Hemodialysis and peritoneal dialysis systems having electrodeionization capabilities

• US 8,858,792 B2
• Filed: 03/05/2010
• Issued: 10/14/2014
• Est. Priority Date: 03/06/2009
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc., EMD Millipore Corporation (Merck & Co., Inc.)
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc., EMD Millipore Corporation (Merck & Co., Inc.)
• Inventors: Ding, Yuanpang Samuel, Lo, Ying-Cheng, Miller, Joshua James, Rohde, Justin, Karoor, Sujatha, Dupont, Stephane
• Primary Examiner(s): Kim, John
• Application Number:
  US12/718,609
• Publication Number:
  US 20100224492A1
• Time in Patent Office: 1,684 Days
• Field of Search: 210/748.1, 210/748.11, 210/200, 210/252, 210/263, 210/294, 210/295, 210/321.6, 210/501, 210/502.1, 210/195.1, 210/195.2, 204/535, 204/630, 204/632, 204/628, 204/637, 204/540, 204/536, 204/539, 604/6.08, 604/6.09, 604/29
• US Class Current: 210/195.2
• CPC Class Codes: A61M 1/1674 using UV radiation sources for sterilising the dialysate
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2202/0014 removed from the body
• CPC Class Codes: B01D 61/243 Dialysis
• CPC Class Codes: B01D 61/44 Ion-selective electrodialysis
• CPC Class Codes: B01D 61/58 Multistep processes

Abstract

Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source and an electrodeionization unit. The carbon source and urease source can be in the form of removable cartridges.

Claims

1. A portable dialysis fluid recycling system comprising:

a carbon source;

a urease source in fluid communication with the carbon source;

an electrodeionization unit in fluid communication with the urease source;

an ammonia sensor in fluid communication with the electrodeionization unit; and

an ion exchange unit in fluid communication with the electrodeionization unit, wherein at least one of the carbon source, the urease source and the ion exchange unit is provided in a removable cartridge.

2. The portable dialysis fluid recycling system of claim 1, wherein the ammonia sensor is a conductivity sensor.

3. The portable dialysis fluid recycling system of claim 1, which includes a metering source in fluid communication with the electrodeionization unit.

14. The portable dialysis fluid recycling system of claim 1, wherein the electrodeionization unit includes a central chamber, an anion chamber having an anode, and a cation chamber having a cathode.

15. The portable dialysis fluid recycling system of claim 1, wherein the electrodeionization unit is configured such that a quantity of fluid can be recirculated around the electrodeionization unit via a flow path.

16. The portable dialysis fluid recycling system of claim 1, wherein the carbon source and the urease source are each provided in the same removable cartridge.

4. A portable hemodialysis system comprising:

a carbon source;

a urease source in fluid communication with the carbon source;

an electrodeionization unit in fluid communication with the urease source;

an ammonia sensor in fluid communication with the electrodeionization unit;

an ion exchange unit in fluid communication with the electrodeionization unit; and

a dialyzer in fluid communication with the electrodeionization unit,

wherein at least one of the carbon source, the urease source and the ion exchange unit is provided in a removable cartridge.

5. The portable hemodialysis system of claim 4, wherein the ammonia sensor is a conductivity sensor.

6. The portable hemodialysis system of claim 4, which includes a metering source in fluid communication with the dialyzer.

7. The portable hemodialysis system of claim 4, which includes a filter in fluid communication with the dialyzer.

8. The portable hemodialysis system of claim 4, which includes an ultraviolet bactericidal light in fluid communication with the dialyzer.

17. The portable hemodialysis system of claim 4, wherein the electrodeionization unit includes a central chamber, an anion chamber having an anode, and a cation chamber having a cathode.

18. The portable hemodialysis system of claim 4, wherein the electrodeionization unit is configured such that a quantity of fluid can be recirculated around the electrodeionization unit via a flow path.

19. The portable hemodialysis system of claim 4, wherein the carbon source and the urease source are each provided in the same removable cartridge.

9. A portable peritoneal dialysis system comprising:

a carbon source;

a urease source in fluid communication with the carbon source; and

an electrodeionization unit in fluid communication with the urease source;

an ammonia sensor in fluid communication with the electrodeionization unit; and

an ion exchange unit in fluid communication with the electrodeionization unit,

wherein at least one of the carbon source, the urease source and the ion exchange unit is provided in a removable cartridge.

10. The portable peritoneal dialysis system of claim 9, wherein the ammonia sensor is a conductivity sensor.

11. The portable peritoneal dialysis system of claim 9, which includes a metering source in fluid communication with the electrodeionization unit.

12. The portable peritoneal dialysis system of claim 9, which includes a filter in fluid communication with the electrodeionization unit.

13. The portable peritoneal dialysis system of claim 9, which includes an ultraviolet bactericidal light in fluid communication with the electrodeionization unit.

20. The portable peritoneal dialysis system of claim 9, wherein the electrodeionization unit includes a central chamber, an anion chamber having an anode, and a cation chamber having a cathode.

21. The portable peritoneal dialysis system of claim 9, wherein the electrodeionization unit is configured such that a quantity of fluid can be recirculated around the electrodeionization unit via a flow path.

22. The portable peritoneal dialysis system of claim 9, wherein the carbon source and the urease source are each provided in the same removable cartridge.