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Medical device with predefined activated cellular integration

  • US 8,865,857 B2
  • Filed: 06/30/2011
  • Issued: 10/21/2014
  • Est. Priority Date: 07/01/2010
  • Status: Active Grant
First Claim
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1. A medical device comprising:

  • a substrate having a surface functionalized with at least one click reactive member; and

    a chemotactic agent functionalized with at least one complementary click reactive member, wherein the at least one click reactive member and the at least one complementary click reactive member are covalently bonded, adhering the chemotactic agent directly to the surface of the substrate, and the surface of the substrate promotes cellular integration.

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