Low profile improved radiopacity intraluminal medical device

• US 8,882,829 B2
• Filed: 06/12/2012
• Issued: 11/11/2014
• Est. Priority Date: 06/19/2001
• Status: Expired due to Term

• Current Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Gladdish, Bennie W. Jr., Nino, Marco, Shaw, William D. Jr., Sijbolts, Durk C., Vaughan, Dennis B.
• Primary Examiner(s): SEVERSON, RYAN J
• Application Number:
  US13/494,416
• Publication Number:
  US 20120253455A1
• Time in Patent Office: 882 Days
• Field of Search: 623/1.15, 623/1.34
• US Class Current: 623/1.34
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61F 2310/0097 Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
• CPC Class Codes: A61L 2400/16 Materials with shape-memory or superelastic properties
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: C08L 27/12 containing fluorine atoms

Abstract

A stent or other intraluminal medical device having markers formed from housings integral with the stent and marker inserts having a higher radiopacity than the stent provides for more precise placement and post-procedural visualization in a vessel, by increasing the radiopacity of the stent under X-ray fluoroscopy. The housings are formed integral to the stent and the marker inserts are made from a material close in the galvanic series to the stent material and sized to substantially minimize the effect of galvanic corrosion. The housings are also shaped to minimize their impact on the overall profile of the stent.

Claims

1. An intraluminal medical device comprising:

a substantially tubular member having open ends, and a first diameter for insertion into a lumen of a vessel and a second diameter for anchoring in the lumen of the vessel; and

at least one marker connected to at least one end of the substantially tubular member, the at least one marker comprising a marker housing having a substantially oval shape with a continuous perimeter and a marker insert having a substantially oval shape, both having a radius of curvature equal to the radius of curvature of the substantially tubular member.

2. The intraluminal medical device according to claim 1, wherein the intraluminal medical device comprises a supereleastic alloy.

3. The intraluminal medical device according to claim 2, wherein the marker housing comprises the same material as the intraluminal medical device and is integral thereto, thereby forming a unitary structure.

4. The intraluminal medical device according to claim 3, wherein the marker insert comprises a material having a radiopacity higher than that of the material comprising the intraluminal medical device.

5. The intraluminal medical device according to claim 4, wherein the marker insert comprises Tantalum.

6. The intraluminal medical device according to claim 5, wherein the marker insert is secured in the marker housing by frictional, locking engagement.

7. The intraluminal medical device according to claim 6, wherein the marker insert is secured in the marker housing by a protruding ridge.

8. An intraluminal medical device comprising:

a thin-walled, substantially tubular member, defining a longitudinal axis with a radius of curvature, having open ends, and a first diameter for insertion into a lumen of a vessel and a second diameter for anchoring in the lumen of the vessel, the thin-walled tubular member comprising a superelastic alloy, the substantially tubular member comprising a plurality of adjacent hoops interconnected by a plurality of bridges, the plurality of adjacent hoops being formed from a plurality of longitudinal struts and a plurality of loops connecting adjacent struts; and

at least one marker extending from and connected to at least one end of the thin-walled, substantially tubular member, the at least one marker comprising a marker housing having a substantially circular shape with a continuous perimeter defining a circumference having first and second flattened sections, wherein the first and second flattened sections are aligned with the longitudinal axis, substantially parallel to the plurality of longitudinal struts when the substantially tubular member is at its first diameter and to each other and a marker insert, both having a radius of curvature equal to the radius of curvature of the substantially tubular member.

9. The intraluminal medical device according to claim 8, wherein the marker housing comprises the same material as the intraluminal medical device and is integral thereto, thereby forming a unitary structure.

10. The intraluminal medical device according to claim 9, wherein the marker housing defines a substantially elliptical opening having a predetermined curvature.

11. The intraluminal medical device according to claim 10, wherein the marker insert comprises a material having a radiopacity higher than that of the material comprising the intraluminal medical device.

12. The intraluminal medical device according to claim 11, therein the marker insert comprises Tantalum.

13. The intraluminal medical device according to claim 12, wherein the marker insert has a curvature equal to that of the curvature of the opening in the marker housing.

14. The intraluminal medical device according to claim 13, wherein the marker insert has a diameter of 0.02 inches.

15. The intraluminal medical device according to claim 14, wherein the marker insert is secured in the marker housing by frictional, locking engagement.

16. The intraluminal medical device according to claim 15, wherein the marker insert is secured in the marker housing by a protruding ridge.

17. A stent comprising:

a thin-walled, substantially tubular member defining a longitudinal axis with a radius of curvature, having open ends, and a first diameter for insertion into a lumen of a vessel and a second diameter for anchoring in the lumen of the vessel, the thin-walled tubular member comprising a superelastic alloy, the substantially tubular member comprising a plurality of adjacent hoops interconnected by a plurality of bridges, the plurality of adjacent hoops being formed from a plurality of longitudinal struts and a plurality of loops connecting adjacent struts; and

at least one marker extending from and connected to at least one end of the thin-walled, substantially tubular member, the at least one marker comprising a marker housing having a substantially circular shape with a continuous perimeter, defining a circumference having first and second flattened sections, wherein the first and second flattened sections are aligned with the longitudinal axis, and a marker insert, both having a radius of curvature equal to the radius of curvature of the substantially tubular member.

18. The stent according to claim 17, wherein the marker housing comprises the same material as the stent and is integral thereto, thereby forming a unitary structure.

19. The stent according to claim 18, wherein the marker housing defines a substantially elliptical opening having a predetermined curvature.

20. The stent according to claim 19, wherein the marker insert comprises a material having a radiopacity higher than that of the material comprising the stent.

21. The stent according to claim 20, wherein the marker insert comprises Tantalum.

22. The stent according to claim 21, wherein the marker insert has a curvature equal to that of the curvature of the opening in the marker housing.

23. The stent according to claim 22, wherein the marker insert has a diameter of 0.02 inches.

24. The stent according to claim 23, wherein the marker insert is secured in the marker housing by frictional, locking engagement.

25. The intraluminal medical device according to claim 24, wherein the marker insert is secured in the marker housing by a protruding ridge.

26. The stent according to claim 17, further comprising six markers attached to each end of the thin-walled, substantially tubular member.