Hemodialysis system with multiple cassette interference

• US 8,882,692 B2
• Filed: 08/19/2011
• Issued: 11/11/2014
• Est. Priority Date: 11/05/2003
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Lo, Ying-Cheng, Childers, Robert W., Kelly, Thomas D., Rohde, Justin
• Primary Examiner(s): SU, SUSAN SHAN
• Application Number:
  US13/213,676
• Publication Number:
  US 20110297599A1
• Time in Patent Office: 1,180 Days
• US Class Current: 604/5.01
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1563 Details of incorporated filters
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1603 Regulation parameters
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1635 with volume chamber balancing devices between used and fresh dialysis fluid
• CPC Class Codes: A61M 1/1639 linked by membranes
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/3401 Cassettes therefor
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/36224 : with sensing means or components thereof
• CPC Class Codes: A61M 1/36225 : with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 : at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362262 : Details of incorporated reservoirs
• CPC Class Codes: A61M 1/362265 : Details of valves
• CPC Class Codes: A61M 1/3627 : Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 2205/127 : with provisions for heating or cooling
• CPC Class Codes: A61M 2205/3331 : Pressure; Flow
• CPC Class Codes: A61M 2205/3368 : Temperature
• CPC Class Codes: A61M 2205/502 : User interfaces, e.g. screens or keyboards
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

A hemodialysis system for operation with a blood source and a dialysate source, the system including: (i) a first machine portion including a blood pump; (ii) a blood cassette operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette when the blood cassette is in fluid communication with the blood source; (iii) a dialyzer fluidly connected to the blood cassette; (iv) a second machine portion separate from the first machine portion, the second machine portion including a dialysate pump; and (v) a dialysate cassette separate from the blood cassette, the dialysate cassette operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette when the dialysate cassette is in fluid communication with the dialysate source, the dialysate cassette being fluidly connected to the dialyzer.

Claims

1. A hemodialysis system for operation with a blood source and a dialysate source, the system comprising:

a first machine portion including a blood pump;

a blood cassette operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette when the blood cassette is in fluid communication with the blood source;

a dialyzer fluidly connected to the blood cassette;

a second machine portion separate from the first machine portion, the second machine portion including a dialysate pump; and

a dialysate cassette separate from the blood cassette, the dialysate cassette operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette when the dialysate cassette is in fluid communication with the dialysate source, the dialysate cassette being fluidly connected to the dialyzer and including at least one balance chamber for controlling the flow of dialysate.

2. The hemodialysis system of claim 1, wherein the first machine portion is positioned adjacent to the second machine portion.

3. The hemodialysis system of claim 1, which includes a weight scale used to control dialysate flow.

4. The hemodialysis system of claim 1, which includes a door behind which one of the blood and dialysate cassettes is received.

5. The hemodialysis system of claim 1, wherein the second machine portion includes a to-dialyzer dialysate pump and a from-dialyzer dialysate pump, and wherein the dialysate cassette includes a to-dialyzer tube positioned and arranged to operate with the to-dialyzer dialysate pump and a from-dialyzer tube positioned and arranged to operate with the from-dialyzer dialysate pump.

6. The hemodialysis system of claim 5, wherein the to- and from- dialyzer tubes are peristaltic tubing segments and the to- and from-dialyzer dialysate pumps are peristaltic pumps.

7. The hemodialysis system of claim 5, wherein the to- and from- dialyzer tubes are linear peristaltic pump tubing segments.

8. The hemodialysis system of claim 1, wherein the second machine portion includes a heater and the dialysate cassette includes an inline fluid heating pathway positioned and arranged to operate with the heater.

9. The hemodialysis system of claim 1, wherein the dialysate cassette is loaded horizontally with respect to the second machine portion.

10. The hemodialysis system of claim 1, wherein the first and second machine portions are separated by a user interface.

11. The hemodialysis system of claim 1, wherein the dialysate cassette includes a plurality of inlet tubes positioned and arranged to be selectively pinched closed at the second machine portion.

12. The hemodialysis system of claim 1, the dialysate pump a peristaltic pump, and which includes a moveable member for loading the dialysate cassette and against which a broad side of the dialysate cassette is abutted, the moveable member including an indentation for accepting a tube of the dialysate cassette when actuated by the peristaltic dialysate pump.

13. The hemodialysis system of claim 12, wherein the member is a door moveably connected to the second machine portion.

14. A hemodialysis system for operation with a blood source and a dialysate source, the system comprising:

a first machine portion including a blood pump;

a blood cassette operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette when the blood cassette is in fluid communication with the blood source;

a dialyzer fluidly connected to the blood cassette;

a second machine portion separate from the first machine portion, the second machine portion including a dialysate pump; and

a dialysate cassette separate from the blood cassette, the dialysate cassette operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette when the dialysate cassette is in fluid communication with the dialysate source, the dialysate cassette being fluidly connected to the dialyzer,

wherein the blood pump is a peristaltic blood pump and the dialysate pump is a peristaltic dialysate pump, the blood cassette including a pumping tube for operation with the peristaltic blood pump and the dialysate cassette including a pumping tube for operation with the peristaltic dialysate pump.

15. A hemodialysis system for operation with a blood source and a dialysate source, the system comprising:

a machine housing;

a peristaltic blood pump supported by the housing;

a peristaltic to-dialyzer pump supported by the housing;

a peristaltic from-dialyzer pump supported by the housing;

a blood cassette including a blood pumping tube, the blood cassette removeably accepted by the housing such that the blood pumping tube can be operated by the blood pump; and

a dialysate cassette, the dialysate cassette including a to-dialyzer tube and a from-dialyzer tube, the dialysate cassette removeably accepted by the housing, separate from the blood cassette, such that the to-dialyzer tube and the from-dialyzer tube can be operated by the to-dialyzer pump and the from-dialyzer pump, respectively.

16. The hemodialysis system of claim 15, wherein the housing is configured to gravimetrically weigh the dialysate cassette for dialysate flow control.

17. The hemodialysis system of claim 15, wherein the blood cassette and the dialysate cassette are each connected to a dialyzer.

18. A method for enabling a treatment to be setup on a hemodialysis machine, the method comprising:

providing a blood cassette including a blood pumping tube;

linearly disposing first and second dialysate pumping tubes on a dialysate cassette;

structuring the dialysis machine so that the blood cassette can be installed on the machine with the blood pumping tube engaging a blood pump of the machine adjacent to the blood cassette;

further structuring the dialysis machine so that the dialysate cassette can be installed independent of the blood cassette, and so that the first and second linearly disposed dialysate pumping tubes can be simultaneously mated for operation, on a first side of the dialysate cassette, with first and second peristaltic dialysate pumps of the machine, the mating occurring in the direction that the dialysate cassette is installed; and

enabling a second side of the dialysate cassette to be clamped such that first and second pump races are positioned on opposing sides of the first and second dialysate pumping tubes from the first and second peristaltic dialysate pumps, respectively.

19. The method of claim 18, wherein the clamping also clamps the cassette together for pressurized fluid flow within.