Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye
First Claim
Patent Images
1. An article of manufacture comprising;
- a support comprising a surface;
a chemiluminescent enhancing material on the surface of the support;
an energy acceptor dye on the surface of the support;
one or more biomolecular probes on the surface of the support; and
a molecular filter on the surface of the support;
wherein the molecular filter is selected from the group consisting of hemoglobin, dabcyl, DPX and DNP C2 Amine and wherein the energy acceptor dye is a J-aggregated dye.
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Abstract
Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye such as a J-aggregated dye are described.
14 Citations
10 Claims
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1. An article of manufacture comprising;
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a support comprising a surface; a chemiluminescent enhancing material on the surface of the support; an energy acceptor dye on the surface of the support; one or more biomolecular probes on the surface of the support; and a molecular filter on the surface of the support; wherein the molecular filter is selected from the group consisting of hemoglobin, dabcyl, DPX and DNP C2 Amine and wherein the energy acceptor dye is a J-aggregated dye. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification