Clot retrieval device for removing occlusive clot from a blood vessel

• US 8,852,205 B2
• Filed: 01/17/2014
• Issued: 10/07/2014
• Est. Priority Date: 03/09/2011
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Gilvarry, Michael, Razavi, Mahmood K., Vale, David, Griffin, Patrick, Casey, Brendan, McNamara, Jason
• Primary Examiner(s): NGUYEN, TUAN VAN
• Application Number:
  US14/158,390
• Publication Number:
  US 20140200608A1
• Time in Patent Office: 263 Days
• Field of Search: 606/113, 606/114, 606/127, 606/200
• US Class Current: 606/114
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A clot retrieval device (9501) for removing occlusive clot from a blood vessel comprises an inner elongate body (9503) and an outer elongate body (9504) at least partially overlying the inner elongate body (9503). The device also comprises an elongate member or shaft (9502) having a proximal end which extends exterior of a patient so that a user can retrieve the stent-basket device and captured clot by retracting the shaft (9502). The outer elongate body (9504) and the inner elongate body (9503) are connected to the distal end of the shaft (9502) and are expandable relative to the shaft (9502) from a collapsed delivery configuration to an expanded deployed configuration. The outer elongate body (9504) is expandable relative to the inner elongate body (9503) to a radial extent which is greater than the radial extent of the inner body (9503) in the deployed configuration. The stent-basket construction of the device creates a reception space (9507) between the inner (9503) and outer (9504) to receive the target clot. The outer body (9504) is configured to allow as much as possible of the clot to migrate through it into the internal reception space (9507). Housing the clot in this reception space rather than pinning it to the wall of the vessel means that the clot is under less compression and can thus be retracted at a lower force. The inner elongate body (9503) and a distal capture net (9505) protect the distal vascular bed from embolization.

Claims

1. A clot retrieval device for removing a clot from a blood vessel, the device comprising:

an inner tubular body having a plurality of openings, a collapsed delivery configuration, and an expanded deployed configuration; and

an outer tubular body at least partially overlying the inner tubular body and having a plurality of closed cells, the outer tubular body further including;

a first scaffolding segment including a plurality of the closed cells,

a second scaffolding segment including a plurality of the closed cells and located distally of the first scaffolding segment, the inner tubular body extending inside both the first and second scaffolding segments,

an unscaffolded clot inlet mouth located between the first scaffolding segment and the second scaffolding segment, and

a hinge connecting the first and second scaffolding segments, the hinge including a pair of connecting elements, each connecting element connected at a proximal end to the first scaffolding segment and at a distal end to the second scaffolding segment.

2. The clot retrieval device of claim 1, wherein

the unscaffolded clot inlet mouth includes an opening larger than any one of the plurality of cells of the first and second scaffolding segments.

3. The clot retrieval device of claim 1, wherein

the second scaffolding segment includes more of the closed cells than the first scaffolding segment.

4. The clot retrieval device of claim 1, wherein the unscaffolded clot inlet mouth forms a disconnection between the first scaffolding segment and the second scaffolding segment over a circumferential arc of approximately 180 degrees.

5. The clot retrieval device of claim 1, wherein the pair of connecting elements extend parallel to a central axis of the inner tubular body.

6. The clot retrieval device of claim 1, wherein the pair of connecting elements are located on an outer circumference of the outer tubular body.

7. The clot retrieval device of claim 1, wherein the hinge forms the only connection of the outer tubular body between the first and second scaffolding segments.

8. The clot retrieval device of claim 1, wherein a longitudinal distance between the first scaffolding segment and the second scaffolding segment is the same in the expanded deployed configuration as during retrieval of the device.

9. The clot retrieval device of claim 1, wherein the unscaffolded clot inlet mouth is a first clot inlet mouth, and the hinge is a first hinge, and the device further includes:

a third scaffolding segment located distally of the second scaffolding segment,

a second unscaffolded clot inlet mouth located between the second and third scaffolding segments, and

a second hinge aligned with the first hinge and extending between the second and third scaffolding segments.

10. The clot retrieval device of claim 9, wherein

the third scaffolding segment includes a plurality of the closed cells, and

the first and second clot inlet mouths each include an opening larger than any one of the plurality of closed cells of the first, second, and third scaffolding segments.

11. A clot retrieval device for removing a clot from a blood vessel, the device comprising:

an inner tubular body having a plurality of openings, a collapsed delivery configuration, and an expanded deployed configuration; and

an outer tubular body at least partially overlying the inner tubular body and having a plurality of closed cells, the outer tubular body further including;

a first segment including a plurality of the closed cells,

a second segment located distally of the first segment and including a plurality of the closed cells,

a clot inlet mouth located between the first segment and second segment, and

a pair of opposed connecting members forming a hinge connecting the first and second segments, each connecting member connected at a proximal end to the first segment and at a distal end to the second segment.

12. The clot retrieval device of claim 11, wherein the clot inlet mouth includes an opening larger than any one of the plurality of closed cells of the first and second segments.

13. The clot retrieval device of claim 11, wherein the clot inlet mouth forms a disconnection between the first segment and the second segment over a circumferential arc of approximately 180 degrees.

14. The clot retrieval device of claim 11, wherein the pair of connecting members extend parallel to a central axis of the inner tubular body.

15. The clot retrieval device of claim 11, wherein the pair of connecting members are located on an outer circumference of the outer tubular body.

16. The clot retrieval device of claim 11, wherein the pair of connecting members form the only connection of the outer tubular body between the first and second segments.

17. The clot retrieval device of claim 11, wherein a longitudinal distance between the first segment and the second segment is the same in the expanded deployed configuration as during retrieval of the device.

18. The clot retrieval device of claim 11, wherein the clot inlet mouth is a first clot inlet mouth, and the hinge is a first hinge, and the device further includes

a third segment located distal the second segment,

a second clot inlet mouth located between the second and third segments, and a second hinge aligned with the first hinge and extending between the second and third segments.

19. A clot retrieval device for removing an occlusive clot from a blood vessel, the device comprising:

an inner tubular body having a plurality of openings, a collapsed delivery configuration, and an expanded deployed configuration;

an outer tubular body at least partially overlying the inner tubular body and having a plurality of openings closed cells, the outer tubular body further including;

a first segment including a plurality of the closed cells,

a second segment located distally of the first segment and including a plurality of the closed cells,

a clot inlet mouth located between the first segment and second segment,

a pair of connecting members forming a hinge connecting the first and second segments,

each connecting member connected at a proximal end to the first segment and at a distal end to the second segment.