Neurostimulation system and method for rostro-caudally steering current using longitudinal ideal multipole configurations

• US 8,868,196 B2
• Filed: 03/14/2012
• Issued: 10/21/2014
• Est. Priority Date: 03/15/2011
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Lee, Dongchul, Zhu, Changfang
• Primary Examiner(s): DIETRICH, JOSEPH M
• Application Number:
  US13/420,140
• Publication Number:
  US 20120239110A1
• Time in Patent Office: 951 Days
• Field of Search: 607/45, 607/59
• US Class Current: 607/59
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: A61N 1/37264 Changing the program; Upgrading firmware

Abstract

A system for an electrical neurostimulator coupled to a plurality of electrodes. The system comprises a user-controlled input device configured for generating directional control signals. The system further comprises control circuitry configured for sequentially defining a plurality of different ideal bipole/tripole configurations relative to the plurality of electrodes in response to the directional control signals, generating a plurality of stimulation parameter sets respectively corresponding to the plurality of ideal bipole/tripole configurations, each stimulation parameter set defining relative amplitude values for the plurality of electrodes that emulate the respective ideal bipole/tripole configuration, and instructing the electrical neurostimulator to convey electrical energy to the plurality of electrodes in accordance with the plurality of stimulation parameter sets.

Claims

1. A system for an electrical neurostimulator coupled to a plurality of electrodes implanted within tissue of a patient, comprising:

a user-controlled input device configured for generating directional control signals; and

control circuitry configured for sequentially defining a plurality of different ideal bipole/tripole configurations relative to the plurality of electrodes in response to the directional control signals, generating a plurality of stimulation parameter sets respectively corresponding to the plurality of ideal bipole/tripole configurations, each stimulation parameter set defining relative amplitude values for the plurality of electrodes that emulate the respective ideal bipole/tripole configuration, and instructing the electrical neurostimulator to convey electrical energy to the plurality of electrodes in accordance with the plurality of stimulation parameter sets, wherein the control circuitry is configured for defining the plurality of ideal multipole configurations relative to the plurality of electrodes, such that a locus of a volume of activation (VOA) will be incrementally displaced along the tissue of the patient when the electrical neurostimulator is instructed to convey electrical energy to the plurality of electrodes in accordance with the plurality of stimulation parameter sets.

2. The system of claim 1, wherein one sequence of the different ideal bipole/tripole configurations begins with one of an ideal tripole configuration and an ideal bipole configuration and ends with the other of the ideal tripole configuration and the ideal bipole configuration.

3. The system of claim 2, wherein the one of the ideal tripole configuration and the ideal bipole configuration is an ideal tripole configuration, and the other of the ideal tripole configuration and the ideal bipole configuration is an ideal bipole configuration.

4. The system of claim 2, wherein the one of the ideal tripole configuration and the ideal bipole configuration is an ideal bipole configuration, and the other of the ideal tripole configuration and the ideal bipole configuration is an ideal tripole configuration.

5. The system of claim 2, wherein an ideal cathode at the beginning and end of the one sequence of different ideal bipole/tripole configurations has the same position relative to the plurality of electrodes.

6. The system of claim 5, wherein the control circuitry is configured for maintaining the same position of the ideal cathode relative to the plurality of electrodes throughout the one sequence of different ideal bipole/tripole configurations.

7. The system of claim 2, wherein an ideal cathode at the beginning and end of the one sequence of different ideal bipole/tripole configurations has different positions relative to the plurality of electrodes.

8. The system of claim 7, wherein the control circuitry is configured for incrementally changing the position of the ideal cathode relative to the plurality of electrodes in one direction throughout the one sequence of different ideal bipole/tripole configurations.

9. The system of claim 1, wherein one sequence of the different ideal bipole/tripole configurations begins with one of a narrow ideal bipole configuration and a wide ideal bipole configuration and ends with the other of the narrow ideal bipole configuration and the wide ideal bipole configuration.

10. The system of claim 9, wherein the one of the narrow ideal bipole configuration and the wide ideal bipole configuration is a narrow ideal bipole configuration, and the other the narrow ideal bipole configuration and the wide ideal bipole configuration is a wide ideal bipole configuration.

11. The system of claim 9, wherein the one of the narrow ideal bipole configuration and the wide ideal bipole configuration is a wide ideal bipole configuration, and the other the narrow ideal bipole configuration and the wide ideal bipole configuration is a narrow ideal bipole configuration.

12. The system of claim 9, wherein an ideal cathode at the beginning and end of the one sequence of different ideal bipole/tripole configurations has the same position relative to the plurality of electrodes.

13. The system of claim 12, wherein the control circuitry is configured for maintaining the same position of the ideal cathode relative to the plurality of electrodes throughout the one sequence of different ideal bipole/tripole configurations.

14. The system of claim 1, wherein the control circuitry is configured for sequentially defining the different ideal bipole/tripole configurations in the following order:

a narrow ideal tripole configuration, a narrow upper ideal bipole configuration, a wide upper ideal bipole configuration, a wide ideal tripole configuration, a wide lower ideal bipole configuration, a narrow lower ideal bipole configuration, and back to the narrow ideal tripole configuration.

15. The system of claim 14, wherein the control circuitry is configured for maintaining the same position of an ideal cathode relative to the plurality of electrodes between the narrow ideal tripole configuration and the wide upper ideal bipole configuration, incrementally changing the position of the ideal cathode relative to the plurality of electrodes in one direction between the wide upper ideal bipole configuration and the wide lower ideal bipole configuration, and maintaining the same position of the ideal cathode relative to the plurality of electrodes between the wide lower ideal bipole configuration and the narrow ideal tripole configuration.

16. The system of claim 14, wherein the control circuitry is configured for maintaining the same position of an ideal cathode relative to the plurality of electrodes between the wide ideal tripole configuration and the narrow lower ideal bipole configuration, incrementally changing the position of the ideal cathode relative to the plurality of electrodes in one direction between the narrow lower ideal bipole configuration and the narrow upper ideal bipole configuration, and maintaining the same position of the ideal cathode relative to the plurality of electrodes between the narrow upper ideal bipole configuration and the wide ideal tripole configuration.

17. The system of claim 1, wherein the ideal bipole/tripole configurations comprise a tripole configuration having an ideal cathode and two ideal anodes that aligned along an axis.

18. The system of claim 1, wherein the ideal bipole/tripole configurations comprise a tripole configuration having an ideal cathode and two ideal anodes that are misaligned along an axis.

19. The system of claim 1, wherein the user-control input device includes a control element, a continual actuation of which generates the directional control signals.

20. The system of claim 1, wherein the user-controlled input device comprises one or more of a graphical arrow, a joystick, a touchpad, a button pad, a group of keyboard arrow keys, a mouse, a roller ball tracking device, and horizontal and vertical rocker-type arm switches for generating the directional control signals.

21. The system of claim 1, further comprising telemetry circuitry, wherein the control circuitry is configured for transmitting the stimulation parameter sets to the neurostimulation device via the telemetry circuitry.

22. The system of claim 1, further comprising a housing containing the user input device and the control circuitry.

23. A method of providing therapy to a patient using a plurality of electrodes implanted within tissue of the patient, comprising:

generating directional control signals; and

sequentially defining a plurality of different ideal bipole/tripole configurations relative to the plurality of electrodes in response to the directional control signals;

generating a plurality of stimulation parameter sets respectively corresponding to the plurality of ideal bipole/tripole configurations; and

conveying electrical energy to the plurality of electrodes in accordance with the plurality of stimulation parameter sets, thereby emulating the respective ideal bipole/tripole configurations, and incrementally displacing a volume of activation (VOA) along the tissue of the patient.

24. The method of claim 23, wherein one sequence of the different ideal bipole/tripole configurations begins with one of an ideal tripole configuration and an ideal bipole configuration and ends with the other of the ideal tripole configuration and the ideal bipole configuration.

25. The method of claim 24, wherein the one of the ideal tripole configuration and the ideal bipole configuration is an ideal tripole configuration, and the other of the ideal tripole configuration and the ideal bipole configuration is an ideal bipole configuration.

26. The method of claim 24, wherein the one of the ideal tripole configuration and the ideal bipole configuration is an ideal bipole configuration, and the other of the ideal tripole configuration and the ideal bipole configuration is an ideal tripole configuration.

27. The method of claim 24, wherein an ideal cathode at the beginning and end of the one sequence of different ideal bipole/tripole configurations has the same position relative to the plurality of electrodes.

28. The method of claim 27, further comprising maintaining the same position of the ideal cathode relative to the plurality of electrodes throughout the one sequence of different ideal bipole/tripole configurations.

29. The method of claim 24, wherein an ideal cathode at the beginning and end of the one sequence of different ideal bipole/tripole configurations has different positions relative to the plurality of electrodes.

30. The method of claim 29, further comprising incrementally changing the position of the ideal cathode relative to the plurality of electrodes in one direction throughout the one sequence of different ideal bipole/tripole configurations.

31. The method of claim 23, wherein one sequence of the different ideal bipole/tripole configurations begins with one of a narrow ideal bipole configuration and a wide ideal bipole configuration and ends with the other of the narrow ideal bipole configuration and the wide ideal bipole configuration.

32. The method of claim 31, wherein the one of the narrow ideal bipole configuration and the wide ideal bipole configuration is a narrow ideal bipole configuration, and the other the narrow ideal bipole configuration and the wide ideal bipole configuration is a wide ideal bipole configuration.

33. The method of claim 31, wherein the one of the narrow ideal bipole configuration and the wide ideal bipole configuration is a wide ideal bipole configuration, and the other the narrow ideal bipole configuration and the wide ideal bipole configuration is a narrow ideal bipole configuration.

34. The method of claim 31, wherein an ideal cathode at the beginning and end of the one sequence of different ideal bipole/tripole configurations has the same position relative to the plurality of electrodes.

35. The method of claim 34, further comprising maintaining the same position of the ideal cathode relative to the plurality of electrodes throughout the one sequence of different ideal bipole/tripole configurations.

36. The method of claim 23, further comprising sequentially defining the different ideal bipole/tripole configurations in the following order:

a narrow ideal tripole configuration, a narrow upper ideal bipole configuration, a wide upper ideal bipole configuration, a wide ideal tripole configuration, a wide lower ideal bipole configuration, a narrow lower ideal bipole configuration, and back to the narrow ideal tripole configuration.

37. The method of claim 36, further comprising:

maintaining the same position of an ideal cathode relative to the plurality of electrodes between the narrow ideal tripole configuration and the wide upper ideal bipole configuration;

incrementally changing the position of the ideal cathode relative to the plurality of electrodes in one direction between the wide upper ideal bipole configuration and the wide lower ideal bipole configuration; and

maintaining the same position of the ideal cathode relative to the plurality of electrodes between the wide lower ideal bipole configuration and the narrow ideal tripole configuration.

38. The method of claim 36, further comprising:

maintaining the same position of an ideal cathode relative to the plurality of electrodes between the wide ideal tripole configuration and the narrow lower ideal bipole configuration;

incrementally changing the position of the ideal cathode relative to the plurality of electrodes in one direction between the narrow lower ideal bipole configuration and the narrow upper ideal bipole configuration; and

maintaining the same position of the ideal cathode relative to the plurality of electrodes between the narrow upper ideal bipole configuration and the wide ideal tripole configuration.

39. The method of claim 23, wherein the ideal bipole/tripole configurations comprise a tripole configuration having an ideal cathode and two ideal anodes that aligned along an axis.

40. The method of claim 23, wherein the ideal bipole/tripole configurations comprise a tripole configuration having an ideal cathode and two ideal anodes that are misaligned along an axis.

41. The method of claim 23, further comprising continually actuating a control element to generate the directional control signals.

42. The method of claim 23, wherein the tissue is a spinal cord, and wherein the conveyance of the electrical energy to the plurality of electrodes in accordance with the plurality of stimulation parameter sets incrementally rostro-caudally displaces the VOA along a spinal cord of the patient.