Portable infusion management apparatus and method

• US 8,876,756 B2
• Filed: 08/11/2011
• Issued: 11/04/2014
• Est. Priority Date: 08/11/2010
• Status: Active Grant

• Current Assignee: Fresenius KABI USA LLC (Fresenius SE & Co. KGaA)
• Original Assignee: Ivenix, Inc. (Fresenius SE & Co. KGaA)
• Inventors: Carlisle, Jeffrey A., Powers, Benjamin G.
• Primary Examiner(s): Bosques, Edelmira
• Application Number:
  US13/207,515
• Publication Number:
  US 20120041413A1
• Time in Patent Office: 1,181 Days
• Field of Search: 604/66, 604/67, 604/500
• US Class Current: 604/66
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 5/155 pressurised by gas introduced into the reservoir
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28

Abstract

A portable infusion apparatus and method are provided for controlling the delivery of medicinal fluid to a patient. A fluid delivery system receives control input to control a setting of a variable fluid flow resistor. The variable fluid flow resistor resists passage of fluid through a fluid pathway between a fluid source and a recipient. The fluid delivery system; produces a control signal indicative of the setting of the variable fluid flow resistor; derives a fluid flow rate value from the control signal; and applies pressure to the fluid source to deliver the fluid from the fluid source to the recipient through the variable fluid flow resistor at a rate as specified by the derived fluid flow rate value.

Claims

1. A method comprising:

receiving control input inputted to a fluid delivery system, the control input controlling a position setting of a variable fluid flow resistor, the variable fluid flow resistor resisting passage of fluid through a fluid pathway between a fluid source and a recipient;

producing a control signal indicative of the position setting of the variable fluid flow resistor;

deriving a fluid flow rate value from the control signal;

applying pressure to the fluid source to deliver the fluid from the fluid source to the recipient through the variable fluid flow resistor at a rate as specified by the derived fluid flow rate value; and

wherein producing the control signal includes;

physically detecting the position setting of the variable fluid flow resistor using a position sensor coupled to the variable fluid flow resistor, the position sensor physically detecting a degree to which the variable fluid flow resistor is open, the position sensor producing the control signal.

2. The method as in claim 1, wherein the control input is a single physical control action inputted by a user, the single physical control action simultaneously:

i) controlling the position setting of the variable fluid flow resistor and ii) resulting in generation of the control signal indicative of a position of the variable fluid flow resistor.

3. The method as in claim 1 further comprising:

initiating display of the derived fluid flow rate value on a display screen for viewing by a used operating the fluid delivery system, a magnitude of the derived fluid flow rate value as displayed on the display screen varying depending on the position setting of the variable fluid flow resistor.

4. The method as in claim 1 further comprising:

receiving the control input at an input apparatus physically controlled by a user, the input apparatus mechanically controlling the position setting of the variable fluid flow resistor in accordance with the control input; and

the input apparatus including the position sensor, the position sensor physically detecting the position setting of the variable fluid flow resistor and producing the control signal based on the detected position setting.

5. The method as in claim 1 further comprising:

measuring the pressure applied to the fluid source;

from the measured pressure, calculating an actual flow rate of the fluid passing from the fluid source through the variable fluid flow resistor to the recipient; and

increasing the pressure applied to the fluid source in response to detecting that the actual flow rate is less than the derived flow rate value.

6. The method as in claim 1 further comprising:

measuring the pressure applied to the fluid source to calculate an actual flow rate of the fluid passing from the fluid source through the variable fluid flow resistor to the recipient; and

decreasing the pressure applied to the fluid source in response to detecting that the actual flow rate is greater than the derived flow rate value.

7. The method as in claim 1 further comprising:

controlling an actual flow rate of the fluid delivered from the fluid source through the fluid pathway based on control of the pressure and the position setting of the variable fluid flow resistor.

8. The system as in claim 1, wherein the control signal indicates a fluid flow restriction setting of the variable fluid flow resistor, the control signal being feedback from the position sensor that monitors a position of the variable fluid flow resistor.

9. The method as in claim 1, wherein the fluid source is a first chamber in an enclosure, the first chamber containing the fluid, the enclosure including a second chamber, the method further comprising:

pumping a gas into the second chamber, the pumped gas in the second chamber exerting the pressure on the first chamber and causing the fluid in the fluid source to flow through the variable fluid flow resistor to the recipient at the derived flow rate.

10. The method as in claim 9 further comprising:

monitoring a first pressure representing a pressure of the gas pumped into the second chamber;

monitoring a second pressure representing a pressure of gas in a calibration tank, the calibration tank having a known volume;

subsequent to opening a valve disposed between the second chamber and the calibration tank, monitoring a third pressure representing pressure in a combined volume including the second chamber and the calibration tank; and

calculating a volume of air in the second chamber based on the first monitored pressure, the second monitored pressure, and the third monitored pressure.

11. The method as in claim 10 further comprising:

repeatedly calculating the volume of the air in the second chamber based on the first monitored pressure, the second monitored pressure, and the third monitored pressure; and

utilizing the repeatedly calculated volume of air in the second chamber as a basis to determine an actual flow rate of delivering the fluid from the fluid source through the variable fluid flow resistor to the recipient.

12. The method as in claim 10 further comprising:

calculating an actual flow rate of fluid through the variable fluid flow resistor based on measurements of the pressure applied to the fluid source.

13. The method as in claim 10 further comprising:

measuring a decay of the pressure in the second chamber; and

calculating a flow rate of fluid through the variable fluid flow resistor to the recipient based on an initial calculated volume in the second chamber and the measured decay of the pressure in the second chamber.

14. The method as in claim 13 further comprising:

adjusting the actual flow rate based on a measured temperature.

15. A system comprising:

an input device that receives control input, the control input physically controlling a position setting of a variable fluid flow resistor, the variable fluid flow resistor disposed in a fluid pathway between a fluid source and a recipient;

a position sensor coupled to the variable fluid flow resistor, the position sensor monitoring the variable fluid flow resistor and physically detecting a degree to which the variable fluid flow resistor is open, the position sensor producing a control signal indicative of the position setting of the variable fluid flow resistor; and

a flow controller configured to receive the control signal, the flow controller;

i) deriving a fluid flow rate setpoint from the control signal, and ii) initiating application of pressure to the fluid source to deliver the fluid from the fluid source to the recipient through the variable fluid flow resistor at the derived fluid flow rate setpoint.

16. The system as in claim 15, wherein the control input is a single control action inputted by a user, the single control action simultaneously:

i) controlling the position setting of the variable fluid flow resistor and ii) resulting in generation of the control signal representative of a position of the variable fluid flow resistor.

17. The system as in claim 15 further comprising:

a display screen, the display screen displaying the derived fluid flow rate setpoint for viewing by a user, a magnitude of the derived fluid flow rate setpoint as displayed on the display screen varying depending on the position setting of the variable fluid flow resistor.

18. The system as in claim 15, wherein the flow controller:

utilizes a measure of the pressure applied to the fluid source to calculate an actual flow rate of the fluid passing from the fluid source through the variable fluid flow resistor to the recipient; and

increases the pressure applied to the fluid source in response to detecting that the calculated actual flow rate is less than the derived fluid flow rate setpoint.

19. The system as in claim 15, wherein the flow controller:

utilizes a measure of the pressure applied to the fluid source to calculate an actual flow rate of the fluid passing from the fluid source through the variable fluid flow resistor to the recipient; and

decreases the pressure applied to the fluid source in response to detecting that the calculated actual flow rate is greater than the derived fluid flow rate setpoint.

20. The system as in claim 15, wherein the flow controller:

controls an actual flow rate of the fluid delivered from the fluid source through the fluid pathway based on controlling a magnitude of the pressure and the position setting of the variable fluid flow resistor.

21. The system as in claim 15, wherein the fluid source is a first chamber in an enclosure, the first chamber containing the fluid, the enclosure including a second chamber, the system further comprising:

a pump configured to pump a gas into the second chamber, the pumped gas in the second chamber causing exertion of the pressure on the first chamber and causing the fluid in the fluid source to flow through the variable fluid flow resistor to the recipient at the derived fluid flow rate setpoint.

22. The system as in claim 21, wherein the flow controller:

monitors a first pressure representing a pressure of the gas pumped into the second chamber;

monitors a second pressure representing a pressure of gas inputted to a calibration tank, the calibration tank having a known volume;

subsequent to opening a valve coupling the second chamber and the calibration tank, monitors a third pressure representing a pressure in a combined volume including the second chamber and the calibration tank; and

calculates a volume of air in the second chamber based on the first pressure, the second pressure, and the third pressure.

23. The system as in claim 22, wherein the flow controller:

repeatedly calculates the volume of the air in the second chamber based on the first monitored pressure, the second monitored pressure, and the third monitored pressure; and

utilizes the repeated calculated volume of air in the second chamber as a basis to determine an actual flow rate of delivering the fluid from the fluid source through the variable fluid flow resistor to the recipient.

24. The system as in claim 22, wherein the flow controller:

measures a decay of the pressure in the second chamber; and

calculates a flow rate of fluid through the variable fluid flow resistor to the recipient based on an initial calculated volume in the second chamber and the measured decay of the pressure in the second chamber.

25. The system as in claim 24, wherein the flow controller:

adjusts the calculated flow rate based on a measured temperature.