Detector-based arterial stimulation
First Claim
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1. Apparatus for treating a subject, the apparatus comprising:
- an external device, configured for placement outside of the subject, the external device comprising;
a detector, configured to detect a factor associated with a state of the subject; and
a control unit, couplable to the detector, and configured to automatically generate a signal; and
an implant, comprising;
an antenna, configured to be placed in an artery of the subject and to receive the signal;
an effector element, comprising at least one electrode, and being couplable to an arterial site of the subject; and
a driver unit, coupled to the antenna, and configured to drive the electrode to stimulate an electrode implantation site of the subject, by driving a current into the electrode implantation site, at least in part responsively to the signal,wherein the control unit is configured to detect a level of impedance of the antenna, and to modulate the signal at least partially in response to the level of impedance of the antenna and the detected factor.
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Abstract
Apparatus is provided, including (1) an external device, configured for placement outside of a body of a subject and to sense a factor of the subject, and to generate a signal in response to the sensed factor, and (2) an implant, which comprises a wireless receiver for receiving the signal, and at least one electrode, the implant configured to drive the electrode to apply current to an aortic and/or vagal site of the subject in response to the signal.
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Citations
31 Claims
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1. Apparatus for treating a subject, the apparatus comprising:
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an external device, configured for placement outside of the subject, the external device comprising; a detector, configured to detect a factor associated with a state of the subject; and a control unit, couplable to the detector, and configured to automatically generate a signal; and an implant, comprising; an antenna, configured to be placed in an artery of the subject and to receive the signal; an effector element, comprising at least one electrode, and being couplable to an arterial site of the subject; and a driver unit, coupled to the antenna, and configured to drive the electrode to stimulate an electrode implantation site of the subject, by driving a current into the electrode implantation site, at least in part responsively to the signal, wherein the control unit is configured to detect a level of impedance of the antenna, and to modulate the signal at least partially in response to the level of impedance of the antenna and the detected factor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 27)
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17. A method for treating a subject, the method comprising:
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extracorporeally detecting a factor associated with a state of the subject; automatically, extracorporeally generating a signal; intracorporeally receiving the signal at an antenna that is disposed within an artery of the subject; detecting a level of impedance at the antenna; modulating the signal, at least partially in response to the level of impedance of the antenna and the detected factor, and automatically stimulating an electrode implantation site of the subject, by driving a current into the electrode implantation site, at least in part responsively to the signal. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 28)
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29. A method for treating a subject, the method comprising:
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generating a radio frequency signal; receiving the radio frequency signal at an antenna that is disposed in a blood vessel of the subject; detecting a level of impedance at the antenna; electrically stimulating the subject'"'"'s blood vessel by driving a current into the blood vessel; and modulating the current least partially in response to the detected level of impedance. - View Dependent Claims (30, 31)
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Specification