Lancing device with integrated thermoelectric cooler

• US 8,858,583 B2
• Filed: 11/09/2011
• Issued: 10/14/2014
• Est. Priority Date: 11/09/2011
• Status: Active Grant

• Current Assignee: Flextronics America LLC (Flextronics International Limited)
• Original Assignee: Flextronics America LLC (Flextronics International Limited)
• Inventors: Shtram, Lior, De Angeli, Marco
• Primary Examiner(s): Nguyen, Tuan V
• Assistant Examiner(s): NGUYEN, TIN DUC
• Application Number:
  US13/292,937
• Publication Number:
  US 20130116719A1
• Time in Patent Office: 1,070 Days
• Field of Search: 606/181, 606/182, 604/22, 604/117, 604/110, 604207-211, 600/583
• US Class Current: 606/181
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150129 by cooling
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150786 Optical identification systems, e.g. bar codes, colour codes
• CPC Class Codes: A61B 5/150954 Means for the detection of operative contact with patient, e.g. by temperature sensitive sensor
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit

Abstract

A lancing device (e.g., pen) having an integrated thermoelectric (e.g., Peltier) cooler. The lancing device includes an elongated heat accumulator having a lumen along which a piston having a lancet thereon translates back and forth. A Peltier device and a cooling ring are thermally interconnected to one end of the heat accumulator and include central apertures through which the lancet can extend. The lancing device also includes an integrated battery and microcontroller for supplying and regulating power to the Peltier device. Upon a current being sent through the Peltier device, a cold side of the Peltier device and hence the cooling ring gives up thermal energy and reduces in temperature. The cooling ring can then be placed about a body tissue (e.g., skin) for a period of time (e.g., 3-5 seconds) to desensitize the body tissue, and then the lancet can be fired to puncture the body tissue.

Claims

1. A lancing device, comprising:

an outer housing comprising an outer housing wall having a first end, a second end defining a lancing opening, and a chamber extending between the first and second ends that includes a central axis, wherein the outer housing wall comprises a material that allows the outer housing wall to accumulate heat;

a Peltier device for absorbing heat from a patient'"'"'s skin and passing heat to the outer housing wall, the Peltier device comprising;

a hot side having a hot surface in thermal contact with the outer housing wall;

a cold side having a cold surface interconnected to the hot side, the cold side adapted to receive heat from the patient'"'"'s skin and pass the heat to the hot side; and

a central aperture extending through the Peltier device between the hot and cold surfaces, wherein the central aperture includes a central axis, and wherein the central axes of the chamber and the central aperture are substantially collinear;

a lancet translationally mounted within the chamber for movement between at least a cocked position and a lancing position, the lancet having a lancet tip configured for contact with the patient'"'"'s skin in the lancing position;

a cooling ring for cooling the patient'"'"'s skin, the cooling ring including a first surface in thermal contact with the cold surface, an opposed second surface configured for contact with the patient'"'"'s skin, and a central aperture extending through the cooling ring between the first and second surfaces for receipt of the lancet tip in the lancing position, wherein the central aperture of the cooling ring includes a central axis, and wherein the central axis of the chamber, the central axis of the Peltier device and the central axis of the cooling ring are substantially collinear; and

a power source mounted within the outer housing that is electrically interconnected to the Peltier device, wherein a temperature of the cold side is adapted to decrease and a temperature of the hot side is adapted to increase when the power source passes a current through the Peltier device.

2. The lancing device as recited in claim 1, wherein the outer housing wall includes a length extending between the first and second ends, and the Peltier device includes a length extending between the hot and cold sides, wherein the length of the outer housing wall is greater than the length of the Peltier device.

3. The lancing device as recited in claim 2, wherein the length of the outer housing wall is between about 70-130 mm.

4. The lancing device as recited in claim 3, wherein the length of the outer housing wall is between about 90-110 mm.

5. The lancing device as recited in claim 1, wherein at least substantially an entirety of the cold surface is in thermal contact with the first surface of the cooling ring.

6. The lancing device as recited in claim 1, wherein a diameter of the central aperture of the cooling ring is less than a diameter of the central aperture of the Peltier device.

7. The lancing device as recited in claim 1, wherein an outer diameter of the outer housing wall is at least substantially equal to an outer diameter of the Peltier device.

8. The lancing device as recited in claim 1, wherein the power source includes a battery.

9. The lancing device as recited in claim 1, wherein the outer housing wall includes one or more metals.

10. The lancing device as recited in claim 1, wherein the outer housing wall includes at least one of copper, aluminum, and combinations thereof.

11. The lancing device as recited in claim 1, wherein the cooling ring includes aluminum.

12. An apparatus, comprising:

an elongated cylindrical heat accumulator, the heat accumulator including a first end, a second end defining a lancing opening, a chamber extending between the first and second ends, a length extending between the first and second ends, and a longitudinal axis extending along the chamber through a center of the heat accumulator;

a Peltier device thermally connected to the second end of the heat accumulator, the Peltier device including a hot side having a hot surface, a cold side having a cold surface, a length extending between the hot and cold surfaces, and a central aperture extending through the Peltier device between the hot and cold surfaces, wherein a central axis of the central aperture of the Peltier device and the longitudinal axis of the chamber are substantially collinear;

a cooling ring thermally connected to the Peltier device and opposed from the heat accumulator, the cooling ring including a central aperture extending through the cooling ring, wherein a central axis of the central aperture of the cooling ring is collinear with the central axis of the central aperture of the Peltier device and the longitudinal axis of the chamber, wherein the cooling ring includes a first surface in thermal contact with the cold surface and an opposed second surface configured for contact with a patient'"'"'s skin, and wherein at least substantially an entirety of the cold surface is in thermal contact with the first surface of the cooling ring; and

a lancet translationally mounted within the heat accumulator for movement between at least a cocked position and a lancing position, the lancet having a lancet tip configured for contact with the patient'"'"'s skin when the lancet is in the lancing position.

13. The apparatus as recited in claim 12, further including a battery mounted within the heat accumulator that is electrically interconnected to the Peltier device, wherein the Peltier device is adapted to receive heat collected from the patient'"'"'s skin from the cooling ring and pass the received heat to the heat accumulator to cool the patient'"'"'s skin when the battery passes a current through the Peltier device as part of a lancing procedure on the patient'"'"'s skin.

14. The apparatus as recited in claim 12, wherein a diameter of the central aperture of the cooling ring is less than a diameter of the central aperture of the Peltier device.