Microorganisms for imaging and/or treatment of tumors
First Claim
Patent Images
1. A recombinant vaccinia virus, comprising:
- a nucleic acid that encodes a sodium-dependent transporter protein; and
a nucleic acid that encodes a therapeutic agent.
3 Assignments
0 Petitions
Accused Products
Abstract
Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in diagnostic methods, such detection and imaging of tumors. The viruses also can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.
-
Citations
36 Claims
-
1. A recombinant vaccinia virus, comprising:
-
a nucleic acid that encodes a sodium-dependent transporter protein; and a nucleic acid that encodes a therapeutic agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
-
Specification