System and method for mechanically positioning intravascular implants

• US 8,864,790 B2
• Filed: 04/16/2007
• Issued: 10/21/2014
• Est. Priority Date: 04/17/2006
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Strauss, Brian Michael, Slee, Earl Howard, Carrillo, Ramon Torres, Vu, Khoa Dang, Patterson, William Robert, Liang, Jessica, Bein, Richard Stephen, Hewitt, Todd Jeffrey, Faught, Stacy Leon, Divino, Vince, Drysen, Darrell Christopher, Ashby, Mark Philip, Klotz, Justin Arthur, Sanson, Maria De Jesus, Brennan, Scott William, Wilbur, Lawrason Charles, Oestreich, Lester Eugene
• Primary Examiner(s): Erezo, Darwin
• Assistant Examiner(s): HOLLM, JONATHAN A
• Application Number:
  US12/297,419
• Publication Number:
  US 20100030200A1
• Time in Patent Office: 2,745 Days
• Field of Search: 606/108, 606/200, 128/831, 128/843, 623/1.11
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12154 having stretch limiting means
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/2913 cams or guiding means
• CPC Class Codes: A61B 2017/2924 Translation movement of handle without rotating movement
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2230/0006 circular

Abstract

An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Claims

1. An apparatus for therapeutic implant delivery and retrieval, comprising:

a tubular wall having a distal end and a tubular wall inner cross-sectional dimension at an internal cavity, the tubular wall distal end comprising an outer surface, an inner surface, a distal end surface, and a port extending through the distal end surface along a longitudinal axis of the tubular wall, the inner surface of the tubular wall distal end at least partially enclosing the internal cavity communicating with the port, the port having a port inner cross-sectional dimension, less than the tubular wall inner cross-sectional dimension;

a cord disposed in the internal cavity comprising a distal end disposed in the port; and

an implant disposed distal of the tubular wall distal end surface and comprising an extension extending proximally through the port and past a proximally facing surface of the port and adjacent to the cord, the extension configured to engage the cord while the cord distal end is disposed in the port and while the extension is disposed within the internal cavity, wherein the cord is configured to disengage from the extension by moving the cord distal end proximally from the port to within the internal cavity;

wherein the tubular wall inner cross-sectional dimension is greater than the port cross-sectional dimension along the length of the tubular wall.

2. The apparatus of claim 1, wherein the extension comprises an extension axis, the extension being rotatable about the extension axis relative to the tubular wall distal end surface.

3. The apparatus of claim 2, wherein the extension axis is disposed at a predetermined nonzero angle relative to a tubular wall longitudinal axis.

4. The apparatus of claim 1, wherein the extension comprises a proximal end with an engagement member disposed entirely in the internal cavity, the extension being movable within the internal cavity in the direction of a tubular wall longitudinal axis.

5. The apparatus of claim 1, wherein the tubular wall further comprises a concentric ring portion having a continuous inner radial surface surrounding the internal cavity.

6. The apparatus of claim 1, wherein the implant further comprises:

a coil comprising a proximal portion and a distal portion; and

a stretch-resistant member extending through the coil and having (i) a proximal end coupled to the extension and (ii) a distal end coupled to a distal portion of the coil.

7. The apparatus of claim 6, wherein a proximal end of the extension is free of the proximal portion of the coil.

8. The apparatus of claim 1, wherein the extension extends entirely through the port.

9. The apparatus of claim 1, wherein the port comprises an inner surface that tapers from the tubular wall inner cross-sectional dimension to the port inner cross-sectional dimension.

10. The apparatus of claim 9, wherein the inner surface defines a proximally facing chamfer.

11. The apparatus of claim 9, wherein the inner surface defines a conical shape.

12. The apparatus of claim 1, wherein the extension is configured to engage the proximally facing surface of the port while the cord distal end is disposed in the port.

13. The apparatus of claim 1, wherein the port is the only aperture of a distal region of the tubular wall that extends from the internal cavity, the distal region defining the internal cavity and the port.

14. An apparatus for therapeutic implant delivery and retrieval, comprising:

a tube having a tubular wall, a proximal end, a distal end, a distal end port, a lumen, an intermediate wall at a predetermined distance proximal to the distal end port, the intermediate wall partially extending into the lumen from the tubular wall;

a cord disposed in the lumen and extending distally beyond the intermediate wall, the cord comprising a cord distal end disposed in the port; and

an implant comprising an extension extending through the port and proximally of the distal end port and adjacent to the cord, the extension configured to engage a proximally facing surface of the port and engage the cord within the lumen while the cord distal end is disposed in the port and while the extension is disposed within the lumen;

wherein the tubular wall has a tubular wall inner cross-sectional dimension at the lumen;

wherein the port extends through the distal end along a longitudinal axis of the tubular wall, the port having a port inner cross-sectional dimension, less than the tubular wall inner cross-sectional dimension; and

wherein the tubular wall inner cross-sectional dimension is greater than the port cross-sectional dimension along the length of the tubular wall.

15. The apparatus of claim 14, wherein a portion of the cord has an enlarged portion with a distal surface disposed in the lumen.

16. The apparatus of claim 14, wherein the tube further comprises a middle portion between the proximal and distal ends, the middle portion comprising at least one section extending at least partially through the tubular wall configured to increase flexibility of the tubular wall.

17. The apparatus of claim 16, wherein the at least one section is selected from the group consisting of a skived section, a slot, a gap, a hole, a spiral cut, and a reduced thickness in the tubular wall.

18. The apparatus of claim 16, wherein the tube further comprises a longitudinal axis, the tubular wall circumscribing the longitudinal axis at the proximal end and the distal end, the tubular wall partially circumscribing the longitudinal axis at a portion of the middle portion.

19. The apparatus of claim 16, wherein the tubular wall has a first flexibility profile over a length of a proximal portion of the tubular wall, a second flexibility profile over a length of the middle portion of the tubular wall, and third flexibility profile over a length of a distal portion of the tubular wall, a flexibility of the third flexibility profile changing over the length of the distal portion.

20. The apparatus of claim 16, further comprising a radiopaque marker disposed in the at least one section.

21. The apparatus of claim 14, wherein the implant further comprises:

a coil comprising a proximal portion and a distal portion; and

a stretch-resistant member extending through the coil and having (i) a proximal end coupled to the extension and (ii) a distal end coupled to a distal portion of the coil.

22. The apparatus of claim 21, wherein a proximal end of the extension is free of the proximal portion of the coil.

23. The apparatus of claim 14, wherein the extension extends entirely through the port.

24. The apparatus of claim 14, wherein the port comprises an inner surface that tapers from the tubular wall inner cross-sectional dimension to the port inner cross-sectional dimension.

25. The apparatus of claim 24, wherein the inner surface defines a proximally facing chamfer.

26. The apparatus of claim 24, wherein the inner surface defines a conical shape.

27. The apparatus of claim 14, wherein the cord is configured to disengage from the extension by moving the cord distal end proximally from the port to within the lumen.

28. The apparatus of claim 14, wherein the port is the only aperture of a distal region of the tubular wall that extends from the lumen, the distal region defining the lumen and the port.

29. An apparatus for positioning an implant in a patient, comprising:

a delivery tube configured to be delivered into the vasculature of the patient;

a positioner tube comprising a flexible tubular wall with a longitudinal tubular wall axis and having a proximal end, a distal end and a lumen extending therethrough, the positioner tube configured to be disposed within the delivery tube, the distal end having a distal wall at least partially enclosing an internal cavity and a port in communication with the internal cavity;

an actuator engaged with the positioner tube and configured to be operated by an operator;

a cord extending through the lumen of the positioner tube, the cord having a proximal end connected to the actuator and a distal end disposed in the port and configured to be moved distally toward the port and proximally away from the port;

an implant having a proximal extension extending through the port and proximally of the port into the lumen and adjacent to the cord, wherein the proximal extension is configured to engage the cord in the lumen when the cord distal end is disposed in the port, and the proximal extension is configured to be released when the cord distal end is moved proximally out of the port;

wherein the tubular wall has a tubular wall inner cross-sectional dimension at the lumen;

wherein the port extends through the distal end along the tubular wall axis of the tubular wall, the port having a port inner cross-sectional dimension, less than the tubular wall inner cross-sectional dimension within the lumen proximal to the port;

wherein the tubular wall inner cross-sectional dimension is greater than the port cross-sectional dimension along the length of the tubular wall.

30. The apparatus of claim 29, wherein the cord distal end is configured to move distally into the port.

31. The apparatus of claim 29, wherein the port comprises an opening orthogonal to a tubular wall axis, a dimension of the opening being less than an interior diameter of the tubular wall.

32. The apparatus of claim 31, the port having an axially-orthogonal opening dimension that is less than the interior diameter of the tubular wall, the cord having an axially-orthogonal dimension less than the opening dimension of the port;

the implant proximal extension having an axially-orthogonal dimension sized and configured such that the summation of the cord dimension and the extension dimension is greater than the opening dimension.

33. The apparatus of claim 29, wherein the cord distal end is configured to move distally into abutment with a proximal surface of the distal wall and obstruct a portion of the port.

34. The apparatus of claim 29, wherein the proximal extension comprises a ball.

35. The apparatus of claim 29, wherein the implant comprises a neurological coil.

36. The apparatus of claim 29, further comprising a positioner tube sleeve positioned around the positioner tube to provide a sliding exterior surface to the positioner tube to facilitate insertion and sliding of the positioner tube into and through the delivery tube.

37. The apparatus of claim 29, wherein the implant further comprises:

a coil comprising a proximal portion and a distal portion; and

a stretch-resistant member extending through the coil and having (i) a proximal end coupled to the extension and (ii) a distal end coupled to a distal portion of the coil.

38. The apparatus of claim 37, wherein a proximal end of the extension is free of the proximal portion of the coil.

39. The apparatus of claim 29, wherein the extension extends entirely through the port.

40. The apparatus of claim 29, wherein the port comprises an inner surface that tapers from the tubular wall inner cross-sectional dimension to the port inner cross-sectional dimension.

41. The apparatus of claim 40, wherein the inner surface defines a proximally facing chamfer.

42. The apparatus of claim 40, wherein the inner surface defines a conical shape.

43. The apparatus of claim 29, wherein the proximal extension is configured to engage a proximally facing surface of the port while the cord distal end is disposed in the port.

44. The apparatus of claim 29, wherein the port is the only aperture of a distal region of the tubular wall that extends from the lumen, the distal region defining the lumen and the port.