Gastro-intestinal compression device

• US 8,870,807 B2
• Filed: 07/19/2011
• Issued: 10/28/2014
• Est. Priority Date: 07/19/2010
• Status: Active Grant

• Current Assignee: Beyhan, Niyazi, Hoang Nguyen, Surag Mantri
• Original Assignee: Beyhan, Niyazi, Hoang Nguyen, Surag Mantri
• Inventors: Mantri, Surag, Nguyen, Hoang, Beyhan, Niyazi
• Primary Examiner(s): Zalukaeva, Tatyana
• Assistant Examiner(s): Hanrahan, Benedict L
• Application Number:
  US13/186,429
• Publication Number:
  US 20120065651A1
• Time in Patent Office: 1,197 Days
• Field of Search: 604 8- 9, 604/19, 604264-284, 623 2364- 2367, 623/24, 606/108, 606/151, 606153-154, 606/215
• US Class Current: 604/8
• CPC Class Codes: A61B 17/1114 of the digestive tract, e.g. bowels or oesophagus
• CPC Class Codes: A61B 2017/00818 Treatment of the gastro-intestinal system
• CPC Class Codes: A61B 2017/1132 End-to-end connections
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets
• CPC Class Codes: A61F 2002/045 Stomach, intestines
• CPC Class Codes: A61F 5/0076 preventing normal digestion, e.g. Bariatric or gastric sleeves

Abstract

Devices, methods, and systems for treating Type-2 Diabetes and/or obesity by facilitating the delivery of under-digested nutrients within the gastro-intestinal tract without substantial tissue removal are disclosed. In one aspect, the gastro-intestinal tract of a patient is modified by a gastro-intestinal treatment device comprising an elongate element configured to extend within the gastro-intestinal tract, a first attachment element and a second attachment element disposed on the elongate element, wherein the first attachment element and the second attachment element are configured to attach to the gastro-intestinal tract such that a portion of the gastro-intestinal tract is compressed between the first and the second attachment elements. The length of the gastro-intestinal tract modified by the device is effectively shortened, and its surface area is reduced.

Claims

1. A gastro-intestinal treatment device, comprising:

an elongate element configured to extend within the gastro-intestinal tract;

a first attachment element disposed on a first end of the elongate element configured to attach to the gastro-intestinal tract at a first position; and

a second attachment element disposed on the distal a second end of the elongate element configured to attach to the gastro-intestinal tract at a second position;

wherein the second attachment element is configured to cause at least a portion of the gastro-intestinal tract at the second position to be refracted towards the first position such that a region of the gastro-intestinal tract is compressed between the first and the second attachment elements and the effective length of the region of the gastro-intestinal tract is reduced;

wherein at least one of the first attachment element or the second attachment element comprises at least one self-expanding anchoring mechanism comprising a self-expanding ring with one or more protrusions, wherein the protrusions of the self-expanding ring are configured to prevent the first or the second attachment elements from migrating from the position of attachment and

wherein the device is configured to maintain the compression of the portion of the gastro-intestinal tract between the first and the second attachment elements.

2. The device of claim 1, further comprising a third attachment element disposed on the elongate element, wherein the third attachment element is configured to attach to the gastro-intestinal tract at a third position.

3. The device of claim 1, wherein the device is configured to expand a diameter of the gastro-intestinal tract.

4. The device of claim 1, wherein the device is configured to reduce a diameter of the gastro-intestinal tract.

5. The device of claim 1, further comprising a covering element, wherein at least a portion of the covering element is disposed within the elongate element.

6. The device of claim 5, wherein the covering element comprises biocompatible low friction material.

7. The device of claim 1, wherein the elongate element comprises biocompatible compliant material.

8. The device of claim 1, wherein the anchoring mechanism is a self expanding mechanism.

9. The device of claim 1, wherein the anchoring mechanism is a mechanical fastener.

10. The device of claim 1, wherein the anchoring mechanism is an inflatable balloon.

11. The device of claim 1, further comprising a tension element disposed within the elongate element.

12. The device of claim 11, wherein the tension element is a spring, a braid, or a net.

13. The device of claim 1, wherein the elongate element comprises one or more openings disposed on a surface of the elongate element.

14. The device of claim 1, wherein a degree of the compression of the gastro-intestinal tract is configured to be adjustable.

15. The device of claim 1, wherein the elongate element is configured to substantially cover the compressed portion of the gastro-intestinal tract.

16. A gastro-intestinal implantable device, comprising:

an elongate element configured to extend within a portion of a gastro-intestinal tract;

a first attachment element disposed on the elongate element configured to be implanted to the gastro-intestinal tract at a first position and a second attachment element disposed on the elongate element configured to be implanted to the gastro-intestinal tract at a second position,

wherein the second attachment element is configured to cause a portion of the gastro-intestinal tract at the second position to be retracted towards the first position such that a region of the gastro-intestinal tract is compressed between the first and the second attachment elements,

wherein at least one of the first attachment element or the second attachment element comprises at least one self-expanding anchoring mechanism comprising a self-expanding ring with one or more protrusions, wherein the protrusions of the self-expanding ring are configured to prevent the first or the second attachment elements from migrating from the position of attachment, and

wherein the device is configured to maintain the compression of the portion of the gastro-intestinal tract between the first and the second attachment elements.

17. A tissue modification device, comprising:

an elongate element configured to extend within a body region;

a first attachment element disposed on4tae proximal end a first end of the elongate element configured to attach to the body region at a first position; and

a second attachment element disposed on the distal end a second end of the elongate element configured to attach to the body region at a second position,

wherein the second attachment element at the second position is configured to be moved towards the first position to compress at least a portion of the body region between the first attachment element and the second attachment element and wherein the compression modifies the tissue structure of the body portion

wherein at least one of the first attachment element or the second attachment element comprises at least one self-expanding anchoring mechanism comprising a self-expanding ring with one or more protrusions, wherein the protrusions of the self-expanding ring are configured to prevent the first or the second attachment elements from migrating from the position of attachment, and

wherein the device is configured to maintain the compression of the portion of the gastro-intestinal tract between the first and the second attachment elements.