Drug delivery apparatus
First Claim
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1. A drug delivery apparatus for delivering a drug into a bodily fluid in a bodily cavity over a period of time, the apparatus comprising:
- a delivery channel, comprising an outlet, for facilitating fluid flow through a lumen thereof to and from the bodily cavity;
a drug dosing actuator for loading a drug into the delivery channel, controlled independently of a second actuator, while producing negligible flow at the outlet; and
the second actuator for driving the drug and a carrier fluid through the delivery channel, out the outlet, and into the bodily cavity.
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Abstract
An implantable drug delivery apparatus for delivering a drug into a bodily fluid in a bodily cavity of a patient over a period of time includes a drug supply reservoir to supply drug into a delivery channel and an actuator for delivering the drug to a predetermined location in the bodily cavity of the patient, such as, for example, a cochlea of a human ear. The drug is loaded into the delivery channel while producing substantially negligible flow at an outlet of the delivery channel.
170 Citations
31 Claims
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1. A drug delivery apparatus for delivering a drug into a bodily fluid in a bodily cavity over a period of time, the apparatus comprising:
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a delivery channel, comprising an outlet, for facilitating fluid flow through a lumen thereof to and from the bodily cavity; a drug dosing actuator for loading a drug into the delivery channel, controlled independently of a second actuator, while producing negligible flow at the outlet; and the second actuator for driving the drug and a carrier fluid through the delivery channel, out the outlet, and into the bodily cavity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method for delivering a drug into a bodily fluid in a bodily cavity over a period of time, the method comprising:
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loading, using a dosing pump controlled independently of a second actuator, a drug from a drug supply reservoir into a delivery channel while producing negligible flow at an outlet of the delivery channel; and activating the second actuator to drive the drug and a carrier fluid through the delivery channel, out the outlet, and into the bodily cavity. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification