain the relative physiologic parameter value from the database and use the relative physiologic parameter value to provide a service to the patient selected from the group consisting of diagnosing the patient, prescribing medication to the patient, providing a therapy to the patient, or modifying one or more settings of the IMD.

5. The system of claim 1, wherein the physiologic parameter value comprises at least one of a blood pressure, a temperature, a fluid flow, a strain, an electrical property, a chemical property, and a magnetic property.

6. The system of claim 1, wherein the external computing device comprises at least one of an IMD programmer and a repeater device in communication with the backend computing system.

7. The system of claim 1, wherein the IMD and the external computing device are operable to communicate via a wireless communication connection selected from the group consisting of:

a radio frequency communication connection;

an acoustic communication connection;

an electrical field communication connection; and

an optical communication connection.

8. The system of claim 1, wherein the IMD is selected from the group consisting of a physiologic parameter sensor, a pacemaker, a defibrillator, a bi-ventricular pacer, a ventricular assist blood pump, a drug delivery pump, a drug infusion device, a neurostimulating device, an intra-ocular shunt, and an intra-cranial shunt.

9. The system of claim 1, wherein the IMD is operable to provide therapy to a patient, and wherein at least one of the IMD, the external computing device, and the backend computing system uses the relative physiologic parameter value to determine a therapy to provide to the patient.

10. The system of claim 3, wherein:

the IMD comprises a processor operable to generate patient therapy information based at least in part on the relative physiologic parameter value;

the IMD is further operable to communicate the patient therapy information to the external computing device; and

the external computing device is operable to communicate the patient therapy information to the backend computing system for access by one or more health care providers.

11. A method for deriving relative physiologic measurement values, comprising:

determining a physiologic parameter value with an implantable medical device (“

IMD”

), the IMD including an implantable sensor and a transmitter, wherein the physiologic parameter value comprises a measured physiologic parameter value or an absolute physiologic parameter value, wherein the measured physiologic parameter value comprises a value of a parameter measured within the patient'"'"'s body, and wherein the absolute physiological parameter value is based on the measured physiologic parameter value;

obtaining the measured physiologic parameter value with the implantable sensor;

communicating the physiologic parameter value to an external computing device outside the patient'"'"'s body, the external computing device comprising communication circuitry configured to wirelessly receive the physiologic parameter value and an integral sensor configured to sense an ambient condition value, wherein the ambient condition value comprises a value of the parameter measured outside of the patient'"'"'s body, the external computing device comprising a single device operable to both;

wirelessly receive the physiologic parameter value from the IMD; and

sense the ambient condition value;

sensing, via the integral sensor, the ambient condition value;

communicating the physiologic parameter value and the ambient condition value from the external computing device to a backend computing system;

calculating a relative physiologic parameter value from the ambient condition value and the physiologic parameter value and storing the relative physiologic parameter value in a memory.

12. The method of claim 11, wherein the IMD comprises a main body with a receiver in acoustic communication with a remote sensor system, the remote sensor system including a transmitter adapted to acoustically communicate the physiologic parameter value to the receiver.

13. The method of claim 11, further comprising storing the relative physiologic parameter value in a database of the backend computing system accessible by one or more health care providers.

14. The method of claim 11, wherein the physiologic parameter value comprises at least one of a blood pressure, a temperature, a fluid flow, a strain, an electrical property, a chemical property, and a magnetic property.

15. The method of claim 11, wherein the external computing device comprises at least one of an IMD programmer and a repeater device in communication with the backend computing system.

16. The method of claim 11, wherein communicating the physiologic parameter value to the external computing device comprises communicating via a wireless communication connection selected from the group consisting of a radio frequency communication connection;

an acoustic communication connection;

an electric field communication connection; and

an optical communication connection.

17. The method of claim 11, wherein the IMD is selected from the group consisting of a physiologic parameter sensor, a pacemaker, a defibrillator, a bi-ventricular pacer, a ventricular assist blood pump, a drug delivery pump, a drug infusion device, a neurostimulating device, an intra-ocular shunt, and an intra-cranial shunt.

18. The method of claim 17, further comprising:

determining a therapy to provide to the patient using the relative physiologic parameter value;

providing the therapy to the patient with the IMD; and

storing the therapy information for access by one or more health care providers using the backend computing system.

19. A system for deriving relative physiologic parameter values, comprising:

an implantable medical device (“

IMD”

) including;

a remote sensor system adapted to be implanted in a patient'"'"'s body and operable to obtain a physiologic parameter value, the remote sensor system including a transmitter, wherein the physiologic parameter value comprises a measured physiologic parameter value or an absolute physiologic parameter value, wherein the measured physiologic parameter value comprises a value of a parameter measured within the patient'"'"'s body, and wherein the absolute physiologic parameter value is based on the measured physiologic parameter value;

a main body adapted to be implanted in the patient'"'"'s body, the main body including a receiver in communication with the transmitter of the remote sensor system and operable to receive the physiologic parameter value from the remote sensor system, the main body operable to communicate the physiologic parameter value outside the patient'"'"'s body;

an external computing device comprising a single device operable to;

wirelessly receive the physiologic parameter value from the IMD;

sense an ambient condition value, wherein the ambient condition value comprises a value of the parameter measured outside the patient'"'"'s body; and

communicate the physiologic parameter value to a backend computing system; and

the backend computing system operable to;

receive the physiologic parameter value from the external computing device;

obtain the ambient condition value from the external computing device;

calculate a relative physiologic parameter value from the ambient condition value and the physiologic parameter value; and

store the calculated relative physiologic parameter value in a database accessible by one or more health care providers.

20. The system of claim 19, wherein the physiologic parameter value comprises at least one of a blood pressure, a temperature, a fluid flow, a strain, an electrical property, a chemical property, and a magnetic property.

21. The system of claim 19, wherein the external computing device comprises at least one of an IMD programmer and a repeater device in communication with the backend computing system.

22. The system of claim 19, wherein the IMD and the external computing device are operable to communicate via a wireless communication connection selected from the group consisting of:

a radio frequency communication connection;

an acoustic communication connection;

an electrical field communication connection; and

an optical communication connection.

23. The system of claim 19, wherein the IMD is selected from the group consisting of a physiologic parameter sensor, a pacemaker, a defibrillator, a bi-ventricular pacer, a ventricular assist blood pump, a drug delivery pump, a drug infusion device, a neurostimulating device, an intra-ocular shunt, and an intra-cranial shunt.