Micro fluid system support and manufacturing method thereof

• US 8,865,090 B2
• Filed: 07/10/2009
• Issued: 10/21/2014
• Est. Priority Date: 02/25/2002
• Status: Expired due to Fees

• Current Assignee: Hitachi Chemical Company Limited (Resonac Holdings Corp.)
• Original Assignee: Hitachi Chemical Company Limited (Resonac Holdings Corp.)
• Inventors: Kawazoe, Hiroshi, Nakaso, Akishi, Arike, Shigeharu
• Primary Examiner(s): Bullock, In Suk
• Assistant Examiner(s): EOM, ROBERT J
• Application Number:
  US12/501,078
• Publication Number:
  US 20090274582A1
• Time in Patent Office: 1,929 Days
• Field of Search: 422/100
• US Class Current: 422/502
• CPC Class Codes: B01J 19/0093 Microreactors, e.g. miniaturised or microfabricated reactors laboratory containers with capillary fluid transport in microfabricated channels or chambers B01L3/5027
• CPC Class Codes: B01J 2219/00783 Laminate assemblies, i.e. the reactor comprising a stack of plates
• CPC Class Codes: B01J 2219/00788 Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
• CPC Class Codes: B01J 2219/00822 Metal
• CPC Class Codes: B01J 2219/00833 Plastic
• CPC Class Codes: B01J 2219/0086 Dimensions of the flow channels
• CPC Class Codes: B01J 2219/00869 Microreactors placed in parallel, on the same or on different supports
• CPC Class Codes: B01L 2200/12 Specific details about manufacturing devices
• CPC Class Codes: B01L 2300/0816 Cards, e.g. flat sample carriers usually with flow in two horizontal directions
• CPC Class Codes: B01L 2300/0838 Capillaries
• CPC Class Codes: B01L 2300/0874 Three dimensional network
• CPC Class Codes: B01L 2300/0887 Laminated structure
• CPC Class Codes: B01L 2400/0481 squeezing of channels or chambers
• CPC Class Codes: B01L 2400/0655 pinch valves
• CPC Class Codes: B01L 3/502707 characterised by the manufacture of the container or its components by shaping or joining plastic parts B29C59/00, B29C65/00; by laminating B32B37/00; manufacture of microstructural devices in general B81C
• CPC Class Codes: B81B 2201/051 Micromixers, microreactors
• CPC Class Codes: B81C 1/00119 Arrangement of basic structures like cavities or channels, e.g. suitable for microfluidic systems
• CPC Class Codes: B81C 2201/019 Bonding or gluing multiple substrate layers
• CPC Class Codes: B81C 2203/032 Gluing
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor

Abstract

A support unit for a microfluidic system includes a first support; a first adhesive layer provided on a surface of the first support; and a hollow filament laid on a surface of the first adhesive layer to have an arbitrary shape and functioning as a flow channel layer of the microfluidic system.

Claims

1. A support unit for a microfluidic system, comprising:

a first support;

a first adhesive layer provided on a surface of the first support; and

at least two hollow filaments disposed on a surface of the first adhesive layer and functioning as a flow channel layer of the microfluidic system,

a second support and,

a second adhesive layer provided on a surface of the second support, wherein the first adhesive layer and the second adhesive layer are stuck together with the at least two hollow filaments being therebetween,

wherein the at least two hollow filaments are fixed on the first support, and at least one of the at least two hollow filament intersects, contacts and crosses over at least one of the other at least two hollow filaments,

wherein fluids flowing through the at least two hollow filaments do not come into contact at the intersection of the intersecting hollow filaments,

wherein the at least two hollow filaments comprise hollow filaments that have a beginning end which is exposed and extends from the first su ort and that have an ending end which is exposed and extends from the first support, and

wherein a length of the beginning end and a length of the ending end are each shorter than a length of an unexposed portion of the at least two hollow filaments.

2. The support unit for a microfluidic system according to claim 1, wherein a metal film is formed on an outside part and surrounds an end of at least one of the at least two hollow filaments and the at least one of the at least two hollow filaments is made from a material selected from the group consisting of an organic material, glass, quartz, and carbon.

3. The support unit for a microfluidic system according to claim 2, wherein the organic material is selected from the group consisting of polyvinyl chloride resin (PVC), polyvinylidene chloride resin, polyvinyl acetate resin, polyvinyl alcohol resin (PVA), polystyrene resin (PS), acrylonitrile butadiene styrene copolymer (ABS), polyethylene resin (PE), ethylene-vinyl acetate copolymer (EVA), polypropylene resin (PP), poly-4-methylpentene (TPX), polymethyl methacrylate (PMMA), PEEK, PI, PEI, PPS, cellulose acetate, polytetrafluoroethylene resin (PTFE), tetrafluoroethylene-hexafluoropropylene resin (FEP), PFA, polyethylene-tetrafluoroethylene copolymer (ETFE), polychlorotrifluoro-ethylene (PCTFE), polyvinylidene fluoride (PVDF), polyethylene terephthalate resin (PET), polyamide resin (nylon), polyacetal (POM), polyphenylene terephthalate (PPT), polycarbonate resin (PC), polyurethane resin, polyesterelastomer, polyolefin resin, silicone resin, and polyimide resin.

4. The support unit for a microfluidic system according to claim 1, wherein at least one of the at least two hollow filaments is partially provided with an optically transparent portion.

5. The support unit for a microfluidic system according to claim 1, wherein at least one of the at least two hollow filaments have light permeability.

6. The support unit for a microfluidic system according to claim 1, wherein a laying shape of the at least two hollow filaments is fixed by the first adhesive layer.

7. The support unit for a microfluidic system according to claim 1, wherein there is a cavity within a circumference of at least one of the at least two hollow filaments.

8. The support unit for a microfluidic system according to claim 1, wherein a terminal or a circuit is formed on the surface at least one of the first support and the second support.

9. The support unit for a microfluidic system according to claim 1, wherein at least one part selected from the group consisting of a micromachine, a heat generation element, a piezoelectric element, a sensor, an electronic part, and a light part is formed on the surface of at least one of the first support and the second support.

10. The support unit for a microfluidic system according to claim 1, wherein the second adhesive layer has the same shape and has the same size as the first support.