TiN;O;Modified surface for an implantable device and a method of producing the same

• US 8,864,818 B2
• Filed: 06/24/2013
• Issued: 10/21/2014
• Est. Priority Date: 11/30/2001
• Status: Expired due to Fees

• Current Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories)
• Inventors: Malik, Shamim M., Mukherjee, Avijit
• Primary Examiner(s): SEVERSON, RYAN J
• Application Number:
  US13/924,808
• Publication Number:
  US 20130297008A1
• Time in Patent Office: 484 Days
• Field of Search: 623/1.15, 623 144- 146, 422/50, 422/63, 422/500, 424/400, 424/409, 424/417, 424/422, 424/423, 424/484, 427 224- 226, 427/2.3, 427/528, 427/530, 435/289.1, 435/293.1, 435/299.1
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/088 Other specific inorganic materials not covered by A61L31/084 or A61L31/086
• CPC Class Codes: C23C 14/0036 Reactive sputtering
• CPC Class Codes: C23C 14/0664 Carbonitrides

Abstract

Implantable devices, such as stents, having a surface modified with TiN_xO_y or TiN_xC_y are disclosed.

Claims

1. A stent comprising a TiN_xO_y compound implanted at a depth within at least a region of a surface of the stent.

2. The stent of claim 1, wherein x is 1 and y is 1 or 2.

3. The stent of claim 1, wherein the depth of the implanted TiN_xO_y compound is not greater than about 2000 Å

from the surface of the stent.

4. The stent of claim 1, additionally comprising a layer of TiN_xO_y compound deposited on at least a portion of the region of the surface of the stent where the TiN_xO_y compound is implanted.

5. The stent of claim 4, wherein, for the TiN_xO_y compound in the layer, x is 1 and y is 1 or 2.

6. The stent of claim 4, wherein the layer of TiN_xO_y compound is not more than about 48,000 Å

in thickness.

7. The stent of claim 4, wherein Ti, N, or TiN is implanted at a depth within at least a region of the surface of the stent, and at least a portion of the region of implanted TiN_xO_y being above at least a portion of the region implanted with Ti, N, or TiN.

8. The stent of claim 1, wherein the stent is made from stainless steel.

9. The stent of claim 1, wherein the surface is the tissue-contacting surface of the stent.

10. The stent of claim 1, wherein Ti, N, or TiN is implanted at a depth within at least a region of the surface of the stent, and at least a portion of the region of implanted TiN_xO_y being above at least a portion of the region implanted with Ti, N, or TiN.

11. A stent comprising a layer of TiN_xO_y and a layer of TiN disposed beneath at least a portion of the layer of TiN_xO_y.

12. The stent of claim 11, wherein a region of the layer of TiN_xO_y is implanted at a depth within a surface of the stent.

13. A method of modifying a surface of a stent, comprising implanting a TiN_xO_y compound at a depth within the surface of the stent.

14. The method of claim 13, wherein x is 1 and y is 1 or 2.

15. The method of claim 13, additionally comprising forming a layer of a TiN_xO_y compound on at least a portion of the surface of the stent where the TiN_xO_y compound is implanted.

16. The method of claim 15, wherein, for the TiN_xO_y compound in the layer, x is 1 and y is 1 or 2.

17. The method of claim 15, wherein prior to the act of implanting the TiN_xO_y compound within the surface of the stent, the method comprises implanting Ti, TiN, Or N within the surface of the stent;

wherein at least a portion of the region of implanted TiN_xO_y being above at least a portion of the region implanted with Ti, N, or TiN.

18. The method of claim 13, wherein the stent is made from stainless steel.

19. The method of claim 13, wherein prior to the act of implanting the TiN_xO_y compound within the surface of the stent, the method comprises implanting Ti, TiN, or N within the surface of the stent;

wherein at least a portion of the region of implanted TiN_xO_y being above at least a portion of the region implanted with Ti, N, or TiN.

20. A method of modifying a stent surface, comprising implanting Ti, N, or TiN into the surface of the stent and forming a layer of a TiN_xO_y compound over at least a portion of the areas where Ti, N, or TiN has been implanted.

21. A stent comprising a layer of TiN_xO_y and Ti or TiN implanted at a depth beneath at least a portion of the stent with the layer of TiN_xO_y.