Electronically scanned optical coherence tomography with frequency modulated signals

• US 8,854,627 B2
• Filed: 08/30/2013
• Issued: 10/07/2014
• Est. Priority Date: 07/16/2001
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Barbato, Louis J.
• Primary Examiner(s): HANSEN, JONATHAN M
• Application Number:
  US14/015,131
• Publication Number:
  US 20140024947A1
• Time in Patent Office: 403 Days
• Field of Search: 356/484
• US Class Current: 356/484
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: G01B 9/02002 using two or more frequencies
• CPC Class Codes: G01B 9/02028 Two or more reference or object arms in one interferometer
• CPC Class Codes: G01B 9/02091 Tomographic interferometers, e.g. based on optical coherence

Abstract

An improved Optical Coherence Domain Reflectometry (OCDR) system is provided. One embodiment of this OCDR system outputs a detector signal carrying image depth information on multiple modulation frequencies, where each modulation frequency corresponds to a different image depth. The image depth information from the detector signal may be resolved by tuning to the desired modulation frequency. Another system for imaging body tissue uses multiple frequency modulators such that the light beam does not travel from an optical fiber to free space.

Claims

1. A system for imaging body tissue comprising:

a beam splitter configured and arranged to receive a light beam and generate a reference light beam and a sample light beam from the light beam;

a plurality of modulators, each modulator configured and arranged to receive a portion of the reference light beam, each modulator configured and arranged to modulate the portion of the reference light beam received by that modulator at a unique modulation frequency, wherein the modulation by the plurality of modulators forms a plurality of modulated reference light beams;

a beam combiner physically separated from the beam splitter and configured and arranged to receive the sample light beam reflected from a region of body tissue to be imaged and to receive the plurality of modulated reference light beams and to generate a combined light beam from the reflected sample light beam and the plurality of modulated reference light beams;

a light detector configured and arranged to receive the combined light beam and output a detector signal based on the combined light beam;

a tuner configured and arranged to receive the detector signal and to be tunable over a range of the unique modulation frequencies of the plurality of modulated reference light beams; and

a controller configured and arranged to sequentially tune the tuner to each of the unique modulation frequencies one at a time with the tuner consequently converting the detector signal to a tuner output signal.

2. The system of claim 1, further comprising a light source configured and arranged to produce the light beam.

3. The system of claim 1, wherein the system is configured and arranged to provide a different propagation delay to each of the modulated reference light beams.

4. The system of claim 1, further comprising a first light coupler configured and arranged to receive the reference light beam and a plurality of first optical fibers configured and arranged to each receive a portion of the reference light beam from the first light coupler and to deliver that portion of the reference light beam to a corresponding one of the plurality of modulators.

5. The system of claim 4, further comprising a plurality of second optical fibers configured and arranged to each receive a different one of the modulated reference light beams from a corresponding one of the plurality of modulators.

6. The system of claim 5, wherein each of the second optical fibers is configured and arranged to provide a different propagation delay to the modulated reference light beam received by that second optical fiber.

7. The system of claim 1, further comprising a second light coupler configured and arranged to receive the sample beam and to direct the sample beam to the region of body tissue to be imaged.

8. The system of claim 1, wherein the system is configured and arranged so that an amplitude of the tuner output signal provides image brightness information and a time position of the tuner output signal provides image depth information.

9. The system of claim 1, further comprising a console configured and arranged to produce and display an image based on the tuner output signal.

10. The system of claim 9, wherein the console is an ultrasound console.

16. The system of claim 1, further comprising a band pass filter disposed between the light detector and the tuner.

17. The system of claim 1, wherein the light detector is a single photodetector.

18. The system of claim 1, further comprising a motor encoder coupled to the controller.

19. The system of claim 1, wherein the beamsplitter directs less than 50% of power of the light beam into the reference light beam.

20. The system of claim 2, wherein the light source is a single light source.

11. A method of imaging body tissue, the method comprising:

providing a source beam;

splitting the source beam into a reference beam and a sample beam using a beam splitter;

splitting the reference beam into a plurality of intermediate beams;

directing each intermediate beam to a different one of a plurality of light modulators, each light modulator modulating the intermediate beam directed to that light modulator at a different modulation frequency, each modulation frequency corresponding to a different image depth;

directing the sample beam at a sample;

combining the sample beam, after being directed to the sample, with the plurality of modulated intermediate beams to form a combined beam using a beam combiner that is physically separated from the beam splitter;

converting the combined beam into a detector signal using a light detector; and

generating a tuner output signal from the detector signal using a tuner that is tuned to each of the different modulation frequencies one at a time, wherein an amplitude of the tuner output signal provides image brightness information and a time position within the tuner output signal provides image depth information.

12. The method of claim 11, further comprising generating and displaying an image based on the tuner output signal.

13. The method of claim 11, wherein generating a tuner output signal comprises sequentially tuning the tuner to each of the plurality of the different modulation frequencies in an order of the modulation frequencies corresponding to image depth to generate the tuner output signal.

14. The method of claim 11, further comprising directing the modulated intermediate light beams along different paths to provide different propagation delays to the modulated intermediate light beams.

15. The method of claim 11, converting the tuner output signal into a digital output signal.