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Photoplethysmography device and method

  • US 8,868,149 B2
  • Filed: 10/16/2012
  • Issued: 10/21/2014
  • Est. Priority Date: 07/30/2009
  • Status: Active Grant
First Claim
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1. A method of measuring one or more light-absorption related blood analyte concentration parameters of a mammalian subject, the method comprising:

  • a) effecting a photoplethysmography (PPG) measurement of the subject by illuminating skin of the subject with at least two distinct wavelengths of light and determining relative absorbance at each of the wavelengths;

    b) effecting a dynamic light scattering measurement (DLS) of the subject to rheologically measure a pulse parameter of the subject;

    c) temporally correlating the results of the PPG and DLS measurements; and

    d) in accordance with the temporal correlation between the PPG and DLS measurements, assessing value(s) of the one or more light-absorption related blood analyte concentration parameter(s),wherein step (d) includes;

    i) computing a parameter descriptive of the temporal correlation between measurements of step (b) and step (c); and

    ii) in accordance with the computed temporal correlation parameter, determining a time-dependent PPG data quality value associated with each PPG measurement; and

    iii) computing the light-absorption related blood analyte concentration parameter(s) by assigning greater weight to PPG data having a higher data quality value and lesser or no weight to PPG data having a lower data quality value.

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